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Protein

Tyrosine-protein phosphatase

Gene

PTPRJ

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphataseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine-protein phosphataseUniRule annotation (EC:3.1.3.48UniRule annotation)
Gene namesi
Name:PTPRJImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000149177.12
HGNCiHGNC:9673 PTPRJ

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000149177

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 35Sequence analysisAdd BLAST35
ChainiPRO_500841394536 – 146Tyrosine-protein phosphataseSequence analysisAdd BLAST111

Proteomic databases

PeptideAtlasiE9PJ83

Expressioni

Gene expression databases

BgeeiENSG00000149177
ExpressionAtlasiE9PJ83 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PJ83
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0791 Eukaryota
COG5599 LUCA
GeneTreeiENSGT00900000140785

Sequencei

Sequence statusi: Fragment.

E9PJ83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPAAREARL PPRSPGLRWA LPLLLLLLRL GQILCAGGTP SPIPDPSVAT
60 70 80 90 100
VATGENGITQ ISSTAESFHK QNGTGTPQVE TNTSEDGESS GANDSLRTPE
110 120 130 140
QGSNGTDGAS QKTPSSTEPI PVSDLRVALT GVRKAALSWS NGNGTA
Length:146
Mass (Da):14,970
Last modified:October 5, 2016 - v8
Checksum:iDE636FFE8FD85022
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei146Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC026975 Genomic DNA No translation available.
AC103828 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000527952; ENSP00000435618; ENSG00000149177
UCSCiuc058bir.1 human

Similar proteinsi

Entry informationi

Entry nameiE9PJ83_HUMAN
AccessioniPrimary (citable) accession number: E9PJ83
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 5, 2016
Last modified: May 23, 2018
This is version 51 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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