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E9PFE2

- E9PFE2_HUMAN

UniProt

E9PFE2 - E9PFE2_HUMAN

Protein
Submitted name:

General transcription factor II-I repeat domain-containing protein 1

Gene

GTF2IRD1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Submitted name:
    General transcription factor II-I repeat domain-containing protein 1Imported
    Gene namesi
    Name:GTF2IRD1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 7

    Organism-specific databases

    HGNCiHGNC:4661. GTF2IRD1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: HPA
    2. nucleus Source: HPA

    Expressioni

    Gene expression databases

    ArrayExpressiE9PFE2.
    BgeeiE9PFE2.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PFE2.
    SMRiE9PFE2. Positions 128-203, 351-427, 565-650, 687-775, 787-865.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK03121.
    OrthoDBiEOG7ZSHS4.

    Family and domain databases

    Gene3Di3.90.1460.10. 5 hits.
    InterProiIPR004212. GTF2I.
    IPR016659. TF_II-I.
    [Graphical view]
    PfamiPF02946. GTF2I. 5 hits.
    [Graphical view]
    PIRSFiPIRSF016441. TF_II-I. 1 hit.
    SUPFAMiSSF117773. SSF117773. 5 hits.
    PROSITEiPS51139. GTF2I. 5 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9PFE2-1 [UniParc]FASTAAdd to Basket

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    MALLGKRCDV PTNGCGPDRW NSAFTRKDEI ITSLVSALDS MCSALSKLNA    50
    EVACVAVHDE SAFVVGTEKG RMFLNARKEL QSDFLRFCRG PPWKDPEAEH 100
    PKKVQRGEGG GRSLPRSSLE HGSDVYLLRK MVEEVFDVLY SEALGRASVV 150
    PLPYERLLRE PGLLAVQGLP EGLAFRRPAE YDPKALMAIL EHSHRIRFKL 200
    KRPLEDGGRD SKALVELNGV SLIPKGSRDC GLHGQAPKVP PQDLPPTATS 250
    SSMASFLYST ALPNHAIREL KQEAPSCPLA PSDLGLSRPM PEPKATGAQD 300
    FSDCCGQKPT GPGGPLIQNV HASKRILFSI VHDKSEKWDA FIKETEDINT 350
    LRECVQILFN SRYAEALGLD HMVPVPYRKI ACDPEAVEIV GIPDKIPFKR 400
    PCTYGVPKLK RILEERHSIH FIIKRMFDER IFTGNKFTKD TTKLEPASPP 450
    EDTSAEVSRA TVLDLAGNAR SDKGSMSEDC GPGTSGELGG LRPIKIEPED 500
    LDIIQVTVPD PSPTSEEMTD SMPGHLPSED SGYGMEMLTD KGLSEDARPE 550
    ERPVEDSHGD VIRPLRKQVE LLFNTRYAKA IGISEPVKVP YSKFLMHPEE 600
    LFVVGLPEGI SLRRPNCFGI AKLRKILEAS NSIQFVIKRP ELLTEGVKEP 650
    IMDSQERDSG DPLVDESLKR QGFQENYDAR LSRIDIANTL REQVQDLFNK 700
    KYGEALGIKY PVQVPYKRIK SNPGSVIIEG LPPGIPFRKP CTFGSQNLER 750
    ILAVADKIKF TVTRPFQGLI PKPDEDDANR LGEKVILREQ VKELFNEKYG 800
    EALGLNRPVL VPYKLIRDSP DAVEVTGLPD DIPFRNPNTY DIHRLEKILK 850
    AREHVRMVII NQLQPFAEIC NDAKVPAKDS SIPKRKRKRV SEGNSVSSSS 900
    SSSSSSSSNP DSVASANQIS LVVKLHRFGL RHSSLWPSPL CLAGPSTLGC 950
    GPRGRGGTGL 960
    Length:960
    Mass (Da):106,049
    Last modified:April 5, 2011 - v1
    Checksum:iE08A2EF95D7859D2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004851 Genomic DNA. No translation available.
    AC005015 Genomic DNA. No translation available.
    AC211433 Genomic DNA. No translation available.
    KF495976 Genomic DNA. No translation available.
    RefSeqiXP_005250777.1. XM_005250720.2.
    XP_006716245.1. XM_006716182.1.
    XP_006716246.1. XM_006716183.1.
    UniGeneiHs.647056.

    Genome annotation databases

    EnsembliENST00000476977; ENSP00000418383; ENSG00000006704.
    GeneIDi9569.
    KEGGihsa:9569.
    UCSCiuc003uar.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004851 Genomic DNA. No translation available.
    AC005015 Genomic DNA. No translation available.
    AC211433 Genomic DNA. No translation available.
    KF495976 Genomic DNA. No translation available.
    RefSeqi XP_005250777.1. XM_005250720.2.
    XP_006716245.1. XM_006716182.1.
    XP_006716246.1. XM_006716183.1.
    UniGenei Hs.647056.

    3D structure databases

    ProteinModelPortali E9PFE2.
    SMRi E9PFE2. Positions 128-203, 351-427, 565-650, 687-775, 787-865.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000476977 ; ENSP00000418383 ; ENSG00000006704 .
    GeneIDi 9569.
    KEGGi hsa:9569.
    UCSCi uc003uar.1. human.

    Organism-specific databases

    CTDi 9569.
    HGNCi HGNC:4661. GTF2IRD1.
    GenAtlasi Search...

    Phylogenomic databases

    KOi K03121.
    OrthoDBi EOG7ZSHS4.

    Miscellaneous databases

    GenomeRNAii 9569.
    NextBioi 35501830.

    Gene expression databases

    ArrayExpressi E9PFE2.
    Bgeei E9PFE2.

    Family and domain databases

    Gene3Di 3.90.1460.10. 5 hits.
    InterProi IPR004212. GTF2I.
    IPR016659. TF_II-I.
    [Graphical view ]
    Pfami PF02946. GTF2I. 5 hits.
    [Graphical view ]
    PIRSFi PIRSF016441. TF_II-I. 1 hit.
    SUPFAMi SSF117773. SSF117773. 5 hits.
    PROSITEi PS51139. GTF2I. 5 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of human chromosome 7."
      Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
      , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
      Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    5. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE9PFE2_HUMAN
    AccessioniPrimary (citable) accession number: E9PFE2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3