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Protein
Submitted name:

Dystonin

Gene

DST

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Actin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
DystoninImported
Gene namesi
Name:DSTImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:1090. DST.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiE9PHM6.
PaxDbiE9PHM6.
PeptideAtlasiE9PHM6.
PRIDEiE9PHM6.

Expressioni

Gene expression databases

BgeeiE9PHM6.
ExpressionAtlasiE9PHM6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000244364.

Structurei

3D structure databases

ProteinModelPortaliE9PHM6.
SMRiE9PHM6. Positions 31-255, 583-795.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini35 – 138104Actin-bindingInterPro annotationAdd
BLAST
Domaini151 – 252102Actin-bindingInterPro annotationAdd
BLAST
Domaini5111 – 514636EF-handInterPro annotationAdd
BLAST
Domaini5147 – 518236EF-handInterPro annotationAdd
BLAST
Domaini5187 – 526579GARInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili12 – 3928Sequence analysisAdd
BLAST
Coiled coili734 – 76835Sequence analysisAdd
BLAST
Coiled coili840 – 86324Sequence analysisAdd
BLAST
Coiled coili1208 – 124235Sequence analysisAdd
BLAST
Coiled coili1418 – 144831Sequence analysisAdd
BLAST
Coiled coili1504 – 153128Sequence analysisAdd
BLAST
Coiled coili1637 – 167135Sequence analysisAdd
BLAST
Coiled coili1853 – 188028Sequence analysisAdd
BLAST
Coiled coili2260 – 228728Sequence analysisAdd
BLAST
Coiled coili2415 – 243925Sequence analysisAdd
BLAST
Coiled coili2472 – 249928Sequence analysisAdd
BLAST
Coiled coili2686 – 272035Sequence analysisAdd
BLAST
Coiled coili2971 – 299828Sequence analysisAdd
BLAST
Coiled coili3018 – 304528Sequence analysisAdd
BLAST
Coiled coili3118 – 314831Sequence analysisAdd
BLAST
Coiled coili3162 – 320039Sequence analysisAdd
BLAST
Coiled coili4108 – 413528Sequence analysisAdd
BLAST
Coiled coili4214 – 425845Sequence analysisAdd
BLAST
Coiled coili4360 – 439839Sequence analysisAdd
BLAST
Coiled coili4869 – 489931Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IQBP. Eukaryota.
ENOG410XP41. LUCA.
GeneTreeiENSGT00760000119163.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
1.10.418.10. 2 hits.
3.30.920.20. 1 hit.
InterProiIPR001589. Actinin_actin-bd_CS.
IPR001715. CH-domain.
IPR029926. Dystonin.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR003108. GAS_dom.
IPR018159. Spectrin/alpha-actinin.
IPR002017. Spectrin_repeat.
[Graphical view]
