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E9PFE2

- E9PFE2_HUMAN

UniProt

E9PFE2 - E9PFE2_HUMAN

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Protein
Submitted name:

General transcription factor II-I repeat domain-containing protein 1

Gene

GTF2IRD1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
General transcription factor II-I repeat domain-containing protein 1Imported
Gene namesi
Name:GTF2IRD1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:4661. GTF2IRD1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: HPA
  2. nucleus Source: HPA
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE9PFE2.
ExpressionAtlasiE9PFE2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PFE2.
SMRiE9PFE2. Positions 128-203, 351-427, 565-650, 687-775, 787-865.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063863.
KOiK03121.
OrthoDBiEOG7ZSHS4.

Family and domain databases

Gene3Di3.90.1460.10. 5 hits.
InterProiIPR004212. GTF2I.
IPR016659. TF_II-I.
[Graphical view]
PfamiPF02946. GTF2I. 5 hits.
[Graphical view]
PIRSFiPIRSF016441. TF_II-I. 1 hit.
SUPFAMiSSF117773. SSF117773. 5 hits.
PROSITEiPS51139. GTF2I. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PFE2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALLGKRCDV PTNGCGPDRW NSAFTRKDEI ITSLVSALDS MCSALSKLNA
60 70 80 90 100
EVACVAVHDE SAFVVGTEKG RMFLNARKEL QSDFLRFCRG PPWKDPEAEH
110 120 130 140 150
PKKVQRGEGG GRSLPRSSLE HGSDVYLLRK MVEEVFDVLY SEALGRASVV
160 170 180 190 200
PLPYERLLRE PGLLAVQGLP EGLAFRRPAE YDPKALMAIL EHSHRIRFKL
210 220 230 240 250
KRPLEDGGRD SKALVELNGV SLIPKGSRDC GLHGQAPKVP PQDLPPTATS
260 270 280 290 300
SSMASFLYST ALPNHAIREL KQEAPSCPLA PSDLGLSRPM PEPKATGAQD
310 320 330 340 350
FSDCCGQKPT GPGGPLIQNV HASKRILFSI VHDKSEKWDA FIKETEDINT
360 370 380 390 400
LRECVQILFN SRYAEALGLD HMVPVPYRKI ACDPEAVEIV GIPDKIPFKR
410 420 430 440 450
PCTYGVPKLK RILEERHSIH FIIKRMFDER IFTGNKFTKD TTKLEPASPP
460 470 480 490 500
EDTSAEVSRA TVLDLAGNAR SDKGSMSEDC GPGTSGELGG LRPIKIEPED
510 520 530 540 550
LDIIQVTVPD PSPTSEEMTD SMPGHLPSED SGYGMEMLTD KGLSEDARPE
560 570 580 590 600
ERPVEDSHGD VIRPLRKQVE LLFNTRYAKA IGISEPVKVP YSKFLMHPEE
610 620 630 640 650
LFVVGLPEGI SLRRPNCFGI AKLRKILEAS NSIQFVIKRP ELLTEGVKEP
660 670 680 690 700
IMDSQERDSG DPLVDESLKR QGFQENYDAR LSRIDIANTL REQVQDLFNK
710 720 730 740 750
KYGEALGIKY PVQVPYKRIK SNPGSVIIEG LPPGIPFRKP CTFGSQNLER
760 770 780 790 800
ILAVADKIKF TVTRPFQGLI PKPDEDDANR LGEKVILREQ VKELFNEKYG
810 820 830 840 850
EALGLNRPVL VPYKLIRDSP DAVEVTGLPD DIPFRNPNTY DIHRLEKILK
860 870 880 890 900
AREHVRMVII NQLQPFAEIC NDAKVPAKDS SIPKRKRKRV SEGNSVSSSS
910 920 930 940 950
SSSSSSSSNP DSVASANQIS LVVKLHRFGL RHSSLWPSPL CLAGPSTLGC
960
GPRGRGGTGL
Length:960
Mass (Da):106,049
Last modified:April 5, 2011 - v1
Checksum:iE08A2EF95D7859D2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC004851 Genomic DNA. No translation available.
AC005015 Genomic DNA. No translation available.
AC211433 Genomic DNA. No translation available.
KF495976 Genomic DNA. No translation available.
RefSeqiXP_005250777.1. XM_005250720.2.
XP_006716245.1. XM_006716182.1.
XP_006716246.1. XM_006716183.1.
UniGeneiHs.647056.

Genome annotation databases

EnsembliENST00000476977; ENSP00000418383; ENSG00000006704.
GeneIDi9569.
KEGGihsa:9569.
UCSCiuc003uar.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC004851 Genomic DNA. No translation available.
AC005015 Genomic DNA. No translation available.
AC211433 Genomic DNA. No translation available.
KF495976 Genomic DNA. No translation available.
RefSeqi XP_005250777.1. XM_005250720.2.
XP_006716245.1. XM_006716182.1.
XP_006716246.1. XM_006716183.1.
UniGenei Hs.647056.

3D structure databases

ProteinModelPortali E9PFE2.
SMRi E9PFE2. Positions 128-203, 351-427, 565-650, 687-775, 787-865.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000476977 ; ENSP00000418383 ; ENSG00000006704 .
GeneIDi 9569.
KEGGi hsa:9569.
UCSCi uc003uar.1. human.

Organism-specific databases

CTDi 9569.
HGNCi HGNC:4661. GTF2IRD1.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00530000063863.
KOi K03121.
OrthoDBi EOG7ZSHS4.

Miscellaneous databases

GenomeRNAii 9569.
NextBioi 35501830.

Gene expression databases

Bgeei E9PFE2.
ExpressionAtlasi E9PFE2. baseline and differential.

Family and domain databases

Gene3Di 3.90.1460.10. 5 hits.
InterProi IPR004212. GTF2I.
IPR016659. TF_II-I.
[Graphical view ]
Pfami PF02946. GTF2I. 5 hits.
[Graphical view ]
PIRSFi PIRSF016441. TF_II-I. 1 hit.
SUPFAMi SSF117773. SSF117773. 5 hits.
PROSITEi PS51139. GTF2I. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PFE2_HUMAN
AccessioniPrimary (citable) accession number: E9PFE2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3