E9PC66 (E9PC66_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Zinc finger protein with KRAB and SCAN domains 1 Ensembl ENSP00000409172

Gene names

Name:

ZKSCAN1 Ensembl ENSP00000409172

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000409172

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	527 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 1 SCAN box domain. SAAS SAAS008916
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000409172

Ontologies

Keywords
Biological process	Transcription Transcription regulation SAAS SAAS008916
Cellular component	Nucleus SAAS SAAS003309
Domain	Repeat SAAS SAAS001909 Zinc-finger SAAS SAAS001909
Ligand	Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW viral reproduction Inferred from electronic annotation. Source: InterPro
Cellular_component	mitochondrion Inferred from direct assay. Source: HPA nucleus Inferred from direct assay. Source: HPA
Molecular_function	nucleic acid binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9PC66 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: CECD5F79DF559846	FASTA	527	59,675
	10 20 30 40 50 60 MWGQDSTLQD TPPPDPEIFR QRFRRFCYQN TFGPREALSR LKELCHQWLR PEINTKEQIL 70 80 90 100 110 120 ELLVLEQFLS ILPKELQVWL QEYRPDSGEE AVTLLEDLEL DLSGQQVPGQ VHGPEMLARG 130 140 150 160 170 180 MVPLDPVQES SSFDLHHEAT QSHFKHSSRK PRLLQSRALP AAHIPAPPHE GSPRDQAMAS 190 200 210 220 230 240 ALFTADSQAM VKIEDMAVSL ILEEWGCQNL ARRNLSRDNR QENYGSAFPQ GGENRNENEE 250 260 270 280 290 300 STSKAETSED SASRGETTGR SQKEFGEKRD QEGKTGERQQ KNPEEKTRKE KRDSGPAIGK 310 320 330 340 350 360 DKKTITGERG PREKGKGLGR SFSLSSNFTT PEEVPTGTKS HRCDECGKCF TRSSSLIRHK 370 380 390 400 410 420 IIHTGEKPYE CSECGKAFSL NSNLVLHQRI HTGEKPHECN ECGKAFSHSS NLILHQRIHS 430 440 450 460 470 480 GEKPYECNEC GKAFSQSSDL TKHQRIHTGE KPYECSECGK AFNRNSYLIL HRRIHTREKP 490 500 510 520 YKCTKCGKAF TRSSTLTLHH RIHARERASE YSPASLDAFG AFLKSCV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence of human chromosome 7." Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K. Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC004522 Genomic DNA. No translation available. AC093619 Genomic DNA. No translation available.
IPI	IPI00926645.
3D structure databases
ProteinModelPortal	E9PC66.
SMR	E9PC66. Positions 14-102, 306-508.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000426572; ENSP00000409172; ENSG00000106261.
Organism-specific databases
HGNC	HGNC:13101. ZKSCAN1.
GenAtlas	Search...
Gene expression databases
ArrayExpress	E9PC66.
Bgee	E9PC66.
Family and domain databases
Gene3D	3.30.160.60. 6 hits.
InterPro	IPR001909. Krueppel-associated_box. IPR008916. Retrov_capsid_C. IPR003309. Tscrpt_reg_SCAN. IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. IPR013087. Znf_C2H2/integrase_DNA-bd. [Graphical view]
Pfam	PF01352. KRAB. 1 hit. PF02023. SCAN. 1 hit. [Graphical view]
SMART	SM00349. KRAB. 1 hit. SM00431. SCAN. 1 hit. SM00355. ZnF_C2H2. 6 hits. [Graphical view]
SUPFAM	SSF109640. Krueppel-associated_box. 1 hit. SSF47353. Retrov_capsid_C. 1 hit.
PROSITE	PS50805. KRAB. 1 hit. PS50804. SCAN_BOX. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 6 hits. PS50157. ZINC_FINGER_C2H2_2. 6 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ZKSCAN1. human.
NextBio	35501500.

Entry information

Entry name

E9PC66_HUMAN

Accession

Primary (citable) accession number: E9PC66

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.