PANTHERiPTHR11915:SF38. PTHR11915:SF38. 5 hits.
PfamiPF00307. CH. 2 hits.
PF13499. EF-hand_7. 1 hit.
PF02187. GAS2. 1 hit.
PF00435. Spectrin. 21 hits.
[Graphical view]
SMARTiSM00033. CH. 2 hits.
SM00054. EFh. 2 hits.
SM00243. GAS2. 1 hit.
SM00150. SPEC. 30 hits.
[Graphical view]
SUPFAMiSSF143575. SSF143575. 1 hit.
SSF47473. SSF47473. 1 hit.
SSF47576. SSF47576. 1 hit.
PROSITEiPS00019. ACTININ_1. 1 hit.
PS00020. ACTININ_2. 1 hit.
PS50021. CH. 2 hits.
PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS51460. GAR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PHM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGYLSPAAY LYVEEQEYLQ AYEDVLERYK DERDKVQKKT FTKWINQHLM
60 70 80 90 100
KVRKHVNDLY EDLRDGHNLI SLLEVLSGDT LPREKGRMRF HRLQNVQIAL
110 120 130 140 150
DYLKRRQVKL VNIRNDDITD GNPKLTLGLI WTIILHFQIS DIHVTGESED
160 170 180 190 200
MSAKERLLLW TQQATEGYAG IRCENFTTCW RDGKLFNAII HKYRPDLIDM
210 220 230 240 250
NTVAVQSNLA NLEHAFYVAE KIGVIRLLDP EDVDVSSPDE KSVITYVSSL
260 270 280 290 300
YDAFPKVPEG GEGIGANDVE VKWIEYQNMV NYLIQWIRHH VTTMSERTFP
310 320 330 340 350
NNPVELKALY NQYLQFKETE IPPKETEKSK IKRLYKLLEI WIEFGRIKLL
360 370 380 390 400
QGYHPNDIEK EWGKLIIAML EREKALRPEV ERLEMLQQIA NRVQRDSVIC
410 420 430 440 450
EDKLILAGNA LQSDSKRLES GVQFQNEAEI AGYILECENL LRQHVIDVQI
460 470 480 490 500
LIDGKYYQAD QLVQRVAKLR DEIMALRNEC SSVYSKGRIL TTEQTKLMIS
510 520 530 540 550
GITQSLNSGF AQTLHPSLTS GLTQSLTPSL TSSSMTSGLS SGMTSRLTPS
560 570 580 590 600
VTPAYTPGFP SGLVPNFSSG VEPNSLQTLK LMQIRKPLLK SSLLDQNLTE
610 620 630 640 650
EEINMKFVQD LLNWVDEMQV QLDRTEWGSD LPSVESHLEN HKNVHRAIEE
660 670 680 690 700
FESSLKEAKI SEIQMTAPLK LTYAEKLHRL ESQYAKLLNT SRNQERHLDT
710 720 730 740 750
LHNFVSRATN ELIWLNEKEE EEVAYDWSER NTNIARKKDY HAELMRELDQ
760 770 780 790 800
KEENIKSVQE IAEQLLLENH PARLTIEAYR AAMQTQWSWI LQLCQCVEQH
810 820 830 840 850
IKENTAYFEF FNDAKEATDY LRNLKDAIQR KYSCDRSSSI HKLEDLVQES
860 870 880 890 900
MEEKEELLQY KSTIANLMGK AKTIIQLKPR NSDCPLKTSI PIKAICDYRQ
910 920 930 940 950
IEITIYKDDE CVLANNSHRA KWKVISPTGN EAMVPSVCFT VPPPNKEAVD
960 970 980 990 1000
LANRIEQQYQ NVLTLWHESH INMKSVVSWH YLINEIDRIR ASNVASIKTM
1010 1020 1030 1040 1050
LPGEHQQVLS NLQSRFEDFL EDSQESQVFS GSDITQLEKE VNVCKQYYQE
1060 1070 1080 1090 1100
LLKSAEREEQ EESVYNLYIS EVRNIRLRLE NCEDRLIRQI RTPLERDDLH
1110 1120 1130 1140 1150
ESVFRITEQE KLKKELERLK DDLGTITNKC EEFFSQAAAS SSVPTLRSEL
1160 1170 1180 1190 1200
NVVLQNMNQV YSMSSTYIDK LKTVNLVLKN TQAAEALVKL YETKLCEEEA
1210 1220 1230 1240 1250
