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Protein
Submitted name:

CUGBP Elav-like family member 2

Gene

CELF2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

RNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
CUGBP Elav-like family member 2Imported
Gene namesi
Name:CELF2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:2550. CELF2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiE9PC62.
MaxQBiE9PC62.
PaxDbiE9PC62.
PRIDEiE9PC62.

Expressioni

Gene expression databases

BgeeiE9PC62.
ExpressionAtlasiE9PC62. baseline and differential.
GenevisibleiE9PC62. HS.

Interactioni

Protein-protein interaction databases

IntActiE9PC62. 1 interaction.
STRINGi9606.ENSP00000389951.

Structurei

3D structure databases

ProteinModelPortaliE9PC62.
SMRiE9PC62. Positions 43-218, 401-521.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini47 – 13084RRM (RNA recognition motif)InterPro annotationAdd
BLAST
Domaini139 – 21981RRM (RNA recognition motif)InterPro annotationAdd
BLAST
Domaini436 – 51479RRM (RNA recognition motif)InterPro annotationAdd
BLAST

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG0146. Eukaryota.
ENOG410XNTW. LUCA.
GeneTreeiENSGT00560000076837.
OMAiRTSELAF.
PhylomeDBiE9PC62.
TreeFamiTF314924.

Family and domain databases

Gene3Di3.30.70.330. 3 hits.
InterProiIPR002343. Hud_Sxl_RNA.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 3 hits.
[Graphical view]
PRINTSiPR00961. HUDSXLRNA.
SMARTiSM00360. RRM. 3 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 3 hits.
PROSITEiPS50102. RRM. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PC62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSAFKLDFL PDMMVEGRLL VPDRINGTAN KMNGALDHSD QPDPDAIKMF
60 70 80 90 100
VGQIPRSWSE KELKELFEPY GAVYQINVLR DRSQNPPQSK GCCFVTFYTR
110 120 130 140 150
KAALEAQNAL HNIKTLPGMH HPIQMKPADS EKSNAVEDRK LFIGMVSKKC
160 170 180 190 200
NENDIRVMFS PFGQIEECRI LRGPDGLSRG CAFVTFSTRA MAQNAIKAMH
210 220 230 240 250
QSQTMEGCSS PIVVKFADTQ KDKEQRRLQQ QLAQQMQQLN TATWGNLTGL
260 270 280 290 300
GGLTPQYLAL LQQATSSSNL GAFSGIQQMA GMNALQLQNL ATLAAAAAAA
310 320 330 340 350
QTSATSTNAN PLSTTSSALG ALTSPVAAST PNSTAGAAMN SLTSLGTLQG
360 370 380 390 400
LAGATVGLNN INALAVAQML SGMAALNGGL GATGLTNGTA GTMDALTQAY
410 420 430 440 450
SGIQQYAAAA LPTLYSQSLL QQQSAAGSQK EGPEGANLFI YHLPQEFGDQ
460 470 480 490 500
DILQMFMPFG NVISAKVFID KQTNLSKCFG FVSYDNPVSA QAAIQAMNGF
510 520
QIGMKRLKVQ LKRSKNDSKP Y
Length:521
Mass (Da):55,732
Last modified:April 5, 2011 - v1
Checksum:i512A0B025AE6E1BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC026887 Genomic DNA. No translation available.
AL136320 Genomic DNA. No translation available.
AL136369 Genomic DNA. No translation available.
AL138769 Genomic DNA. No translation available.
AL157704 Genomic DNA. No translation available.
AL162408 Genomic DNA. No translation available.
KF573678 Genomic DNA. No translation available.
RefSeqiNP_006552.3. NM_006561.3.
UniGeneiHs.309288.

Genome annotation databases

EnsembliENST00000542579; ENSP00000443926; ENSG00000048740.
ENST00000633077; ENSP00000488690; ENSG00000048740.
GeneIDi10659.
UCSCiuc031vxd.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC026887 Genomic DNA. No translation available.
AL136320 Genomic DNA. No translation available.
AL136369 Genomic DNA. No translation available.
AL138769 Genomic DNA. No translation available.
AL157704 Genomic DNA. No translation available.
AL162408 Genomic DNA. No translation available.
KF573678 Genomic DNA. No translation available.
RefSeqiNP_006552.3. NM_006561.3.
UniGeneiHs.309288.

3D structure databases

ProteinModelPortaliE9PC62.
SMRiE9PC62. Positions 43-218, 401-521.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiE9PC62. 1 interaction.
STRINGi9606.ENSP00000389951.

Proteomic databases

EPDiE9PC62.
MaxQBiE9PC62.
PaxDbiE9PC62.
PRIDEiE9PC62.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000542579; ENSP00000443926; ENSG00000048740.
ENST00000633077; ENSP00000488690; ENSG00000048740.
GeneIDi10659.
UCSCiuc031vxd.2. human.

Organism-specific databases

CTDi10659.
HGNCiHGNC:2550. CELF2.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0146. Eukaryota.
ENOG410XNTW. LUCA.
GeneTreeiENSGT00560000076837.
OMAiRTSELAF.
PhylomeDBiE9PC62.
TreeFamiTF314924.

Miscellaneous databases

ChiTaRSiCELF2. human.
GenomeRNAii10659.
NextBioi40529.

Gene expression databases

BgeeiE9PC62.
ExpressionAtlasiE9PC62. baseline and differential.
GenevisibleiE9PC62. HS.

Family and domain databases

Gene3Di3.30.70.330. 3 hits.
InterProiIPR002343. Hud_Sxl_RNA.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 3 hits.
[Graphical view]
PRINTSiPR00961. HUDSXLRNA.
SMARTiSM00360. RRM. 3 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 3 hits.
PROSITEiPS50102. RRM. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  4. Ensembl
    Submitted (AUG-2015) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PC62_HUMAN
AccessioniPrimary (citable) accession number: E9PC62
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 11, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.