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Protein
Submitted name:

Interferon regulatory factor 7

Gene

IRF7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor 7Imported
Gene namesi
Name:IRF7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000185507.19.
HGNCiHGNC:6122. IRF7.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185507.

Expressioni

Gene expression databases

BgeeiENSG00000185507.
ExpressionAtlasiE9PIA7. baseline and differential.

Structurei

3D structure databases

SMRiE9PIA7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 126IRF tryptophan pentad repeatInterPro annotationAdd BLAST116

Sequence similaritiesi

Belongs to the IRF family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IWNR. Eukaryota.
ENOG4111G85. LUCA.
GeneTreeiENSGT00760000119093.

Family and domain databases

CDDicd00103. IRF. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR019817. Interferon_reg_fac_CS.
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
PANTHERiPTHR11949. PTHR11949. 1 hit.
PfamiView protein in Pfam
PF00605. IRF. 1 hit.
PRINTSiPR00267. INTFRNREGFCT.
SMARTiView protein in SMART
SM00348. IRF. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS00601. IRF_1. 1 hit.
PS51507. IRF_2. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PIA7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALAPERAAP RVLFGEWLLG EISSGCYEGL QWLDEARTCF RVPWKHFARK
60 70 80 90 100
DLSEADARIF KAWAVARGRW PPSSRGGGPP PEAETAERAG WKTNFRCALR
110 120 130 140 150
STRRFVMLRD NSGDPADPHK VYALSRELCW RGPGTDQTEA EAPAAVPPPQ
160 170 180
ARPRPQSPRT RQSRTCHPPQ APAPRCKSPA QGRWT
Length:185
Mass (Da):20,693
Last modified:April 5, 2011 - v1
Checksum:i4E85B94909D9109E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138374 Genomic DNA. No translation available.
AP006284 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000532326; ENSP00000436696; ENSG00000185507.
ENST00000632194; ENSP00000487875; ENSG00000276561.
UCSCiuc057xit.1. human.

Similar proteinsi

Entry informationi

Entry nameiE9PIA7_HUMAN
AccessioniPrimary (citable) accession number: E9PIA7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 27, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported