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Protein
Submitted name:

Guanine nucleotide-binding protein subunit alpha-12

Gene

GNA12

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein subunit alpha-12Imported
Gene namesi
Name:GNA12Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:4380. GNA12.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000146535.

PTM / Processingi

Proteomic databases

MaxQBiE9PC54.
PeptideAtlasiE9PC54.
PRIDEiE9PC54.

Expressioni

Gene expression databases

BgeeiENSG00000146535.
ExpressionAtlasiE9PC54. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PC54.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00770000120503.

Family and domain databases

CDDicd00066. G-alpha. 1 hit.
Gene3Di1.10.400.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10218. PTHR10218. 1 hit.
PfamiPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSiPR00318. GPROTEINA.
SMARTiSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PC54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPRAGLGAG PLLLRSRADW VCGGWEAALS APPPFCTAWV ERTGLVHFLR
60 70 80 90 100
EGGHGACFPL ALLHPGSVVS FQMIYPLIVL PLCASWHWGL IRKGIVLFWG
110 120 130 140 150
ESVKYFLDNL DRIGQLNYFP SKQDILLARK ATKGIVEHDF VIKKIPFKMV
160 170 180 190 200
DVGGQRSQRQ KWFQCFDGIT SILFMVSSSE YDQVLMEDRR TNRLVESMNI
210 220 230 240 250
FETIVNNKLF FNVSIILFLN KMDLLVEKVK TVSIKKHFPD FRGDPHRLED
260 270 280 290 300
VQRYLVQCFD RKRRNRSKPL FHHFTTAIDT ENVRFVFHAV KDTILQENLK

DIMLQ
Length:305
Mass (Da):35,196
Last modified:April 5, 2011 - v1
Checksum:i0A76CE1AD141672F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006028 Genomic DNA. No translation available.
RefSeqiNP_001269369.1. NM_001282440.1.
UniGeneiHs.487341.

Genome annotation databases

EnsembliENST00000407653; ENSP00000386054; ENSG00000146535.
GeneIDi2768.
UCSCiuc032zbv.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006028 Genomic DNA. No translation available.
RefSeqiNP_001269369.1. NM_001282440.1.
UniGeneiHs.487341.

3D structure databases

ProteinModelPortaliE9PC54.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE9PC54.
PeptideAtlasiE9PC54.
PRIDEiE9PC54.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000407653; ENSP00000386054; ENSG00000146535.
GeneIDi2768.
UCSCiuc032zbv.2. human.

Organism-specific databases

CTDi2768.
HGNCiHGNC:4380. GNA12.
OpenTargetsiENSG00000146535.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00770000120503.

Miscellaneous databases

ChiTaRSiGNA12. human.
GenomeRNAii2768.

Gene expression databases

BgeeiENSG00000146535.
ExpressionAtlasiE9PC54. baseline and differential.

Family and domain databases

CDDicd00066. G-alpha. 1 hit.
Gene3Di1.10.400.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10218. PTHR10218. 1 hit.
PfamiPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSiPR00318. GPROTEINA.
SMARTiSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE9PC54_HUMAN
AccessioniPrimary (citable) accession number: E9PC54
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 30, 2016
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.