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E9PC66

- E9PC66_HUMAN

UniProt

E9PC66 - E9PC66_HUMAN

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Protein
Submitted name: Zinc finger protein with KRAB and SCAN domains 1
Gene
ZKSCAN1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotations

Keywords - Ligandi

DNA-bindingSAAS annotations, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein with KRAB and SCAN domains 1Imported
Gene namesi
Name:ZKSCAN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:13101. ZKSCAN1.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotations

Expressioni

Gene expression databases

ArrayExpressiE9PC66.
BgeeiE9PC66.

Structurei

3D structure databases

ProteinModelPortaliE9PC66.
SMRiE9PC66. Positions 14-102, 306-508.

Family & Domainsi

Sequence similaritiesi

Contains SCAN box domain.SAAS annotations

Keywords - Domaini

RepeatSAAS annotations, Zinc-fingerSAAS annotations

Phylogenomic databases

KOiK09229.

Family and domain databases

Gene3Di3.30.160.60. 6 hits.
InterProiIPR001909. Krueppel-associated_box.
IPR008916. Retrov_capsid_C.
IPR003309. Tscrpt_reg_SCAN.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF02023. SCAN. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 6 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
SSF47353. SSF47353. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PC66-1 [UniParc]FASTAAdd to Basket

« Hide

MWGQDSTLQD TPPPDPEIFR QRFRRFCYQN TFGPREALSR LKELCHQWLR    50
PEINTKEQIL ELLVLEQFLS ILPKELQVWL QEYRPDSGEE AVTLLEDLEL 100
DLSGQQVPGQ VHGPEMLARG MVPLDPVQES SSFDLHHEAT QSHFKHSSRK 150
PRLLQSRALP AAHIPAPPHE GSPRDQAMAS ALFTADSQAM VKIEDMAVSL 200
ILEEWGCQNL ARRNLSRDNR QENYGSAFPQ GGENRNENEE STSKAETSED 250
SASRGETTGR SQKEFGEKRD QEGKTGERQQ KNPEEKTRKE KRDSGPAIGK 300
DKKTITGERG PREKGKGLGR SFSLSSNFTT PEEVPTGTKS HRCDECGKCF 350
TRSSSLIRHK IIHTGEKPYE CSECGKAFSL NSNLVLHQRI HTGEKPHECN 400
ECGKAFSHSS NLILHQRIHS GEKPYECNEC GKAFSQSSDL TKHQRIHTGE 450
KPYECSECGK AFNRNSYLIL HRRIHTREKP YKCTKCGKAF TRSSTLTLHH 500
RIHARERASE YSPASLDAFG AFLKSCV 527
Length:527
Mass (Da):59,675
Last modified:April 5, 2011 - v1
Checksum:iCECD5F79DF559846
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC004522 Genomic DNA. No translation available.
AC093619 Genomic DNA. No translation available.
RefSeqiNP_001273983.1. NM_001287054.1.
UniGeneiHs.615360.
Hs.633338.
Hs.743424.

Genome annotation databases

EnsembliENST00000426572; ENSP00000409172; ENSG00000106261.
GeneIDi7586.
KEGGihsa:7586.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC004522 Genomic DNA. No translation available.
AC093619 Genomic DNA. No translation available.
RefSeqi NP_001273983.1. NM_001287054.1.
UniGenei Hs.615360.
Hs.633338.
Hs.743424.

3D structure databases

ProteinModelPortali E9PC66.
SMRi E9PC66. Positions 14-102, 306-508.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000426572 ; ENSP00000409172 ; ENSG00000106261 .
GeneIDi 7586.
KEGGi hsa:7586.

Organism-specific databases

CTDi 7586.
HGNCi HGNC:13101. ZKSCAN1.
GenAtlasi Search...

Phylogenomic databases

KOi K09229.

Miscellaneous databases

ChiTaRSi ZKSCAN1. human.
GenomeRNAii 7586.
NextBioi 35501500.

Gene expression databases

ArrayExpressi E9PC66.
Bgeei E9PC66.

Family and domain databases

Gene3Di 3.30.160.60. 6 hits.
InterProi IPR001909. Krueppel-associated_box.
IPR008916. Retrov_capsid_C.
IPR003309. Tscrpt_reg_SCAN.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
Pfami PF01352. KRAB. 1 hit.
PF02023. SCAN. 1 hit.
[Graphical view ]
SMARTi SM00349. KRAB. 1 hit.
SM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 6 hits.
[Graphical view ]
SUPFAMi SSF109640. SSF109640. 1 hit.
SSF47353. SSF47353. 1 hit.
PROSITEi PS50805. KRAB. 1 hit.
PS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PC66_HUMAN
AccessioniPrimary (citable) accession number: E9PC66
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 11, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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