VIADKNNIEN LISTLKQWRS EVDEKRQVFH ALEDELQKAK AISDEMFKTY
1260 1270 1280 1290 1300
KERDLDFDWH KEKADQLVER WQNVHVQIDN RLRDLEGIGK SLKYYRDTYH
1310 1320 1330 1340 1350
PLDDWIQQVE TTQRKIQENQ PENSKTLATQ LNQQKMLVSE IEMKQSKMDE
1360 1370 1380 1390 1400
CQKYAEQYSA TVKDYELQTM TYRAMVDSQQ KSPVKRRRMQ SSADLIIQEF
1410 1420 1430 1440 1450
MDLRTRYTAL VTLMTQYIKF AGDSLKRLEE EEKSLEEEKK EHVEKAKELQ
1460 1470 1480 1490 1500
KWVSNISKTL KDAEKAGKPP FSKQKISSEE ISTKKEQLSE ALQTIQLFLA
1510 1520 1530 1540 1550
KHGDKMTDEE RNELEKQVKT LQESYNLLFS ESLKQLQESQ TSGDVKVEEK
1560 1570 1580 1590 1600
IVAERQQEYK EKLQGICDLL TQTENRLIGH QEAFMIGDGT VELKKYQSKQ
1610 1620 1630 1640 1650
EELQKDMQGS AQALAEVVKN TENFLKENGE KLSQEDKALI EQKLNEAKIK
1660 1670 1680 1690 1700
CEQLNLKAEQ SKKELDKVVT TAIKEETEKV AAVKQLEESK TKIENLLDWL
1710 1720 1730 1740 1750
SNVDKDSERA GTKHKQVIEQ NGTHFQEGDG KSAIGEEDEV NGNLLETDVD
1760 1770 1780 1790 1800
GQVGTTQENL NQQYQKVKAQ HEKIISQHQA VIIATQSAQV LLEKQGQYLS
1810 1820 1830 1840 1850
PEEKEKLQKN MKELKVHYET ALAESEKKMK LTHSLQEELE KFDADYTEFE
1860 1870 1880 1890 1900
HWLQQSEQEL ENLEAGADDI NGLMTKLKRQ KSFSEDVISH KGDLRYITIS
1910 1920 1930 1940 1950
GNRVLEAAKS CSKRDGGKVD TSATHREVQR KLDHATDRFR SLYSKCNVLG
1960 1970 1980 1990 2000
NNLKDLVDKY QHYEDASCGL LAGLQACEAT ASKHLSEPIA VDPKNLQRQL
2010 2020 2030 2040 2050
EETKALQGQI SSQQVAVEKL KKTAEVLLDA RGSLLPAKND IQKTLDDIVG
2060 2070 2080 2090 2100
RYEDLSKSVN ERNEKLQITL TRSLSVQDGL DEMLDWMGNV ESSLKEQGQV
2110 2120 2130 2140 2150
PLNSTALQDI ISKNIMLEQD IAGRQSSINA MNEKVKKFME TTDPSTASSL
2160 2170 2180 2190 2200
QAKMKDLSAR FSEASHKHKE TLAKMEELKT KVELFENLSE KLQTFLETKT
2210 2220 2230 2240 2250
QALTEVDVPG KDVTELSQYM QESTSEFLEH KKHLEVLHSL LKEISSHGLP
2260 2270 2280 2290 2300
SDKALVLEKT NNLSKKFKEM EDTIKEKKEA VTSCQEQLDA FQVLVKSLKS
2310 2320 2330 2340 2350
WIKETTKKVP IVQPSFGAED LGKSLEDTKK LQEKWSLKTP EIQKVNNSGI
2360 2370 2380 2390 2400
SLCNLISAVT TPAKAIAAVK SGGAVLNGEG TATNTEEFWA NKGLTSIKKD
2410 2420 2430 2440 2450
MTDISHGYED LGLLLKDKIA ELNTKLSKLQ KAQEESSAMM QWLQKMNKTA
2460 2470 2480 2490 2500
TKWQQTPAPT DTEAVKTQVE QNKSFEAELK QNVNKVQELK DKLTELLEEN
2510 2520 2530 2540 2550
PDTPEAPRWK QMLTEIDSKW QELNQLTIDR QQKLEESSNN LTQFQTVEAQ
2560 2570 2580 2590 2600
LKQWLVEKEL MVSVLGPLSI DPNMLNTQRQ QVQILLQEFA TRKPQYEQLT
2610 2620 2630 2640 2650
AAGQGILSRP GEDPSLRGIV KEQLAAVTQK WDSLTGQLSD RCDWIDQAIV
2660 2670 2680 2690 2700
KSTQYQSLLR SLSDKLSDLD NKLSSSLAVS THPDAMNQQL ETAQKMKQEI
2710 2720 2730 2740 2750
QQEKKQIKVA QALCEDLSAL VKEEYLKAEL SRQLEGILKS FKDVEQKAEN
2760 2770 2780 2790 2800
