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Protein
Submitted name:

Baculoviral IAP repeat-containing protein 2

Gene

BIRC2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Baculoviral IAP repeat-containing protein 2Imported
Gene namesi
Name:BIRC2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:590. BIRC2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000110330.

PTM / Processingi

Proteomic databases

PaxDbiE9PIW1.
PeptideAtlasiE9PIW1.
PRIDEiE9PIW1.

Expressioni

Gene expression databases

BgeeiENSG00000110330.
ExpressionAtlasiE9PIW1. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini115 – 182CARDInterPro annotationAdd BLAST68

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili89 – 118Sequence analysisAdd BLAST30

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1101. Eukaryota.
ENOG410YPNM. LUCA.
GeneTreeiENSGT00500000044782.

Family and domain databases

InterProiView protein in InterPro
IPR028795. C-IAP1.
IPR001315. CARD.
IPR011029. DEATH-like_dom.
PANTHERiPTHR10044:SF150. PTHR10044:SF150. 1 hit.
PfamiView protein in Pfam
PF00619. CARD. 1 hit.
SMARTiView protein in SMART
SM00114. CARD. 1 hit.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiView protein in PROSITE
PS50209. CARD. 1 hit.

Sequencei

Sequence statusi: Fragment.

E9PIW1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGQEFVDEI QGRYPHLLEQ LLSTSDTTGE ENADPPIIHF GPGESSSEDA
60 70 80 90 100
VMMNTPVVKS ALEMGFNRDL VKQTVQSKIL TTGENYKTVN DIVSALLNAE
110 120 130 140 150
DEKREEEKEK QAEEMASDDL SLIRKNRMAL FQQLTCVLPI LDNLLKANVI
160 170 180
NKQEHDIIKQ KTQIPLQARE LIDTILVKGN AA
Length:182
Mass (Da):20,390
Last modified:October 5, 2016 - v8
Checksum:iE837AC58A27A01F8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei182Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000942 Genomic DNA. No translation available.
KF455475 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000533742; ENSP00000433851; ENSG00000110330.
UCSCiuc058gvd.1. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiE9PIW1_HUMAN
AccessioniPrimary (citable) accession number: E9PIW1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 5, 2016
Last modified: July 5, 2017
This is version 53 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported