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Protein
Submitted name:

Dipeptidyl aminopeptidase-like protein 6

Gene

DPP6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Protein family/group databases

ESTHERihuman-DPP6. DPP4N_Peptidase_S9.

Names & Taxonomyi

Protein namesi
Submitted name:
Dipeptidyl aminopeptidase-like protein 6Imported
Gene namesi
Name:DPP6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:3010. DPP6.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE9PDL2.
ExpressionAtlasiE9PDL2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PDL2.
SMRiE9PDL2. Positions 65-742.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119233.

Family and domain databases

Gene3Di2.140.10.30. 2 hits.
3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view]
PfamiPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PDL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTAKEPSAS GKSVQQQEQE LVGSNPPQRN WKGIAIALLV ILVICSLIVT
60 70 80 90 100
SVILLTPAED NSLSQKKKVT VEDLFSEDFK IHDPEAKWIS DTEFIYREQK
110 120 130 140 150
GTVRLWNVET NTSTVLIEGK KIESLRAIRY EISPDREYAL FSYNVEPIFI
160 170 180 190 200
FENNIYYCAH VGKQAIRVVS TGKEGVIYNG LSDWLYEEEI LKTHIAHWWS
210 220 230 240 250
PDGTRLAYAA INDSRVPIME LPTYTGSIYP TVKPYHYPKA GSENPSISLH
260 270 280 290 300
VIGLNGPTHD LEMMPPDDPR MREYYITMVK WATSTKVAVT WLNRAQNVSI
310 320 330 340 350
LTLCDATTGV CTKKHEDESE AWLHRQNEEP VFSKDGRKFF FIRAIPQGGR
360 370 380 390 400
GKFYHITVSS SQPNSSNDNI QSITSGDWDV TKILAYDEKG NKIYFLSTED
410 420 430 440 450
LPRRRQLYSA NTVGNFNRQC LSCDLVENCT YFSASFSHSM DFFLLKCEGP
460 470 480 490 500
GVPMVTVHNT TDKKKMFDLE TNEHVKKAIN DRQMPKVEYR DIEIDDYNLP
510 520 530 540 550
MQILKPATFT DTTHYPLLLV VDGTPGSQSV AEKFEVSWET VMVSSHGAVV
560 570 580 590 600
VKCDGRGSGF QGTKLLHEVR RRLGLLEEKD QMEAVRTMLK EQYIDRTRVA
610 620 630 640 650
VFGKDYGGYL STYILPAKGE NQGQTFTCGS ALSPITDFKL YASAFSERYL
660 670 680 690 700
GLHGLDNRAY EMTKVAHRVS ALEEQQFLII HPTADEKIHF QHTAELITQL
710 720 730 740 750
IRGKANYSLQ IYPDESHYFT SSSLKQHLYR SIINFFVECF RIQDKLLTVT

AKEDEEED
Length:758
Mass (Da):86,327
Last modified:April 5, 2011 - v1
Checksum:i0FCA84860AD946EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005588 Genomic DNA. No translation available.
AC006019 Genomic DNA. No translation available.
AC007129 Genomic DNA. No translation available.
AC024239 Genomic DNA. No translation available.
AC024730 Genomic DNA. No translation available.
AC073336 Genomic DNA. No translation available.
AC099341 Genomic DNA. No translation available.
AC104594 Genomic DNA. No translation available.
AC142230 Genomic DNA. No translation available.
AEKP01160869 Genomic DNA. No translation available.
RefSeqiNP_001277181.1. NM_001290252.1.
UniGeneiHs.490684.
Hs.551097.
Hs.669076.
Hs.703229.

Genome annotation databases

EnsembliENST00000427557; ENSP00000397303; ENSG00000130226.
GeneIDi1804.
UCSCiuc011kvq.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005588 Genomic DNA. No translation available.
AC006019 Genomic DNA. No translation available.
AC007129 Genomic DNA. No translation available.
AC024239 Genomic DNA. No translation available.
AC024730 Genomic DNA. No translation available.
AC073336 Genomic DNA. No translation available.
AC099341 Genomic DNA. No translation available.
AC104594 Genomic DNA. No translation available.
AC142230 Genomic DNA. No translation available.
AEKP01160869 Genomic DNA. No translation available.
RefSeqiNP_001277181.1. NM_001290252.1.
UniGeneiHs.490684.
Hs.551097.
Hs.669076.
Hs.703229.

3D structure databases

ProteinModelPortaliE9PDL2.
SMRiE9PDL2. Positions 65-742.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

ESTHERihuman-DPP6. DPP4N_Peptidase_S9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000427557; ENSP00000397303; ENSG00000130226.
GeneIDi1804.
UCSCiuc011kvq.2. human.

Organism-specific databases

CTDi1804.
HGNCiHGNC:3010. DPP6.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000119233.

Miscellaneous databases

ChiTaRSiDPP6. human.
GenomeRNAii1804.
NextBioi35501656.

Gene expression databases

BgeeiE9PDL2.
ExpressionAtlasiE9PDL2. baseline and differential.

Family and domain databases

Gene3Di2.140.10.30. 2 hits.
3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view]
PfamiPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PDL2_HUMAN
AccessioniPrimary (citable) accession number: E9PDL2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 22, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.