E9PDF2 (E9PDF2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-oxoglutarate dehydrogenase, mitochondrial Ensembl ENSP00000388183

Gene names

Name:

OGDH Ensembl ENSP00000388183

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000388183

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1034 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000388183

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Cellular_component	mitochondrion Inferred from direct assay. Source: HPA
Molecular_function	oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: InterPro thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9PDF2 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 2AC4BD2DE7077487	FASTA	1,034	117,244
	10 20 30 40 50 60 MFHLRTCAAK LRPLTASQTV KTFSQNRPAA ARTFQQIRCY SAPVAAEPFL SGTSSNYVEE 70 80 90 100 110 120 MYCAWLENPK SVHKSWDIFF RNTNAGAPPG TAYQSPLPLS RGSLAAVAHA QSLVEAQPNV 130 140 150 160 170 180 DKLVEDHLAV QSLIRAYQVR GHHIAKLDPL GISCVNFDDA PVTVSSNVDL AVFKERLRML 190 200 210 220 230 240 TVGGFYGLDE SDLDKVFHLP TTTFIGGQES ALPLREIIRR LEMAYCQHIG VEFMFINDLE 250 260 270 280 290 300 QCQWIRQKFE TPGIMQFTNE EKRTLLARLV RSTRFEEFLQ RKWSSEKRFG LEGCEVLIPA 310 320 330 340 350 360 LKTIIDKSSE NGVDYVIMGM PHRGRLNVLA NVIRKELEQI FCQFDSKLEA ADEGSGDVKY 370 380 390 400 410 420 HLGMYHRRIN RVTDRNITLS LVANPSHLEA ADPVVMGKTK AEQFYCGDTE GKKVMSILLH 430 440 450 460 470 480 GDAAFAGQGI VYETFHLSDL PSYTTHGTVH VVVNNQIGFT TDPRMARSSP YPTDVARVVN 490 500 510 520 530 540 APIFHVNSDD PEAVMYVCKV AAEWRSTFHK DVVVDLVCYR RNGHNEMDEP MFTQPLMYKQ 550 560 570 580 590 600 IRKQKPVLQK YAELLVSQGV VNQPEYEEEI SKYDKICEEA FARSKDEKIL HIKHWLDSPW 610 620 630 640 650 660 PGFFTLDGQP RSMSCPSTGL TEDILTHIGN VASSVPVENF TIHGGLSRIL KTRGEMVKNR 670 680 690 700 710 720 TVDWALAEYM AFGSLLKEGI HIRLSGQDVE RGTFSHRHHV LHDQNVDKRT CIPMNHLWPN 730 740 750 760 770 780 QAPYTVCNSS LSEYGVLGFE LGFAMASPNA LVLWEAQFGD FHNTAQCIID QFICPGQAKW 790 800 810 820 830 840 VRQNGIVLLL PHGMEGMGPE HSSARPERFL QMCNDDPDVL PDLKEANFDI NQLYDCNWVV 850 860 870 880 890 900 VNCSTPGNFF HVLRRQILLP FRKPLIIFTP KSLLRHPEAR SSFDEMLPGT HFQRVIPEDG 910 920 930 940 950 960 PAAQNPENVK RLLFCTGKVY YDLTRERKAR DMVGQVAITR IEQLSPFPFD LLLKEVQKYP 970 980 990 1000 1010 1020 NAELAWCQEE HKNQGYYDYV KPRLRTTISR AKPVWYAGRD PAAAPATGNK KTHLTELQRL 1030 LDTAFDLDVF KNFS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence of human chromosome 7." Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K. Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC004859 Genomic DNA. No translation available. AC011894 Genomic DNA. No translation available.
IPI	IPI00829595.
3D structure databases
ProteinModelPortal	E9PDF2.
SMR	E9PDF2. Positions 130-1025.
ModBase	Search...
Proteomic databases
PRIDE	E9PDF2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000447398; ENSP00000388183; ENSG00000105953.
UCSC	uc003tlp.3. human.
Organism-specific databases
HGNC	HGNC:8124. OGDH.
GenAtlas	Search...
Gene expression databases
ArrayExpress	E9PDF2.
Bgee	E9PDF2.
Family and domain databases
InterPro	IPR011603. 2oxoglutarate_DH_E1. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
PANTHER	PTHR23152. PTHR23152. 1 hit.
Pfam	PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	OGDH. human.
NextBio	35501634.

Entry information

Entry name

E9PDF2_HUMAN

Accession

Primary (citable) accession number: E9PDF2

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.