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Protein
Submitted name:

Mitochondrial carrier homolog 2

Gene

MTCH2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Mitochondrial carrier homolog 2Imported
Gene namesi
Name:MTCH2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:17587. MTCH2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiE9PIE4.
PaxDbiE9PIE4.

Expressioni

Gene expression databases

BgeeiE9PIE4.
ExpressionAtlasiE9PIE4. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000303222.

Structurei

3D structure databases

ProteinModelPortaliE9PIE4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG2745. Eukaryota.
ENOG410XSXF. LUCA.
GeneTreeiENSGT00390000000020.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 1 hit.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9PIE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADAASQVLL GSGLTILSQP LMYVKVLIQV GYEPLPPTIG RNIFGRQVCQ
60 70 80 90 100
LPGLFSYAQH IASIDGRRGL FTGLTPRLCS GVLGTVVHGK VLQELGPGNV
110 120 130 140 150
QKEVSSSFDH VIKETTREMI ARSAATLITH PFHVITLRSM VQFIGRESKY
160 170 180 190 200
CGLCDSIITI YREEGILGFF AGLVPRLLGD ILSLWLCNSL AYLVNTYALD
210 220 230 240 250
SGVSTMNEMK SYSQAVTGFF ASMLTYPFVL VSNLMAVNNC GLAGGCPPYS
260
PIYTSWIDCW CML
Length:263
Mass (Da):28,663
Last modified:February 17, 2016 - v7
Checksum:iCC7E2B3DDA4E62D2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei263 – 2631Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104942 Genomic DNA. No translation available.
KF455384 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000530428; ENSP00000432043; ENSG00000109919.
UCSCiuc058bgz.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104942 Genomic DNA. No translation available.
KF455384 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9PIE4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000303222.

Proteomic databases

EPDiE9PIE4.
PaxDbiE9PIE4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000530428; ENSP00000432043; ENSG00000109919.
UCSCiuc058bgz.1. human.

Organism-specific databases

HGNCiHGNC:17587. MTCH2.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2745. Eukaryota.
ENOG410XSXF. LUCA.
GeneTreeiENSGT00390000000020.

Miscellaneous databases

ChiTaRSiMTCH2. human.
NextBioi35502246.

Gene expression databases

BgeeiE9PIE4.
ExpressionAtlasiE9PIE4. baseline and differential.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 1 hit.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
  5. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. "N-terminome analysis of the human mitochondrial proteome."
    Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.
    Proteomics 15:2519-2524(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiE9PIE4_HUMAN
AccessioniPrimary (citable) accession number: E9PIE4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: February 17, 2016
Last modified: May 11, 2016
This is version 39 of the entry and version 7 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.