##gff-version 3
O14521	UniProtKB	Transit peptide	1	56	.	.	.	Note=Mitochondrion;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O14521	UniProtKB	Chain	57	159	.	.	.	ID=PRO_0000006487;Note=Succinate dehydrogenase [ubiquinone] cytochrome b small subunit%2C mitochondrial	
O14521	UniProtKB	Topological domain	57	63	.	.	.	Note=Mitochondrial matrix;Ontology_term=ECO:0000250;evidence=ECO:0000250	
O14521	UniProtKB	Transmembrane	64	85	.	.	.	Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250	
O14521	UniProtKB	Topological domain	86	90	.	.	.	Note=Mitochondrial intermembrane;Ontology_term=ECO:0000250;evidence=ECO:0000250	
O14521	UniProtKB	Transmembrane	91	111	.	.	.	Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250	
O14521	UniProtKB	Topological domain	112	120	.	.	.	Note=Mitochondrial matrix;Ontology_term=ECO:0000250;evidence=ECO:0000250	
O14521	UniProtKB	Transmembrane	121	142	.	.	.	Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250	
O14521	UniProtKB	Topological domain	143	159	.	.	.	Note=Mitochondrial intermembrane;Ontology_term=ECO:0000250;evidence=ECO:0000250	
O14521	UniProtKB	Binding site	102	102	.	.	.	Note=Axial binding residue;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:A5GZW8	
O14521	UniProtKB	Binding site	114	114	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
O14521	UniProtKB	Alternative sequence	19	57	.	.	.	ID=VSP_054744;Note=In isoform 2. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O14521	UniProtKB	Alternative sequence	56	158	.	.	.	ID=VSP_054745;Note=In isoform 3. HSGSKAASLHWTSERVVSVLLLGLLPAAYLNPCSAMDYSLAAALTLHGHWGLGQVVTDYVHGDALQKAAKAGLLALSALTFAGLCYFNYHDVGICKAVAMLWK->HWALDKLLLTMFMGMPCRKLPRQGFWHFQ;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O14521	UniProtKB	Alternative sequence	106	143	.	.	.	ID=VSP_054746;Note=In isoform 4. GLGQVVTDYVHGDALQKAAKAGLLALSALTFAGLCYFN->LECNGAILARHDLGSARSQLTATSAFRVQAILLPQPPK;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O14521	UniProtKB	Alternative sequence	144	159	.	.	.	ID=VSP_054747;Note=In isoform 4. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O14521	UniProtKB	Natural variant	12	12	.	.	.	ID=VAR_017870;Note=Probable risk factor for pheochromocytoma%2C paraganglioma%2C intestinal carcinoid tumor and breast%2C renal and uterus carcinoma%3B increased manganese superoxide dismutase expression and increased reactive oxygen species%3B results in 1.9-fold increase in both AKT and MAPK expression. G->S;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:11526495,ECO:0000269|PubMed:12007193,ECO:0000269|PubMed:12696072,ECO:0000269|PubMed:14500403,ECO:0000269|PubMed:15032977,ECO:0000269|PubMed:18678321,ECO:0000269|PubMed:18987736;Dbxref=dbSNP:rs34677591,PMID:11526495,PMID:12007193,PMID:12696072,PMID:14500403,PMID:15032977,PMID:18678321,PMID:18987736	
O14521	UniProtKB	Natural variant	50	50	.	.	.	ID=VAR_017871;Note=Probable risk factor for paraganglioma%2C breast and thyroid carcinoma%3B may be involved in somatic Merkel cell carcinoma%3B increased manganese superoxide dismutase expression and increased reactive oxygen species%3B results in a 2.0-fold increase in AKT expression and a 1.7-fold increase in MAPK expression. H->R;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12007193,ECO:0000269|PubMed:12696072,ECO:0000269|PubMed:14500403,ECO:0000269|PubMed:18678321;Dbxref=dbSNP:rs11214077,PMID:12007193,PMID:12696072,PMID:14500403,PMID:18678321	
O14521	UniProtKB	Natural variant	69	69	.	.	.	ID=VAR_074105;Note=In MC2DN3%3B results in impaired mitochondrial complex II assembly%3B results in impaired cellular respiration. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:24367056;Dbxref=dbSNP:rs202198133,PMID:24367056	
O14521	UniProtKB	Natural variant	81	81	.	.	.	ID=VAR_010038;Note=In PPGL1. P->L;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10657297,ECO:0000269|PubMed:11156372,ECO:0000269|PubMed:15328326;Dbxref=dbSNP:rs80338844,PMID:10657297,PMID:11156372,PMID:15328326	
O14521	UniProtKB	Natural variant	92	92	.	.	.	ID=VAR_074106;Note=In MC2DN3%3B results in highly reduced protein expression%3B results in impaired cellular respiration. D->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26008905;Dbxref=dbSNP:rs786205436,PMID:26008905	
O14521	UniProtKB	Natural variant	92	92	.	.	.	ID=VAR_010039;Note=In PPGL1. D->Y;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10657297,ECO:0000269|PubMed:11391798,ECO:0000269|PubMed:12000816,ECO:0000269|PubMed:15328326;Dbxref=dbSNP:rs80338845,PMID:10657297,PMID:11391798,PMID:12000816,PMID:15328326	
O14521	UniProtKB	Natural variant	93	93	.	.	.	ID=VAR_018519;Note=In PPGL1. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11391796;Dbxref=dbSNP:rs121908983,PMID:11391796	
O14521	UniProtKB	Natural variant	102	102	.	.	.	ID=VAR_010040;Note=In PPGL1. H->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10657297;Dbxref=dbSNP:rs104894302,PMID:10657297	
O14521	UniProtKB	Natural variant	114	114	.	.	.	ID=VAR_017872;Note=In PPGL1. Y->C;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:11343322,ECO:0000269|PubMed:15328326;Dbxref=dbSNP:rs104894304,PMID:11343322,PMID:15328326	
O14521	UniProtKB	Natural variant	139	139	.	.	.	ID=VAR_017873;Note=In PPGL1. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11391798;Dbxref=dbSNP:rs80338847,PMID:11391798	
O14521	UniProtKB	Natural variant	145	145	.	.	.	ID=VAR_054384;Note=Found in an individual with features of Cowden syndrome%3B uncertain significance%3B increased manganese superoxide dismutase expression and normal reactive oxygen species%3B no change in AKT expression but a 1.2-fold increase of MAPK expression. H->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18678321;Dbxref=dbSNP:rs121908984,PMID:18678321	
O14521	UniProtKB	Natural variant	148	148	.	.	.	ID=VAR_054385;Note=In PPGL1. G->V;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15328326;Dbxref=dbSNP:rs1555187633,PMID:15328326	
O14521	UniProtKB	Sequence conflict	74	74	.	.	.	Note=V->F;Ontology_term=ECO:0000305;evidence=ECO:0000305