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Protein
Submitted name:

Nuclear receptor subfamily 1 group I member 3

Gene

NR1I3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi7 – 54Nuclear receptorPROSITE-ProRule annotationAdd BLAST48

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 1 group I member 3Imported
Gene namesi
Name:NR1I3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000143257.11.
HGNCiHGNC:7969. NR1I3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143257.

PTM / Processingi

Proteomic databases

PRIDEiE9PCF2.

Expressioni

Gene expression databases

BgeeiENSG00000143257.
ExpressionAtlasiE9PCF2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PCF2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 54Nuclear receptorInterPro annotationAdd BLAST48

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00870000136372.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR035500. NHR_like_dom_sf.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001728. ThyrH_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR00398. STRDHORMONER.
PR00546. THYROIDHORMR.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PCF2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPKRSRRTV SKSIGPTCPF AGSCEVSKTQ RRHCPACRLQ KCLDAGMRKD
60 70 80 90 100
MILSAEALAL RRAKQAQRRA QQTPVQLSKE QEELIRTLLG AHTRHMGTMF
110 120 130 140 150
EQFVQFRPPA HLFIHHQPLP TLAPVLPLVT HFADINTFMV LQVIKFTKDL
160 170 180 190 200
PVFRSLPIED QISLLKGAAV EICHIVLNTT FCLQTQNFLC GPLRYTIEDG
210 220 230 240 250
ARVGFQVEFL ELLFHFHGTL RKLQLQEPEY VLLAAMALFS PDRPGVTQRD
260 270 280 290
EIDQLQEEMA LTLQSYIKGQ QRRPRDRYGG TLRAWRPHQG RKGLVKH
Length:297
Mass (Da):33,993
Last modified:April 5, 2011 - v1
Checksum:iA82EF34D311A3127
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590714 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000506209; ENSP00000423089; ENSG00000143257.
UCSCiuc010pkm.3. human.

Similar proteinsi

Entry informationi

Entry nameiE9PCF2_HUMAN
AccessioniPrimary (citable) accession number: E9PCF2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: January 31, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported