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Protein
Submitted name:

Ankyrin-2

Gene

ANK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ankyrin-2Imported
Gene namesi
Name:ANK2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:493. ANK2.

PTM / Processingi

Proteomic databases

PeptideAtlasiE9PCH6.

Expressioni

Gene expression databases

BgeeiENSG00000145362.
ExpressionAtlasiE9PCH6. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PCH6.
SMRiE9PCH6. Positions 175-738.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini175 – 282108ZU5InterPro annotationAdd
BLAST
Domaini660 – 74485DeathInterPro annotationAdd
BLAST

Phylogenomic databases

GeneTreeiENSGT00840000129677.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR030301. Ankyrin-B.
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR000906. ZU5_dom.
[Graphical view]
PANTHERiPTHR24123:SF17. PTHR24123:SF17. 2 hits.
PfamiPF00531. Death. 1 hit.
PF00791. ZU5. 2 hits.
[Graphical view]
SMARTiSM00005. DEATH. 1 hit.
SM00218. ZU5. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS51145. ZU5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PCH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGNTALAIA KRLGYISVVD TLKVVTEEVT TTTTTITEKH KLNVPETMTE
60 70 80 90 100
VLDVSDEEGD DTMTGDGGEY LRPEDLKELG DDSLPSSQFL DGMNYLRYSL
110 120 130 140 150
EGGRSDSLRS FSSDRSHTLS HASYLRDSAV MDDSVVIPSH QVSTLAKEAE
160 170 180 190 200
RNSYRLSWGT ENLDNVALSS SPIHSGFLVS FMVDARGGAM RGCRHNGLRI
210 220 230 240 250
IIPPRKCTAP TRVTCRLVKR HRLATMPPMV EGEGLASRLI EVGPSGAQFL
260 270 280 290 300
GPVIVEIPHF AALRGKEREL VVLRSENGDS WKEHFCDYTE DELNEILNGM
310 320 330 340 350
DEVLDSPEDL EKKRICRIIT RDFPQYFAVV SRIKQDSNLI GPEGGVLSST
360 370 380 390 400
VVPQVQAVFP EGALTKRIRV GLQAQPMHSE LVKKILGNKA TFSPIVTLEP
410 420 430 440 450
RRRKFHKPIT MTIPVPKASS DVMLNGFGGD APTLRLLCSI TGGTTPAQWE
460 470 480 490 500
DITGTTPLTF VNECVSFTTN VSARFWLIDC RQIQESVTFA SQVYREIICV
510 520 530 540 550
PYMAKFVVFA KSHDPIEARL RCFCMTDDKV DKTLEQQENF AEVARSRDVE
560 570 580 590 600
VLEGKPIYVD CFGNLVPLTK SGQHHIFSFF AFKENRLPLF VKVRDTTQEP
610 620 630 640 650
CGRLSFMKEP KSTRGLVHQA ICNLNITLPI YTKESESDQE QEEEIDMTSE
660 670 680 690 700
KNPQDEQERI EERLAYIADH LGFSWTELAR ELDFTEEQIH QIRIENPNSL
710 720 730 740 750
QDQSHALLKY WLERDGKHAT DTNLVECLTK INRMDIVHLM ETNTEPLQER
760 770 780 790 800
ISHSYAEIEQ TITLDHSEGF SVLQEELCTA QHKQKEEQAV SKESETCDHP
810 820 830 840 850
PIVSEEDISV GYSTFQDGVP KTEGDSSATA LFPQTHKEQV QQDFSGKMQD
860 870 880 890 900
LPEESSLEYQ QEYFVTTPGT ETSETQKAMI VPSSPSKTPE EVSTPAEEEK
910 920 930 940 950
LYLQTPTSSE RGGSPIIQEP EEPSEHREES SPRKTSLVIV ESADNQPETC
960 970 980 990 1000
ERLDEDAAFE KGDDMPEIPP ETVTEEEYID EHGHTVVKKV TRKIIRRYVS
1010 1020 1030 1040
SEGTEKEEIM VQGMPQEPVN IEEGDGYSKV IKRVVLKSDT EQSEDNNE
Length:1,048
Mass (Da):117,845
Last modified:April 5, 2011 - v1
Checksum:i6878B3FDC25CE6F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004057 Genomic DNA. No translation available.
AC017007 Genomic DNA. No translation available.
AC093617 Genomic DNA. No translation available.
AC093879 Genomic DNA. No translation available.
AC093900 Genomic DNA. No translation available.
AC108042 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000509550; ENSP00000426944; ENSG00000145362.
UCSCiuc011cgc.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004057 Genomic DNA. No translation available.
AC017007 Genomic DNA. No translation available.
AC093617 Genomic DNA. No translation available.
AC093879 Genomic DNA. No translation available.
AC093900 Genomic DNA. No translation available.
AC108042 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9PCH6.
SMRiE9PCH6. Positions 175-738.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiE9PCH6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000509550; ENSP00000426944; ENSG00000145362.
UCSCiuc011cgc.3. human.

Organism-specific databases

HGNCiHGNC:493. ANK2.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00840000129677.

Miscellaneous databases

ChiTaRSiANK2. human.

Gene expression databases

BgeeiENSG00000145362.
ExpressionAtlasiE9PCH6. baseline and differential.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR030301. Ankyrin-B.
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR000906. ZU5_dom.
[Graphical view]
PANTHERiPTHR24123:SF17. PTHR24123:SF17. 2 hits.
PfamiPF00531. Death. 1 hit.
PF00791. ZU5. 2 hits.
[Graphical view]
SMARTiSM00005. DEATH. 1 hit.
SM00218. ZU5. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS51145. ZU5. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9PCH6_HUMAN
AccessioniPrimary (citable) accession number: E9PCH6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 7, 2016
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.