HVQHLQSACA SSHQFQQMSR DFQAWLDTKK EEQNKSHPIS AKLDVLESLI
2810 2820 2830 2840 2850
KDHKDFSKTL TAQSHMYEKT IAEGENLLLK TQGSEKAALQ LQLNTIKTNW
2860 2870 2880 2890 2900
DTFNKQVKER ENKLKESLEK ALKYKEQVET LWPWIDKCQN NLEEIKFCLD
2910 2920 2930 2940 2950
PAEGENSIAK LKSLQKEMDQ HFGMVELLNN TANSLLSVCE IDKEVVTDEN
2960 2970 2980 2990 3000
KSLIQKVDMV TEQLHSKKFC LENMTQKFKE FQEVSKESKR QLQCAKEQLD
3010 3020 3030 3040 3050
IHDSLGSQAY SNKYLTMLQT QQKSLQALKH QVDLAKRLAQ DLVVEASDSK
3060 3070 3080 3090 3100
GTSDVLLQVE TIAQEHSTLS QQVDEKCSFL ETKLQGIGHF QNTIREMFSQ
3110 3120 3130 3140 3150
FAEFDDELDS MAPVGRDAET LQKQKETIKA FLKKLEALMA SNDNANKTCK
3160 3170 3180 3190 3200
MMLATEETSP DLVGIKRDLE ALSKQCNKLL DRAQAREEQV EGTIKRLEEF
3210 3220 3230 3240 3250
YSKLKEFSIL LQKAEEHEES QGPVGMETET INQQLNMFKV FQKEEIEPLQ
3260 3270 3280 3290 3300
GKQQDVNWLG QGLIQSAAKS TSTQGLEHDL DDVNARWKTL NKKVAQRAAQ
3310 3320 3330 3340 3350
LQEALLHCGR FQDALESLLS WMVDTEELVA NQKPPSAEFK VVKAQIQEQK
3360 3370 3380 3390 3400
LLQRLLDDRK STVEVIKREG EKIATTAEPA DKVKILKQLS LLDSRWEALL
3410 3420 3430 3440 3450
NKAETRNRQL EGISVVAQQF HETLEPLNEW LTTIEKRLVN CEPIGTQASK
3460 3470 3480 3490 3500
LEEQIAQHKA LEDDIINHNK HLHQAVSIGQ SLKVLSSRED KDMVQSKLDF
3510 3520 3530 3540 3550
SQVWYIEIQE KSHSRSELLQ QALCNAKIFG EDEVELMNWL NEVHDKLSKL
3560 3570 3580 3590 3600
SVQDYSTEGL WKQQSELRVL QEDILLRKQN VDQALLNGLE LLKQTTGDEV
3610 3620 3630 3640 3650
LIIQDKLEAI KARYKDITKL STDVAKTLEQ ALQLARRLHS THEELCTWLD
3660 3670 3680 3690 3700
KVEVELLSYE TQVLKGEEAS QAQMRPKELK KEAKNNKALL DSLNEVSSAL
3710 3720 3730 3740 3750
LELVPWRARE GLEKMVAEDN ERYRLVSDTI TQKVEEIDAA ILRSQQFDQA
3760 3770 3780 3790 3800
ADAELSWITE TEKKLMSLGD IRLEQDQTSA QLQVQKTFTM EILRHKDIID
3810 3820 3830 3840 3850
DLVKSGHKIM TACSEEEKQS MKKKLDKVLK NYDTICQINS ERYLQLERAQ
3860 3870 3880 3890 3900
SLVNQFWETY EELWPWLTET QSIISQLPAP ALEYETLRQQ QEEHRQLREL
3910 3920 3930 3940 3950
IAEHKPHIDK MNKTGPQLLE LSPGEGFSIQ EKYVAADTLY SQIKEDVKKR
3960 3970 3980 3990 4000
AVALDEAISQ STQFHDKIDQ ILESLERIVE RLRQPPSISA EVEKIKEQIS
4010 4020 4030 4040 4050
ENKNVSVDME KLQPLYETLK QRGEEMIARS GGTDKDISAK AVQDKLDQMV
4060 4070 4080 4090 4100
FIWENIHTLV EEREAKLLDV MELAEKFWCD HMSLIVTIKD TQDFIRDLED
4110 4120 4130 4140 4150
PGIDPSVVKQ QQEAAETIRE EIDGLQEELD IVINLGSELI AACGEPDKPI
4160 4170 4180 4190 4200
VKKSIDELNS AWDSLNKAWK DRIDKLEEAM QAAVQYQDGL QAVFDWVDIA
4210 4220 4230 4240 4250
GGKLASMSPI GTDLETVKQQ IEELKQFKSE AYQQQIEMER LNHQAELLLK
4260 4270 4280 4290 4300
KVTEESDKHT VQDPLMELKL IWDSLEERII NRQHKLEGAL LALGQFQHAL
4310 4320 4330 4340 4350
