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Protein

Isocitrate dehydrogenase [NAD] subunit, mitochondrial

Gene

IDH3G

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTricarboxylic acid cycleUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NAD] subunit, mitochondrialUniRule annotation
Gene namesi
Name:IDH3GImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000067829.18
HGNCiHGNC:5386 IDH3G

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MitochondrionUniRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000067829

PTM / Processingi

Proteomic databases

EPDiE9PF84
MaxQBiE9PF84
PeptideAtlasiE9PF84
PRIDEiE9PF84

Expressioni

Gene expression databases

BgeeiENSG00000067829
ExpressionAtlasiE9PF84 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PF84
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 285Iso_dhInterPro annotationAdd BLAST253

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Phylogenomic databases

eggNOGiKOG0784 Eukaryota
COG0473 LUCA
GeneTreeiENSGT00590000083091

Family and domain databases

InterProiView protein in InterPro
IPR019818 IsoCit/isopropylmalate_DH_CS
IPR004434 Isocitrate_DH_NAD
IPR024084 IsoPropMal-DH-like_dom
PfamiView protein in Pfam
PF00180 Iso_dh, 1 hit
SMARTiView protein in SMART
SM01329 Iso_dh, 1 hit
TIGRFAMsiTIGR00175 mito_nad_idh, 1 hit
PROSITEiView protein in PROSITE
PS00470 IDH_IMDH, 1 hit

Sequencei

Sequence statusi: Fragment.

E9PF84-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALKVLGAHE VPSRNIFSEQ TIPPSAKYGG RHTVTMIPGD GIGPELMLHV
60 70 80 90 100
KSVFRHACVP VDFEEVHVSS NADEEDIRNA IMAIRRNRVA LKGNIETNHN
110 120 130 140 150
LPPSHKSRNN ILRTSLDLYA NVIHCKSLPG VVTRHKDIDI LIVRENTEGE
160 170 180 190 200
YSSLEHESVA GVVESLKIIT KAKSLRIAEY AFKLAQESGR KKVTAVHKAN
210 220 230 240 250
IMKLGDGLFL QCCREVAARY PQITFENMIV DNTTMQLVSR PQQFDVMVMP
260 270 280
NLYGNIVNNV CAGLVGGPGL VAGANYGHVY AVFET
Length:285
Mass (Da):31,422
Last modified:April 5, 2011 - v1
Checksum:i81FC35CD370F1DC7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei285Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U52111 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000444450; ENSP00000401862; ENSG00000067829
UCSCiuc065bws.1 human

Similar proteinsi

Entry informationi

Entry nameiE9PF84_HUMAN
AccessioniPrimary (citable) accession number: E9PF84
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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