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E9PHI8

- E9PHI8_HUMAN

UniProt

E9PHI8 - E9PHI8_HUMAN

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Protein
Submitted name:

Serine/threonine-protein kinase Nek11

Gene

NEK11

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. protein serine/threonine kinase activity Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

SignaLinkiE9PHI8.

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase Nek11Imported
Gene namesi
Name:NEK11Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:18593. NEK11.

Expressioni

Gene expression databases

BgeeiE9PHI8.
ExpressionAtlasiE9PHI8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PHI8.
SMRiE9PHI8. Positions 28-275.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118997.
KOiK08857.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PHI8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLKFQEAAKC VSGSTAISTY PKTLIARRYV LQQKLGSGSF GTVYLVSDKK
60 70 80 90 100
AKRGEELKVL KEISVGELNP NETVQANLEA QLLSKLDHPA IVKFHASFVE
110 120 130 140 150
QDNFCIITEY CEGRDLDDKI QEYKQAGKIF PENQIIEWFI QLLLGVDYMH
160 170 180 190 200
ERRILHRDLK SKNVFLKNNL LKIGDFGVSR LLMGSCDLAT TLTGTPHYMS
210 220 230 240 250
PEALKHQGYD TKSDIWQKRI HLQTLRALSE VQKMTPRERM RLRKLQAADE
260 270 280 290 300
KARKLKKIVE EKYEENSKRM QELRSRNFQQ LSVDVLHEKT HLKGMEEKEE
310 320 330 340 350
QPEGRLSCSP QDEDEERWQG REEESDEPTL ENLPESQPIP SMDLHELESI
360 370 380 390 400
VEDATSDLGY HEIPEDPLVA EEYYADAFDS YCEESDEEEE EIALERPEKE
410 420 430 440 450
IRNEGSQPAY RTNQQDSDIE ALARCLENVL GCTSLDTKTI TTMAEDMSPG
460 470 480 490 500
PPIFNSVMAR TKMKRMRESA MQKLGTEVFE EVYNYLKRAR HQNASEAEIR
510 520 530 540
ECLEKVVPQA SDCFEVDQLL YFEEQLLITM GKEPTLQNHL
Length:540
Mass (Da):62,285
Last modified:June 28, 2011 - v1
Checksum:i26F20408DBA56F04
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC010210 Genomic DNA. No translation available.
AC055733 Genomic DNA. No translation available.
AC083908 Genomic DNA. No translation available.
AC116424 Genomic DNA. No translation available.
AC121332 Genomic DNA. No translation available.
RefSeqiXP_005247842.1. XM_005247785.1.
UniGeneiHs.657336.

Genome annotation databases

EnsembliENST00000510769; ENSP00000421549; ENSG00000114670.
GeneIDi79858.
KEGGihsa:79858.
UCSCiuc011bll.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC010210 Genomic DNA. No translation available.
AC055733 Genomic DNA. No translation available.
AC083908 Genomic DNA. No translation available.
AC116424 Genomic DNA. No translation available.
AC121332 Genomic DNA. No translation available.
RefSeqi XP_005247842.1. XM_005247785.1.
UniGenei Hs.657336.

3D structure databases

ProteinModelPortali E9PHI8.
SMRi E9PHI8. Positions 28-275.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000510769 ; ENSP00000421549 ; ENSG00000114670 .
GeneIDi 79858.
KEGGi hsa:79858.
UCSCi uc011bll.2. human.

Organism-specific databases

CTDi 79858.
HGNCi HGNC:18593. NEK11.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000118997.
KOi K08857.

Enzyme and pathway databases

SignaLinki E9PHI8.

Miscellaneous databases

GenomeRNAii 79858.
NextBioi 35502060.

Gene expression databases

Bgeei E9PHI8.
ExpressionAtlasi E9PHI8. baseline and differential.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PHI8_HUMAN
AccessioniPrimary (citable) accession number: E9PHI8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: October 29, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3