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Protein

Adenylyl cyclase-associated protein

Gene

CAP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Adenylyl cyclase-associated proteinUniRule annotation
Gene namesi
Name:CAP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000112186.11
HGNCiHGNC:20039 CAP2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000112186

PTM / Processingi

Proteomic databases

MaxQBiE9PDI2
PeptideAtlasiE9PDI2
PRIDEiE9PDI2

Expressioni

Gene expression databases

BgeeiENSG00000112186
ExpressionAtlasiE9PDI2 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliE9PDI2
SMRiE9PDI2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini291 – 429C-CAP/cofactor C-likeInterPro annotationAdd BLAST139

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 24Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the CAP family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000017955

Family and domain databases

Gene3Di1.25.40.330, 1 hit
2.160.20.70, 1 hit
InterProiView protein in InterPro
IPR001837 Adenylate_cyclase-assoc_CAP
IPR013912 Adenylate_cyclase-assoc_CAP_C
IPR013992 Adenylate_cyclase-assoc_CAP_N
IPR017901 C-CAP_CF_C-like
IPR016098 CAP/MinC_C
IPR028418 CAP2
IPR036223 CAP_C_sf
IPR028417 CAP_CS_C
IPR018106 CAP_CS_N
IPR036222 CAP_N_sf
IPR006599 CARP_motif
PANTHERiPTHR10652 PTHR10652, 2 hits
PTHR10652:SF2 PTHR10652:SF2, 2 hits
PfamiView protein in Pfam
PF08603 CAP_C, 1 hit
PF01213 CAP_N, 2 hits
SMARTiView protein in SMART
SM00673 CARP, 2 hits
SUPFAMiSSF101278 SSF101278, 1 hit
SSF69340 SSF69340, 1 hit
PROSITEiView protein in PROSITE
PS51329 C_CAP_COFACTOR_C, 1 hit
PS01088 CAP_1, 1 hit
PS01089 CAP_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9PDI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANMQGLVER LERAVSRLES LSAESHRPPG NCGEVNGVIA GVAPSVEAFD
60 70 80 90 100
KLMDSMVAEF LKNSRILAGD VETHNDVAAL LKPISEKIQE IQTFRERNRG
110 120 130 140 150
SNMFNHLSAV SESIPALGWI AVSPKPGPYV KEMNDAATFY TNRVLKDYKH
160 170 180 190 200
SDLRHVDWVK SYLNIWSELQ AYIKEHHTTG LTWSKTGPVA STVSAFSVLS
210 220 230 240 250
SGPGLPPPPP PLPPPGPPPL FENEGKKEES SPSRSALFAQ LNQGEAITKG
260 270 280 290 300
LRHVTDDQKT YKNPSLRAQG GQTQSPTKSH TPSPTSPKSY PSQKHAPVLE
310 320 330 340 350
LEGKKWRVEY QEDRNDLVIS ETELKQVAYI FKCEKSTIQI KGKVNSIIID
360 370 380 390 400
NCKKLGLVFD NVVGIVEVIN SQDIQIQVMG RVPTISINKT EGCHIYLSED
410 420 430 440 450
ALDCEIVSAK SSEMNILIPQ DGDYREFPIP EQFKTAWDGS KLITEPAEIM

A
Length:451
Mass (Da):49,823
Last modified:April 5, 2011 - v1
Checksum:i8BB2A10B133F5B74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL034372 Genomic DNA No translation available.
AL138824 Genomic DNA No translation available.
RefSeqiXP_011512535.1, XM_011514233.2
UniGeneiHs.132902

Genome annotation databases

EnsembliENST00000378990; ENSP00000368275; ENSG00000112186
GeneIDi10486
UCSCiuc011dja.3 human

Similar proteinsi

Entry informationi

Entry nameiE9PDI2_HUMAN
AccessioniPrimary (citable) accession number: E9PDI2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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