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Protein
Submitted name:

WD repeat-containing protein 6

Gene

WDR6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

SignaLinkiE9PDU5

Names & Taxonomyi

Protein namesi
Submitted name:
WD repeat-containing protein 6Imported
Gene namesi
Name:WDR6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000178252.17
HGNCiHGNC:12758 WDR6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000178252

PTM / Processingi

Proteomic databases

MaxQBiE9PDU5
PeptideAtlasiE9PDU5
PRIDEiE9PDU5

Expressioni

Gene expression databases

BgeeiENSG00000178252
ExpressionAtlasiE9PDU5 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiE9PDU5, 1 interactor
MINTiE9PDU5

Structurei

3D structure databases

ProteinModelPortaliE9PDU5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini154 – 284WD_REPEATS_REGIONInterPro annotationAdd BLAST131
Repeati154 – 187WDPROSITE-ProRule annotationAdd BLAST34

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0974 Eukaryota
ENOG410ZJ6J LUCA
GeneTreeiENSGT00420000029923

Family and domain databases

Gene3Di2.130.10.10, 4 hits
InterProiView protein in InterPro
IPR011044 Quino_amine_DH_bsu
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00400 WD40, 2 hits
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50969 SSF50969, 2 hits
SSF50978 SSF50978, 4 hits
PROSITEiView protein in PROSITE
PS50082 WD_REPEATS_2, 1 hit
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

E9PDU5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKRVQNLLG HYLIHGFRVR PEPNGDLDLE AMVAVFGSKG LRVVKISWGQ
60 70 80 90 100
GHFWELWRSG LWNMSDWIWD ARWLEGNIAL ALGHNSVVLY DPVVGCILQE
110 120 130 140 150
VPCTDRCTLS SACLIGDAWK ELTIVAGAVS NQLLVWYPAT ALADNKPVAP
160 170 180 190 200
DRRISGHVGI IFSMSYLESK GLLATASEDR SVRIWKVGDL RVPGGRVQNI
210 220 230 240 250
GHCFGHSARV WQVKLLENYL ISAGEDCVCL VWSHEGEILQ AFRGHQGRGI
260 270 280 290 300
RAIAAHERQA WVITGGDDSG IRLWHLVGRG YRGLGVSALC FKSRSRPGTL
310 320 330 340 350
KAVTLAGSWR LLAVTDTGAL YLYDVEVKCW EQLLEDKHFQ SYCLLEAAPG
360 370 380 390 400
PEGFGLCAMA NGEGRVKVVP INTPTAAVDQ TLFPGKVHSL SWALRGYEEL
410 420 430 440 450
LLLASGPGGV VACLEISAAP SGKAIFVKER CRYLLPPSKQ RWHTCSAFLP
460 470 480 490 500
PGDFLVCGDR RGSVLLFPSR PGLLKDPGVG GKARAGAGAP VVGSGSSGGG
510 520 530 540 550
NAFTGLGPVS TLPSLHGKQG VTSVTCHGGY VYTTGRDGAY YQLFVRDGQL
560 570 580 590 600
QPVLRQKSCR GMNWLAGLRI VPDGSMVILG FHANEFVVWN PRSHEKLHIV
610 620 630 640 650
NCGGGHRSWA FSDTEAAMAF AYLKDGDVML YRALGGCTRP HVILREGLHG
660 670 680 690 700
REITCVKRVG TITLGPEYGV PSFMQPDDLE PGSEGPDLTD IVITCSEDTT
710 720 730 740 750
VCVLALPTTT GSAHALTAVC NHISSVRAVA VWGIGTPGGP QDPQPGLTAH
760 770 780 790 800
VVSAGGRAEM HCFSIMVTPD PSTPSRLACH VMHLSSHRLD EYWDRQRNRH
810 820 830 840 850
RMVKVDPETR YMSLAVCELD QPGLGPLVAA ACSDGAVRLF LLQDSGRILQ
860 870 880 890 900
LLAETFHHKR CVLKVHSFTH EAPNQRRRLL LCSAATDGSL AFWDLTTMLD
910 920 930 940 950
HDSTVLEPPV DPGLPYRLGT PSLTLQAHSC GINSLHTLPT REGHHLVASG
960 970 980 990 1000
SEDGSLHVFV LAVEMLQLEE AVGEAGLVPQ LRVLEEYSVP CAHAAHVTGL
1010 1020 1030 1040 1050
KILSPSIMVS ASIDQRLTFW RLGHGEPTFM NSTVFHVPDV ADMDCWPVSP
1060 1070
EFGHRCALGG QGLEVYNWYD
Length:1,070
Mass (Da):116,169
Last modified:April 5, 2011 - v1
Checksum:iFD68E7D9589F3D01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC137630 Genomic DNA No translation available.
RefSeqiNP_001307476.1, NM_001320547.1
UniGeneiHs.654815

Genome annotation databases

EnsembliENST00000448293; ENSP00000413432; ENSG00000178252
GeneIDi11180
UCSCiuc011bbz.2 human

Similar proteinsi

Entry informationi

Entry nameiE9PDU5_HUMAN
AccessioniPrimary (citable) accession number: E9PDU5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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