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Protein
Submitted name:

C-Jun-amino-terminal kinase-interacting protein 3

Gene

MAPK8IP3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
C-Jun-amino-terminal kinase-interacting protein 3Imported
Gene namesi
Name:MAPK8IP3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:6884. MAPK8IP3.

PTM / Processingi

Proteomic databases

MaxQBiE9PFH7.
PaxDbiE9PFH7.
PeptideAtlasiE9PFH7.
PRIDEiE9PFH7.

Expressioni

Gene expression databases

BgeeiENSG00000138834.
ExpressionAtlasiE9PFH7. baseline and differential.
GenevisibleiE9PFH7. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000250894.

Structurei

3D structure databases

ProteinModelPortaliE9PFH7.
SMRiE9PFH7. Positions 427-480.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini29 – 184156Jnk-SapK_ap_NInterPro annotationAdd
BLAST
Domaini408 – 47871JIP_LZIIInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili66 – 167102Sequence analysisAdd
BLAST
Coiled coili442 – 49049Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2077. Eukaryota.
ENOG410XQ19. LUCA.
GeneTreeiENSGT00670000097546.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR032486. JIP_LZII.
IPR019143. JNK/Rab-associated_protein-1_N.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF16471. JIP_LZII. 1 hit.
PF09744. Jnk-SapK_ap_N. 1 hit.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PFH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMEIQMDEGG GVVVYQDDYC SGSVMSERVS GLAGSIYREF ERLIHCYDEE
60 70 80 90 100
VVKELMPLVV NVLENLDSVL SENQEHEVEL ELLREDNEQL LTQYEREKAL
110 120 130 140 150
RRQAEEKFIE FEDALEQEKK ELQIQVEHYE FQTRQLELKA KNYADQISRL
160 170 180 190 200
EERESEMKKE YNALHQRHTE MIQTYVEHIE RSKMQQVGGN SQTESSLPGR
210 220 230 240 250
RKERPTSLNV FPLADGTVRA QIGGKLVPAG DHWHLSDLGQ LQSSSSYQCP
260 270 280 290 300
QDEMSESGQS SAAATPSTTG TKSNTPTSSV PSAAVTPLNE SLQPLGDYGV
310 320 330 340 350
GSKNSKRARE KRDSRNMEVQ VTQEMRNVSI GMGSSDEWSD VQDIIDSTPE
360 370 380 390 400
LDMCPETRLD RTGSSPTQGI VNKAFGINTD SLYHELSTAG SEVIGDVDEG
410 420 430 440 450
ADLLGEFSGM GKEVGNLLLE NSQLLETKNA LNVVKNDLIA KVDQLSGEQE
460 470 480 490 500
VLRGELEAAK QAKVKLENRI KELEEELKRV KSEAIIARRE PKEEAEDVSS
510 520 530 540 550
YLCTESDKIP MAQRRRFTRV EMARVLMERN QYKERLMELQ EAVRWTEMIR
560 570 580 590 600
ASREHPSVQE KKKSTIWQFF SRLFSSSSSP PPAKRPYPSV NIHYKSPTTA
610 620 630 640 650
GFSQRRNHAM CPISAGSRPL EFFPDDDCTS SARREQKREQ YRQVREHVRN
660 670 680 690 700
DDGRLQACGW SLPAKYKQLS PNGGQEDTRM KNVPVPVYCR PLVEKDPTMK
710 720 730 740 750
LWCAAGVNLS GWRPNEDDAG NGVKPAPGRD PLTCDREGDG EPKSAHTSPE
760 770 780 790 800
KKKAKELPEM DATSSRVWIL TSTLTTSKVV IIDANQPGTV VDQFTVCNAH
810 820 830 840 850
VLCISSIPAA SDSDYPPGEM FLDSDVNPED PGADGVLAGI TLVGCATRCN
860 870 880 890 900
VPRSNCSSRG DTPVLDKGQG EVATIANGKV NPSQSTEEAT EATEVPDPGP
910 920 930 940 950
SEPETATLRP GPLTEHVFTD PAPTPSSGPQ PGSENGPEPD SSSTRPEPEP
960 970 980 990 1000
SGDPTGAGSS AAPTMWLGAQ NGWLYVHSAV ANWKKCLHSI KLKDSVLSLV
1010 1020 1030 1040 1050
HVKGRVLVAL ADGTLAIFHR GEDGQWDLSN YHLMDLGHPH HSIRCMAVVY
1060 1070 1080 1090 1100
DRVWCGYKNK VHVIQPKTMQ IEKSFDAHPR RESQVRQLAW IGDGVWVSIR
1110 1120 1130 1140 1150
LDSTLRLYHA HTHQHLQDVD IEPYVSKMLG TGKLGFSFVR ITALLVAGSR
1160 1170 1180 1190 1200
LWVGTGNGVV ISIPLTETVV LHRGQLLGLR ANKTSPTSGE GARPGGIIHV
1210 1220 1230 1240 1250
YGDDSSDRAA SSFIPYCSMA QAQLCFHGHR DAVKFFVSVP GNVLATLNGS
1260 1270 1280 1290 1300
VLDSPAEGPG PAAPASEVEG QKLRNVLVLS GGEGYIDFRI GDGEDDETEE
1310 1320 1330
GAGDMSQVKP VLSKAERSHI IVWQVSYTPE
Length:1,330
Mass (Da):146,677
Last modified:April 5, 2011 - v1
Checksum:i4EEF88EF17E0F104
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012180 Genomic DNA. No translation available.
AL031710 Genomic DNA. No translation available.
AL031717 Genomic DNA. No translation available.
RefSeqiNP_001035529.1. NM_001040439.1.
UniGeneiHs.207763.

Genome annotation databases

EnsembliENST00000356010; ENSP00000348290; ENSG00000138834.
GeneIDi23162.
UCSCiuc059ozt.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012180 Genomic DNA. No translation available.
AL031710 Genomic DNA. No translation available.
AL031717 Genomic DNA. No translation available.
RefSeqiNP_001035529.1. NM_001040439.1.
UniGeneiHs.207763.

3D structure databases

ProteinModelPortaliE9PFH7.
SMRiE9PFH7. Positions 427-480.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000250894.

Proteomic databases

MaxQBiE9PFH7.
PaxDbiE9PFH7.
PeptideAtlasiE9PFH7.
PRIDEiE9PFH7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000356010; ENSP00000348290; ENSG00000138834.
GeneIDi23162.
UCSCiuc059ozt.1. human.

Organism-specific databases

CTDi23162.
HGNCiHGNC:6884. MAPK8IP3.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2077. Eukaryota.
ENOG410XQ19. LUCA.
GeneTreeiENSGT00670000097546.

Miscellaneous databases

ChiTaRSiMAPK8IP3. human.
GenomeRNAii23162.

Gene expression databases

BgeeiENSG00000138834.
ExpressionAtlasiE9PFH7. baseline and differential.
GenevisibleiE9PFH7. HS.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR032486. JIP_LZII.
IPR019143. JNK/Rab-associated_protein-1_N.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF16471. JIP_LZII. 1 hit.
PF09744. Jnk-SapK_ap_N. 1 hit.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE9PFH7_HUMAN
AccessioniPrimary (citable) accession number: E9PFH7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 7, 2016
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.