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Protein
Submitted name:

Forkhead box protein P1

Gene

FOXP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi467 – 540Fork-headPROSITE-ProRule annotationAdd BLAST74

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscriptionSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box protein P1Imported
Gene namesi
Name:FOXP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:3823. FOXP1.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000114861.

PTM / Processingi

Proteomic databases

MaxQBiE9PFD3.
PaxDbiE9PFD3.
PeptideAtlasiE9PFD3.
PRIDEiE9PFD3.

Expressioni

Gene expression databases

BgeeiENSG00000114861.
ExpressionAtlasiE9PFD3. baseline and differential.
GenevisibleiE9PFD3. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000318902.

Structurei

3D structure databases

ProteinModelPortaliE9PFD3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini467 – 540Fork-head DNA-bindingInterPro annotationAdd BLAST74

Phylogenomic databases

eggNOGiKOG4385. Eukaryota.
COG5025. LUCA.
GeneTreeiENSGT00800000124014.
OMAiNNIPLYT.
PhylomeDBiE9PFD3.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR001766. Fork_head_dom.
IPR032354. FOXP-CC.
IPR030456. TF_fork_head_CS_2.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00250. Forkhead. 1 hit.
PF16159. FOXP-CC. 1 hit.
PRINTSiPR00053. FORKHEAD.
SMARTiView protein in SMART
SM00339. FH. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PFD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFQCVFSSSV LQPHSTSCLF KHLFYHSATP ASQKQPEPIY SKKTEIQRQT
60 70 80 90 100
VRAPFAKLFI FSALQVARQL LLQQQQQQQV SGLKSPKRND KQPALQVPVS
110 120 130 140 150
VAMMTPQVIT PQQMQQILQQ QVLSPQQLQV LLQQQQALML QQQQLQEFYK
160 170 180 190 200
KQQEQLQLQL LQQQHAGKQP KEQQQVATQQ LAFQQQLLQM QQLQQQHLLS
210 220 230 240 250
LQRQGLLTIQ PGQPALPLQP LAQGMIPTEL QQLWKEVTSA HTAEETTGNN
260 270 280 290 300
HSSLDLTTTC VSSSAPSKTS LIMNPHASTN GQLSVHTPKR ESLSHEEHPH
310 320 330 340 350
SHPLYGHGVC KWPGCEAVCE DFQSFLKHLN SEHALDDRST AQCRVQMQVV
360 370 380 390 400
QQLELQLAKD KERLQAMMTH LHVKSTEPKA APQPLNLVSS VTLSKSASEA
410 420 430 440 450
SPQSLPHTPT TPTAPLTPVT QGPSVITTTS MHTVGPIRRR YSDKYNVPIS
460 470 480 490 500
SADIAQNQEF YKNAEVRPPF TYASLIRQAI LESPEKQLTL NEIYNWFTRM
510 520 530 540 550
FAYFRRNAAT WKNAVRHNLS LHKCFVRVEN VKGAVWTVDE VEFQKRRPQK
560 570 580 590 600
ISGNPSLIKN MQSSHAYCTP LNAALQASMA ENSIPLYTTA SMGNPTLGNL
610 620 630 640 650
ASAIREELNG AMEHTNSNES DSSPGRSPMQ AVHPVHVKEE PLDPEEAEGP
660 670
LSLVTTANHS PDFDHDRDYE DEPVNEDME
Length:679
Mass (Da):76,314
Last modified:April 5, 2011 - v1
Checksum:i003F5DFCAEC01AB8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097632 Genomic DNA. No translation available.
AC097634 Genomic DNA. No translation available.
AC103586 Genomic DNA. No translation available.
AC104442 Genomic DNA. No translation available.
AC104645 Genomic DNA. No translation available.
AC138058 Genomic DNA. No translation available.
RefSeqiNP_001231744.1. NM_001244815.1.
UniGeneiHs.59368.

Genome annotation databases

EnsembliENST00000491238; ENSP00000420736; ENSG00000114861.
GeneIDi27086.
UCSCiuc003doj.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097632 Genomic DNA. No translation available.
AC097634 Genomic DNA. No translation available.
AC103586 Genomic DNA. No translation available.
AC104442 Genomic DNA. No translation available.
AC104645 Genomic DNA. No translation available.
AC138058 Genomic DNA. No translation available.
RefSeqiNP_001231744.1. NM_001244815.1.
UniGeneiHs.59368.

3D structure databases

ProteinModelPortaliE9PFD3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000318902.

Proteomic databases

MaxQBiE9PFD3.
PaxDbiE9PFD3.
PeptideAtlasiE9PFD3.
PRIDEiE9PFD3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000491238; ENSP00000420736; ENSG00000114861.
GeneIDi27086.
UCSCiuc003doj.4. human.

Organism-specific databases

CTDi27086.
HGNCiHGNC:3823. FOXP1.
OpenTargetsiENSG00000114861.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4385. Eukaryota.
COG5025. LUCA.
GeneTreeiENSGT00800000124014.
OMAiNNIPLYT.
PhylomeDBiE9PFD3.

Miscellaneous databases

ChiTaRSiFOXP1. human.
GenomeRNAii27086.

Gene expression databases

BgeeiENSG00000114861.
ExpressionAtlasiE9PFD3. baseline and differential.
GenevisibleiE9PFD3. HS.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR001766. Fork_head_dom.
IPR032354. FOXP-CC.
IPR030456. TF_fork_head_CS_2.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00250. Forkhead. 1 hit.
PF16159. FOXP-CC. 1 hit.
PRINTSiPR00053. FORKHEAD.
SMARTiView protein in SMART
SM00339. FH. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE9PFD3_HUMAN
AccessioniPrimary (citable) accession number: E9PFD3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 15, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.