DELLAWLTHT EGLLSEQKPV GGDPKAIEIE LAKHHVLQND VLAHQSTVEA
4360 4370 4380 4390 4400
VNKAGNDLIE SSAGEEASNL QNKLEVLNQR WQNVLEKTEQ RKQQLDGALR
4410 4420 4430 4440 4450
QAKGFHGEIE DLQQWLTDTE RHLLASKPLG GLPETAKEQL NVHMEVCAAF
4460 4470 4480 4490 4500
EAKEETYKSL MQKGQQMLAR CPKSAETNID QDINNLKEKW ESVETKLNER
4510 4520 4530 4540 4550
KTKLEEALNL AMEFHNSLQD FINWLTQAEQ TLNVASRPSL ILDTVLFQID
4560 4570 4580 4590 4600
EHKVFANEVN SHREQIIELD KTGTHLKYFS QKQDVVLIKN LLISVQSRWE
4610 4620 4630 4640 4650
KVVQRLVERG RSLDDARKRA KQFHEAWSKL MEWLEESEKS LDSELEIAND
4660 4670 4680 4690 4700
PDKIKTQLAQ HKEFQKSLGA KHSVYDTTNR TGRSLKEKTS LADDNLKLDD
4710 4720 4730 4740 4750
MLSELRDKWD TICGKSVERQ NKLEEALLFS GQFTDALQAL IDWLYRVEPQ
4760 4770 4780 4790 4800
LAEDQPVHGD IDLVMNLIDN HKAFQKELGK RTSSVQALKR SARELIEGSR
4810 4820 4830 4840 4850
DDSSWVKVQM QELSTRWETV CALSISKQTR LEAALRQAEE FHSVVHALLE
4860 4870 4880 4890 4900
WLAEAEQTLR FHGVLPDDED ALRTLIDQHK EFMKKLEEKR AELNKATTMG
4910 4920 4930 4940 4950
DTVLAICHPD SITTIKHWIT IIRARFEEVL AWAKQHQQRL ASALAGLIAK
4960 4970 4980 4990 5000
QELLEALLAW LQWAETTLTD KDKEVIPQEI EEVKALIAEH QTFMEEMTRK
5010 5020 5030 5040 5050
QPDVDKVTKT YKRRAADPSS LQSHIPVLDK GRAGRKRFPA SSLYPSGSQT
5060 5070 5080 5090 5100
QIETKNPRVN LLVSKWQQVW LLALERRRKL NDALDRLEEL REFANFDFDI
5110 5120 5130 5140 5150
WRKKYMRWMN HKKSRVMDFF RRIDKDQDGK ITRQEFIDGI LSSKFPTSRL
5160 5170 5180 5190 5200
EMSAVADIFD RDGDGYIDYY EFVAALHPNK DAYKPITDAD KIEDEVTRQV
5210 5220 5230 5240 5250
AKCKCAKRFQ VEQIGDNKYR FFLGNQFGDS QQLRLVRILR STVMVRVGGG
5260 5270 5280 5290 5300
WMALDEFLVK NDPCRAKGRT NMELREKFIL ADGASQGMAA FRPRGRRSRP
5310 5320 5330 5340 5350
SSRGASPNRS TSVSSQAAQA ASPQVPATTT PKILHPLTRN YGKPWLTNSK
5360 5370 5380 5390 5400
MSTPCKAAEC SDFPVPSAEG TPIQGSKLRL PGYLSGKGFH SGEDSGLITT
5410 5420 5430 5440 5450
AAARVRTQFA DSKKTPSRPG SRAGSKAGSR ASSRRGSDAS DFDISEIQSV
5460 5470 5480 5490
CSDVETVPQT HRPTPRAGSR PSTAKPSKIP TPQRKSPASK LDKSSKR
Length:5,497
Mass (Da):629,787
Last modified:October 29, 2014 - v3
Checksum:iEBB46088AF623DED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL096710 Genomic DNA. No translation available.
AL137008 Genomic DNA. No translation available.
AL512422 Genomic DNA. No translation available.
AL512448 Genomic DNA. No translation available.
AL590005 Genomic DNA. No translation available.
AL590037 Genomic DNA. No translation available.
KF458172 Genomic DNA. No translation available.
RefSeqiNP_899236.1. NM_183380.3.
UniGeneiHs.604915.
Hs.669931.
Hs.728928.
Hs.735651.

