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Protein
Submitted name:

Sphingosine kinase 2, isoform CRA_e

Gene

SPHK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Sphingosine kinase 2, isoform CRA_eImported
Gene namesi
Name:SPHK2Imported
ORF Names:hCG_15274Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000063176.15
HGNCiHGNC:18859 SPHK2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000063176

PTM / Processingi

Proteomic databases

PeptideAtlasiE9PCV4
PRIDEiE9PCV4

Expressioni

Gene expression databases

BgeeiENSG00000063176
ExpressionAtlasiE9PCV4 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 119DAGKcInterPro annotationAdd BLAST119

Phylogenomic databases

eggNOGiKOG1116 Eukaryota
COG1597 LUCA
GeneTreeiENSGT00690000101761

Family and domain databases

Gene3Di3.40.50.10330, 1 hit
InterProiView protein in InterPro
IPR017438 ATP-NAD_kinase_N
IPR001206 Diacylglycerol_kinase_cat_dom
IPR016064 NAD/diacylglycerol_kinase_sf
PfamiView protein in Pfam
PF00781 DAGK_cat, 1 hit
SUPFAMiSSF111331 SSF111331, 2 hits
PROSITEiView protein in PROSITE
PS50146 DAGK, 1 hit

Sequencei

Sequence statusi: Complete.

E9PCV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISEAGLSFN LIQTERQNHA RELVQGLSLS EWDGIVTVSG DGLLHEVLNG
60 70 80 90 100
LLDRPDWEEA VKMPVGILPC GSGNALAGAV NQHGGFEPAL GLDLLLNCSL
110 120 130 140 150
LLCRGGGHPL DLLSVTLASG SRCFSFLSVA WGFVSDVDIQ SERFRALGSA
160 170 180 190 200
RFTLGTVLGL ATLHTYRGRL SYLPATVEPA SPTPAHSLPR AKSELTLTPD
210 220 230 240 250
PAPPMAHSPL HRSVSDLPLP LPQPALASPG SPEPLPILSL NGGGPELAGD
260 270 280 290 300
WGGAGDAPLS PDPLLSSPPG SPKAALHSPV SEGAPVIPPS SGLPLPTPDA
310 320 330 340 350
RVGASTCGPP DHLLPPLGTP LPPDWVTLEG DFVLMLAISP SHLGADLVAA
360 370 380 390 400
PHARFDDGLV HLCWVRSGIS RAALLRLFLA MERGSHFSLG CPQLGYAAAR
410 420 430 440
AFRLEPLTPR GVLTVDGEQV EYGPLQAQMH PGIGTLLTGP PGCPGREP
Length:448
Mass (Da):46,563
Last modified:October 29, 2014 - v2
Checksum:i9823B293362626FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022154 Genomic DNA No translation available.
CH471177 Genomic DNA Translation: EAW52371.1
RefSeqiNP_001230805.1, NM_001243876.1
XP_016882498.1, XM_017027009.1
UniGeneiHs.528006

Genome annotation databases

EnsembliENST00000340932; ENSP00000341091; ENSG00000063176
GeneIDi56848
UCSCiuc002pjt.3 human

Similar proteinsi

Entry informationi

Entry nameiE9PCV4_HUMAN
AccessioniPrimary (citable) accession number: E9PCV4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 29, 2014
Last modified: June 20, 2018
This is version 53 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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