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Protein
Submitted name:

Interferon regulatory factor 7

Gene

IRF7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor 7Imported
Gene namesi
Name:IRF7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000185507.19
HGNCiHGNC:6122 IRF7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185507

PTM / Processingi

Proteomic databases

PeptideAtlasiE9PIA7
PRIDEiE9PIA7

Expressioni

Gene expression databases

BgeeiENSG00000185507
ExpressionAtlasiE9PIA7 baseline and differential

Structurei

3D structure databases

SMRiE9PIA7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 126IRF tryptophan pentad repeatInterPro annotationAdd BLAST116

Sequence similaritiesi

Belongs to the IRF family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IWNR Eukaryota
ENOG4111G85 LUCA
GeneTreeiENSGT00760000119093

Family and domain databases

CDDicd00103 IRF, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR019817 Interferon_reg_fac_CS
IPR001346 Interferon_reg_fact_DNA-bd_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR11949 PTHR11949, 1 hit
PfamiView protein in Pfam
PF00605 IRF, 1 hit
PRINTSiPR00267 INTFRNREGFCT
SMARTiView protein in SMART
SM00348 IRF, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00601 IRF_1, 1 hit
PS51507 IRF_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9PIA7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALAPERAAP RVLFGEWLLG EISSGCYEGL QWLDEARTCF RVPWKHFARK
60 70 80 90 100
DLSEADARIF KAWAVARGRW PPSSRGGGPP PEAETAERAG WKTNFRCALR
110 120 130 140 150
STRRFVMLRD NSGDPADPHK VYALSRELCW RGPGTDQTEA EAPAAVPPPQ
160 170 180
ARPRPQSPRT RQSRTCHPPQ APAPRCKSPA QGRWT
Length:185
Mass (Da):20,693
Last modified:April 5, 2011 - v1
Checksum:i4E85B94909D9109E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138374 Genomic DNA No translation available.
AP006284 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000532326; ENSP00000436696; ENSG00000185507
ENST00000632194; ENSP00000487875; ENSG00000276561
UCSCiuc057xit.1 human

Similar proteinsi

Entry informationi

Entry nameiE9PIA7_HUMAN
AccessioniPrimary (citable) accession number: E9PIA7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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