Genome annotation databases

EnsembliENST00000421834; ENSP00000400883; ENSG00000151914.
GeneIDi667.
UCSCiuc021zaz.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL096710 Genomic DNA. No translation available.
AL137008 Genomic DNA. No translation available.
AL512422 Genomic DNA. No translation available.
AL512448 Genomic DNA. No translation available.
AL590005 Genomic DNA. No translation available.
AL590037 Genomic DNA. No translation available.
KF458172 Genomic DNA. No translation available.
RefSeqiNP_899236.1. NM_183380.3.
UniGeneiHs.604915.
Hs.669931.
Hs.728928.
Hs.735651.

3D structure databases

ProteinModelPortaliE9PHM6.
SMRiE9PHM6. Positions 31-255, 583-795.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000244364.

Proteomic databases

EPDiE9PHM6.
PaxDbiE9PHM6.
PeptideAtlasiE9PHM6.
PRIDEiE9PHM6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000421834; ENSP00000400883; ENSG00000151914.
GeneIDi667.
UCSCiuc021zaz.3. human.

Organism-specific databases

CTDi667.
HGNCiHGNC:1090. DST.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IQBP. Eukaryota.
ENOG410XP41. LUCA.
GeneTreeiENSGT00760000119163.

Miscellaneous databases

ChiTaRSiDST. human.
GenomeRNAii667.

Gene expression databases

BgeeiE9PHM6.
ExpressionAtlasiE9PHM6. baseline and differential.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
1.10.418.10. 2 hits.
3.30.920.20. 1 hit.
InterProiIPR001589. Actinin_actin-bd_CS.
IPR001715. CH-domain.
IPR029926. Dystonin.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR003108. GAS_dom.
IPR018159. Spectrin/alpha-actinin.
IPR002017. Spectrin_repeat.
[Graphical view]
PANTHERiPTHR11915:SF38. PTHR11915:SF38. 5 hits.
PfamiPF00307. CH. 2 hits.
PF13499. EF-hand_7. 1 hit.
PF02187. GAS2. 1 hit.
PF00435. Spectrin. 21 hits.
[Graphical view]
SMARTiSM00033. CH. 2 hits.
SM00054. EFh. 2 hits.
SM00243. GAS2. 1 hit.
SM00150. SPEC. 30 hits.
[Graphical view]
SUPFAMiSSF143575. SSF143575. 1 hit.
SSF47473. SSF47473. 1 hit.
SSF47576. SSF47576. 1 hit.
PROSITEiPS00019. ACTININ_1. 1 hit.
PS00020. ACTININ_2. 1 hit.
PS50021. CH. 2 hits.
PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS51460. GAR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
  6. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiE9PHM6_HUMAN
AccessioniPrimary (citable) accession number: E9PHM6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 29, 2014
Last modified: July 6, 2016
This is version 40 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.