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Protein
Submitted name:

Phosphatidylinositol-binding clathrin assembly protein

Gene

PICALM

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylinositol-binding clathrin assembly proteinImported
Gene namesi
Name:PICALMImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:15514. PICALM.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiE9PI56.
PaxDbiE9PI56.
PeptideAtlasiE9PI56.

Expressioni

Gene expression databases

BgeeiE9PI56.
ExpressionAtlasiE9PI56. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000377015.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 9494ENTH (epsin N-terminal homology)InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0251. Eukaryota.
ENOG410XQ90. LUCA.
GeneTreeiENSGT00390000008805.

Family and domain databases

Gene3Di1.20.58.150. 1 hit.
1.25.40.90. 1 hit.
InterProiIPR011417. ANTH_dom.
IPR014712. Clathrin_AP_2.
IPR013809. ENTH.
IPR008942. ENTH_VHS.
IPR030412. PICALM.
[Graphical view]
PANTHERiPTHR22951:SF16. PTHR22951:SF16. 1 hit.
PfamiPF07651. ANTH. 1 hit.
[Graphical view]
SMARTiSM00273. ENTH. 1 hit.
[Graphical view]
SUPFAMiSSF48464. SSF48464. 1 hit.
PROSITEiPS50942. ENTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9PI56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVNIPQLAD SLFERTTNSS WVVVFKSLIT THHLMVYGNE RFIQYLASRN
60 70 80 90 100
TLFNLSNFLD KSGLQGYDMS TFIRRYSRYL NEKAVSYRQV AFDFTKVKRG
110 120 130 140
ADGVMRTMNT EKLLKTVPII QNQMDALLDF NVNSNELTNG VINAAFML
Length:148
Mass (Da):17,050
Last modified:February 17, 2016 - v7
Checksum:iEDA6C7A574724072
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei148 – 1481Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000767 Genomic DNA. No translation available.
KF455430 Genomic DNA. No translation available.
KF511164 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000525162; ENSP00000436508; ENSG00000073921.
UCSCiuc058gfl.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000767 Genomic DNA. No translation available.
KF455430 Genomic DNA. No translation available.
KF511164 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000377015.

Proteomic databases

EPDiE9PI56.
PaxDbiE9PI56.
PeptideAtlasiE9PI56.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000525162; ENSP00000436508; ENSG00000073921.
UCSCiuc058gfl.1. human.

Organism-specific databases

HGNCiHGNC:15514. PICALM.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0251. Eukaryota.
ENOG410XQ90. LUCA.
GeneTreeiENSGT00390000008805.

Miscellaneous databases

ChiTaRSiPICALM. human.

Gene expression databases

BgeeiE9PI56.
ExpressionAtlasiE9PI56. baseline and differential.

Family and domain databases

Gene3Di1.20.58.150. 1 hit.
1.25.40.90. 1 hit.
InterProiIPR011417. ANTH_dom.
IPR014712. Clathrin_AP_2.
IPR013809. ENTH.
IPR008942. ENTH_VHS.
IPR030412. PICALM.
[Graphical view]
PANTHERiPTHR22951:SF16. PTHR22951:SF16. 1 hit.
PfamiPF07651. ANTH. 1 hit.
[Graphical view]
SMARTiSM00273. ENTH. 1 hit.
[Graphical view]
SUPFAMiSSF48464. SSF48464. 1 hit.
PROSITEiPS50942. ENTH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PI56_HUMAN
AccessioniPrimary (citable) accession number: E9PI56
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: February 17, 2016
Last modified: July 6, 2016
This is version 39 of the entry and version 7 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.