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E9PC66

- E9PC66_HUMAN

UniProt

E9PC66 - E9PC66_HUMAN

Protein
Submitted name:

Zinc finger protein with KRAB and SCAN domains 1

Gene

ZKSCAN1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulationSAAS annotation

    Keywords - Ligandi

    DNA-bindingSAAS annotation, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Zinc finger protein with KRAB and SCAN domains 1Imported
    Gene namesi
    Name:ZKSCAN1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 7

    Organism-specific databases

    HGNCiHGNC:13101. ZKSCAN1.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-KW

    Keywords - Cellular componenti

    NucleusSAAS annotation

    Expressioni

    Gene expression databases

    ArrayExpressiE9PC66.
    BgeeiE9PC66.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PC66.
    SMRiE9PC66. Positions 14-102, 306-508.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains SCAN box domain.SAAS annotation

    Keywords - Domaini

    RepeatSAAS annotation, Zinc-fingerSAAS annotation

    Phylogenomic databases

    KOiK09229.

    Family and domain databases

    Gene3Di3.30.160.60. 6 hits.
    InterProiIPR001909. Krueppel-associated_box.
    IPR008916. Retrov_capsid_C.
    IPR003309. Tscrpt_reg_SCAN.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    PfamiPF01352. KRAB. 1 hit.
    PF02023. SCAN. 1 hit.
    [Graphical view]
    SMARTiSM00349. KRAB. 1 hit.
    SM00431. SCAN. 1 hit.
    SM00355. ZnF_C2H2. 6 hits.
    [Graphical view]
    SUPFAMiSSF109640. SSF109640. 1 hit.
    SSF47353. SSF47353. 1 hit.
    PROSITEiPS50805. KRAB. 1 hit.
    PS50804. SCAN_BOX. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 6 hits.
    PS50157. ZINC_FINGER_C2H2_2. 6 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9PC66-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWGQDSTLQD TPPPDPEIFR QRFRRFCYQN TFGPREALSR LKELCHQWLR    50
    PEINTKEQIL ELLVLEQFLS ILPKELQVWL QEYRPDSGEE AVTLLEDLEL 100
    DLSGQQVPGQ VHGPEMLARG MVPLDPVQES SSFDLHHEAT QSHFKHSSRK 150
    PRLLQSRALP AAHIPAPPHE GSPRDQAMAS ALFTADSQAM VKIEDMAVSL 200
    ILEEWGCQNL ARRNLSRDNR QENYGSAFPQ GGENRNENEE STSKAETSED 250
    SASRGETTGR SQKEFGEKRD QEGKTGERQQ KNPEEKTRKE KRDSGPAIGK 300
    DKKTITGERG PREKGKGLGR SFSLSSNFTT PEEVPTGTKS HRCDECGKCF 350
    TRSSSLIRHK IIHTGEKPYE CSECGKAFSL NSNLVLHQRI HTGEKPHECN 400
    ECGKAFSHSS NLILHQRIHS GEKPYECNEC GKAFSQSSDL TKHQRIHTGE 450
    KPYECSECGK AFNRNSYLIL HRRIHTREKP YKCTKCGKAF TRSSTLTLHH 500
    RIHARERASE YSPASLDAFG AFLKSCV 527
    Length:527
    Mass (Da):59,675
    Last modified:April 5, 2011 - v1
    Checksum:iCECD5F79DF559846
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004522 Genomic DNA. No translation available.
    AC093619 Genomic DNA. No translation available.
    RefSeqiNP_001273983.1. NM_001287054.1.
    UniGeneiHs.615360.
    Hs.633338.
    Hs.743424.

    Genome annotation databases

    EnsembliENST00000426572; ENSP00000409172; ENSG00000106261.
    GeneIDi7586.
    KEGGihsa:7586.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004522 Genomic DNA. No translation available.
    AC093619 Genomic DNA. No translation available.
    RefSeqi NP_001273983.1. NM_001287054.1.
    UniGenei Hs.615360.
    Hs.633338.
    Hs.743424.

    3D structure databases

    ProteinModelPortali E9PC66.
    SMRi E9PC66. Positions 14-102, 306-508.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000426572 ; ENSP00000409172 ; ENSG00000106261 .
    GeneIDi 7586.
    KEGGi hsa:7586.

    Organism-specific databases

    CTDi 7586.
    HGNCi HGNC:13101. ZKSCAN1.
    GenAtlasi Search...

    Phylogenomic databases

    KOi K09229.

    Miscellaneous databases

    ChiTaRSi ZKSCAN1. human.
    GenomeRNAii 7586.
    NextBioi 35501500.

    Gene expression databases

    ArrayExpressi E9PC66.
    Bgeei E9PC66.

    Family and domain databases

    Gene3Di 3.30.160.60. 6 hits.
    InterProi IPR001909. Krueppel-associated_box.
    IPR008916. Retrov_capsid_C.
    IPR003309. Tscrpt_reg_SCAN.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    Pfami PF01352. KRAB. 1 hit.
    PF02023. SCAN. 1 hit.
    [Graphical view ]
    SMARTi SM00349. KRAB. 1 hit.
    SM00431. SCAN. 1 hit.
    SM00355. ZnF_C2H2. 6 hits.
    [Graphical view ]
    SUPFAMi SSF109640. SSF109640. 1 hit.
    SSF47353. SSF47353. 1 hit.
    PROSITEi PS50805. KRAB. 1 hit.
    PS50804. SCAN_BOX. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 6 hits.
    PS50157. ZINC_FINGER_C2H2_2. 6 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of human chromosome 7."
      Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
      , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
      Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE9PC66_HUMAN
    AccessioniPrimary (citable) accession number: E9PC66
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3