ID   E9PDC4_HUMAN            Unreviewed;       121 AA.
AC   E9PDC4;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 2.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=Meis homeobox 1 {ECO:0000313|Ensembl:ENSP00000397418.2};
DE   Flags: Fragment;
GN   Name=MEIS1 {ECO:0000313|Ensembl:ENSP00000397418.2};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000397418.2, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000397418.2, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA   Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA   Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA   Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA   Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA   Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA   Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA   Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA   Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA   Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA   Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA   Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA   Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA   Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA   Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA   Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT   4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0007829|PubMed:17081983}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=17081983; DOI=10.1016/j.cell.2006.09.026;
RA   Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.;
RT   "Global, in vivo, and site-specific phosphorylation dynamics in signaling
RT   networks.";
RL   Cell 127:635-648(2006).
RN   [3] {ECO:0007829|PubMed:23186163}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=23186163;
RA   Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA   Mohammed S.;
RT   "Toward a comprehensive characterization of a human cancer cell
RT   phosphoproteome.";
RL   J. Proteome Res. 12:260-271(2013).
RN   [4] {ECO:0000313|Ensembl:ENSP00000397418.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC007392; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC092669; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC093641; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   MassIVE; E9PDC4; -.
DR   MaxQB; E9PDC4; -.
DR   PeptideAtlas; E9PDC4; -.
DR   ProteomicsDB; 19631; -.
DR   Antibodypedia; 3157; 395 antibodies from 41 providers.
DR   Ensembl; ENST00000437869.1; ENSP00000397418.2; ENSG00000143995.20.
DR   UCSC; uc061jwk.1; human.
DR   HGNC; HGNC:7000; MEIS1.
DR   VEuPathDB; HostDB:ENSG00000143995; -.
DR   GeneTree; ENSGT00940000156327; -.
DR   HOGENOM; CLU_144365_0_0_1; -.
DR   ChiTaRS; MEIS1; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000143995; Expressed in right uterine tube and 182 other cell types or tissues.
DR   ExpressionAtlas; E9PDC4; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   InterPro; IPR032453; PKNOX/Meis_N.
DR   Pfam; PF16493; Meis_PKNOX_N; 1.
PE   1: Evidence at protein level;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Proteomics identification {ECO:0007829|MaxQB:E9PDC4,
KW   ECO:0007829|PeptideAtlas:E9PDC4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN          19..65
FT                   /note="MEIS N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16493"
FT   REGION          61..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        97..121
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000397418.2"
FT   NON_TER         121
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000397418.2"
SQ   SEQUENCE   121 AA;  13397 MW;  DABB0D7A87C51BA8 CRC64;
     XLCFESPEIS RPVFPCLQMI QAIQVLRFHL LELEKVHELC DNFCHRYISC LKGKMPIDLV
     IDDREGGSKS DSEDITRSAN LTDQPSWNRD HDDTASTRSG GTPGPSSGGH TSHSGDNSSE
     Q
//