Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Abl interactor 2

Gene

ABI2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Abl interactor 2Imported
Gene namesi
Name:ABI2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:24011. ABI2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiE9PEZ7.
PaxDbiE9PEZ7.
PRIDEiE9PEZ7.

Expressioni

Gene expression databases

BgeeiE9PEZ7.
ExpressionAtlasiE9PEZ7. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000261017.

Structurei

3D structure databases

ProteinModelPortaliE9PEZ7.
SMRiE9PEZ7. Positions 1-155, 389-453.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini45 – 10763T-SNARE coiled-coil homologyInterPro annotationAdd
BLAST
Domaini396 – 45560SH3InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2546. Eukaryota.
ENOG410Y0MH. LUCA.
GeneTreeiENSGT00390000003756.

Family and domain databases

InterProiIPR028457. ABI.
IPR028454. Abi2.
IPR012849. Abl-interactor_HHR_dom.
IPR001452. SH3_domain.
IPR000727. T_SNARE_dom.
[Graphical view]
PANTHERiPTHR10460. PTHR10460. 2 hits.
PTHR10460:SF3. PTHR10460:SF3. 2 hits.
PfamiPF07815. Abi_HHR. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PEZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAELQMLLEE EIPGGRRALF DSYTNLERVA DYCENNYIQS ADKQRALEET
60 70 80 90 100
KAYTTQSLAS VAYLINTLAN NVLQMLDIQA SQLRRMESSI NHISQTVDIH
110 120 130 140 150
KEKVARREIG ILTTNKNTSR THKIIAPANL ERPVRYIRKP IDYTILDDIG
160 170 180 190 200
HGVKVSTQNM KMGGLPRTTP PTQKPPSPPM SGKGTLGSSG SSGGSHPSSR
210 220 230 240 250
SSSRENSGSG SVGVPIAVPT PSPPSVFPAP AGSAGTPPLP ATSASAPAPL
260 270 280 290 300
VPATVPSSTA PDAAAGGAQT LADGFTSPTP PVVSSTPPTG HPVQFYSMNR
310 320 330 340 350
PASRHTPPTI GGSLPYRRPP SITSQTSLQN QMNGGPFYSQ NPVSDTPPPP
360 370 380 390 400
PPVEEPVFDE SPPPPPPPED YEEEEAAVVE YSDPYAEEDP PWAPRSYLEK
410 420 430 440 450
VVAIYDYTKD KEDELSFQEG AIIYVIKKND DGWYEGVMNG VTGLFPGNYV

ESIMHYSE
Length:458
Mass (Da):49,251
Last modified:April 5, 2011 - v1
Checksum:iFE13A2719A3B91F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018891 Genomic DNA. No translation available.
AC080075 Genomic DNA. No translation available.
RefSeqiXP_005246282.1. XM_005246225.1.
UniGeneiHs.471156.

Genome annotation databases

EnsembliENST00000430418; ENSP00000408898; ENSG00000138443.
GeneIDi10152.
UCSCiuc061rpv.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018891 Genomic DNA. No translation available.
AC080075 Genomic DNA. No translation available.
RefSeqiXP_005246282.1. XM_005246225.1.
UniGeneiHs.471156.

3D structure databases

ProteinModelPortaliE9PEZ7.
SMRiE9PEZ7. Positions 1-155, 389-453.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000261017.

Proteomic databases

EPDiE9PEZ7.
PaxDbiE9PEZ7.
PRIDEiE9PEZ7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000430418; ENSP00000408898; ENSG00000138443.
GeneIDi10152.
UCSCiuc061rpv.1. human.

Organism-specific databases

CTDi10152.
HGNCiHGNC:24011. ABI2.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2546. Eukaryota.
ENOG410Y0MH. LUCA.
GeneTreeiENSGT00390000003756.

Miscellaneous databases

ChiTaRSiABI2. human.
GenomeRNAii10152.

Gene expression databases

BgeeiE9PEZ7.
ExpressionAtlasiE9PEZ7. baseline and differential.

Family and domain databases

InterProiIPR028457. ABI.
IPR028454. Abi2.
IPR012849. Abl-interactor_HHR_dom.
IPR001452. SH3_domain.
IPR000727. T_SNARE_dom.
[Graphical view]
PANTHERiPTHR10460. PTHR10460. 2 hits.
PTHR10460:SF3. PTHR10460:SF3. 2 hits.
PfamiPF07815. Abi_HHR. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
  4. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiE9PEZ7_HUMAN
AccessioniPrimary (citable) accession number: E9PEZ7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 8, 2016
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.