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Protein
Submitted name:

Polycomb protein EED

Gene

EED

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

SignaLinkiE9PJK2.

Names & Taxonomyi

Protein namesi
Submitted name:
Polycomb protein EEDImported
Gene namesi
Name:EEDImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:3188. EED.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000074266.

PTM / Processingi

Proteomic databases

EPDiE9PJK2.
MaxQBiE9PJK2.
PeptideAtlasiE9PJK2.
PRIDEiE9PJK2.

Expressioni

Gene expression databases

BgeeiENSG00000074266.
ExpressionAtlasiE9PJK2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PJK2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini186 – 228WD_REPEATS_REGIONInterPro annotationAdd BLAST43

Phylogenomic databases

GeneTreeiENSGT00510000047334.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 4 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PJK2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEREVSTAP AGTDMPAAKK QKLSSDENSN PDLSGDENDD AVSIESGTNT
60 70 80 90 100
ERPDTPTNTP NAPGRKSWGK GKWKSKKCKY SFKCVNSLKE DHNQPLFGVQ
110 120 130 140 150
FNWHSKEGDP LVFATVGSNR VTLYECHSQG EIRLLQSYVD ADADENFYTC
160 170 180 190 200
AWTYDSNTSH PLLAVAGSRG IIRIINPITM QCIKHYVGHG NAINELKFHP
210 220 230 240 250
RDPNLLLSVS KDHALRLWNI QTDTLVAIFG GVEGHRDEVL SASCENAIVC
260 270 280 290 300
WKPGKMEDDI DKIKPSESNV TILGRFDYSQ CDIWYMRFSM DFWQKMLALG
310 320 330 340 350
NQVGKLYVWD LEVEDPHKAK CTTLTHHKCG AAIRQTSFSR DSSILIAVCD
360
DASIWRWDRL R
Length:361
Mass (Da):40,635
Last modified:April 5, 2011 - v1
Checksum:iB8E21C011F16AA49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003084 Genomic DNA. No translation available.
RefSeqiNP_001317263.1. NM_001330334.1.
UniGeneiHs.503510.
Hs.528103.

Genome annotation databases

EnsembliENST00000528180; ENSP00000431778; ENSG00000074266.
GeneIDi8726.
UCSCiuc058gfr.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003084 Genomic DNA. No translation available.
RefSeqiNP_001317263.1. NM_001330334.1.
UniGeneiHs.503510.
Hs.528103.

3D structure databases

ProteinModelPortaliE9PJK2.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiE9PJK2.
MaxQBiE9PJK2.
PeptideAtlasiE9PJK2.
PRIDEiE9PJK2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000528180; ENSP00000431778; ENSG00000074266.
GeneIDi8726.
UCSCiuc058gfr.1. human.

Organism-specific databases

CTDi8726.
HGNCiHGNC:3188. EED.
OpenTargetsiENSG00000074266.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00510000047334.

Enzyme and pathway databases

SignaLinkiE9PJK2.

Miscellaneous databases

ChiTaRSiEED. human.
GenomeRNAii8726.

Gene expression databases

BgeeiENSG00000074266.
ExpressionAtlasiE9PJK2. baseline and differential.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 4 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9PJK2_HUMAN
AccessioniPrimary (citable) accession number: E9PJK2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 30, 2016
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.