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E9PDQ5 (E9PDQ5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:ARHGEF7 Ensembl ENSP00000417596
OrganismHomo sapiens (Human) [Reference proteome] Ensembl ENSP00000417596
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length547 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PH domain. RuleBase RU003350

Contains DH (DBL-homology) domain. SAAS SAAS001331

Contains PH domain. SAAS SAAS000219

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000417596

Sequences

Sequence LengthMass (Da)Tools
E9PDQ5 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 0F7899CC13022419

FASTA54761,630
        10         20         30         40         50         60 
MGSCSSQSVQ KTRRGRKVVL QNILETENEY SKELQTVLST YLRPLQTSEK LSSANISYLM 

        70         80         90        100        110        120 
GNLEEICSFQ QMLVQSLEEC TKLPEAQQRV GGCFLNLMPQ MKTLYLTYCA NHPSAVNVLT 

       130        140        150        160        170        180 
EHSEELGEFM ETKGASSPGI LVLTTGLSKP FMRLDKYPTL LKELERHMED YHTDRQDIQK 

       190        200        210        220        230        240 
SMAAFKNLSA QCQEVRKRKE LELQILTEAI RNWEGDDIKT LGNVTYMSQV LIQCAGSEEK 

       250        260        270        280        290        300 
NERYLLLFPN VLLMLSASPR MSGFIYQGKL PTTGMTITKL EDSENHRNAF EISGSMIERI 

       310        320        330        340        350        360 
LVSCNNQQDL QEWVEHLQKQ TKVTSVGNPT IKPHSVPSHT LPSHPVTPSS KHADSKPAPL 

       370        380        390        400        410        420 
TPAYHTLPHP SHHGTPHTTI NWGPLEPPKT PKPWSLSCLR PAPPLRPSAA LCYKEDLSKS 

       430        440        450        460        470        480 
PKTMKKLLPK RKPERKPSDE EFASRKSTAA LEEDAQILKV IEAYCTSAKT RQTLNSTWQG 

       490        500        510        520        530        540 
TDLMHNHVLA DDDQPSLDSL GRRSSLSRLE PSDLSEDSDY DSIWTAHSYR MGSTSRKSCC 


SYISHQN 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence and analysis of human chromosome 13."
Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T. expand/collapse author list , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.
Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL139086 Genomic DNA. No translation available.
AL353704 Genomic DNA. No translation available.
AL390754 Genomic DNA. No translation available.
UniGeneHs.508738.

3D structure databases

ProteinModelPortalE9PDQ5.
SMRE9PDQ5. Positions 16-322, 447-513.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEE9PDQ5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000478679; ENSP00000417596; ENSG00000102606.
KEGGhsa:8874.
UCSCuc010tjp.1. human.

Organism-specific databases

CTD8874.
HGNCHGNC:15607. ARHGEF7.
GenAtlasSearch...

Phylogenomic databases

KOK13710.

Gene expression databases

ArrayExpressE9PDQ5.
BgeeE9PDQ5.

Family and domain databases

Gene3D1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProIPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR011993. PH_like_dom.
IPR001849. Pleckstrin_homology.
[Graphical view]
PfamPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTSM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMSSF48065. SSF48065. 1 hit.
PROSITEPS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSARHGEF7. human.
GenomeRNAi8874.
NextBio35501671.

Entry information

Entry nameE9PDQ5_HUMAN
AccessionPrimary (citable) accession number: E9PDQ5
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 16, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.