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Protein
Submitted name:

HLA class II histocompatibility antigen, DQ beta 1 chain

Gene

HLA-DQB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
HLA class II histocompatibility antigen, DQ beta 1 chainImported
Gene namesi
Name:HLA-DQB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000179344.16.
HGNCiHGNC:4944. HLA-DQB1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000179344.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_500324285131 – 136Sequence analysisAdd BLAST106

Proteomic databases

EPDiE9PIB1.
PeptideAtlasiE9PIB1.
PRIDEiE9PIB1.

Expressioni

Gene expression databases

BgeeiENSG00000179344.
ExpressionAtlasiE9PIB1. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PIB1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 119MHC_II_betaInterPro annotationAdd BLAST75

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IWG3. Eukaryota.
ENOG410YI0S. LUCA.
GeneTreeiENSGT00900000140849.

Family and domain databases

Gene3Di3.10.320.10. 1 hit.
InterProiView protein in InterPro
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
PfamiView protein in Pfam
PF00969. MHC_II_beta. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD000328. MHC_II_b_N. 1 hit.
SMARTiView protein in SMART
SM00921. MHC_II_beta. 1 hit.
SUPFAMiSSF54452. SSF54452. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PIB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWKKALRIP GDLRVATVTL MLAMLSSLLA EGRDSPEDFV FQFKGMCYFT
60 70 80 90 100
NGTERVRLVT RYIYNREEYA RFDSDVGVYR AVTPQGRPDA EYWNSQKEVL
110 120 130
EGTRAELDTV CRHNYEVAFR GILQRRGMVT GLSRSW
Length:136
Mass (Da):15,771
Last modified:April 5, 2011 - v1
Checksum:i1E895654821FEA00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662789 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000484729; ENSP00000436686; ENSG00000179344.
UCSCiuc063nrl.1. human.

Similar proteinsi

Entry informationi

Entry nameiE9PIB1_HUMAN
AccessioniPrimary (citable) accession number: E9PIB1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported