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Protein
Submitted name:

Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

Gene

HADH

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrialImported
Gene namesi
Name:HADHImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000138796.15.
HGNCiHGNC:4799. HADH.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000138796.

PTM / Processingi

Proteomic databases

EPDiE9PF18.

Expressioni

Gene expression databases

BgeeiENSG00000138796.
ExpressionAtlasiE9PF18. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 2733HCDH_NInterPro annotationAdd BLAST186
Domaini312 – 3893HCDHInterPro annotationAdd BLAST78

Phylogenomic databases

GeneTreeiENSGT00880000137923.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
InterProiView protein in InterPro
IPR006176. 3-OHacyl-CoA_DH_NAD-bd.
IPR006108. 3HC_DH_C.
IPR008927. 6-PGluconate_DH-like_C_sf.
IPR013328. 6PGD_dom2.
IPR036291. NAD(P)-bd_dom_sf.
PfamiView protein in Pfam
PF00725. 3HCDH. 1 hit.
PF02737. 3HCDH_N. 1 hit.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PF18-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRAGLEAPP PPCGVTGTPG ARGLQGRVGP RPQSLAFRGC PPRASSLPGS
60 70 80 90 100
PRCRRRCHTM AFVTRQFMRS VSSSSTASAS AKKIIVKHVT VIGGGLMGAG
110 120 130 140 150
IAQVAAATGH TVVLVDQTED ILAKSKKGIE ESLRKVAKKK FAENLKAGDE
160 170 180 190 200
FVEKTLSTIA TSTDAASVVH STDLVVEAIV ENLKVKNELF KRLDKFAAEH
210 220 230 240 250
TIFASNTSSL QITSIANATT RQDRFAGLHF FNPVPVMKLV EVIKTPMTSQ
260 270 280 290 300
KTFESLVDFS KALGKHPVSC KDTPGFIVNR LLVPYLMEAI RLYERDFQTC
310 320 330 340 350
GDSNSGLGFS LKGDASKEDI DTAMKLGAGY PMGPFELLDY VGLDTTKFIV
360 370 380 390
DGWHEMDAEN PLHQPSPSLN KLVAENKFGK KTGEGFYKYK
Length:390
Mass (Da):42,123
Last modified:June 7, 2017 - v2
Checksum:iA07F1CAC27704B7C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114733 Genomic DNA. No translation available.
AC118062 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000505878; ENSP00000425952; ENSG00000138796.
UCSCiuc003hyr.4. human.

Similar proteinsi

Entry informationi

Entry nameiE9PF18_HUMAN
AccessioniPrimary (citable) accession number: E9PF18
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: June 7, 2017
Last modified: November 22, 2017
This is version 61 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported