E9PBJ5 (E9PBJ5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Ensembl ENSP00000427703

Gene names

Name:

SDHA Ensembl ENSP00000427703

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000427703

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	616 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000427703

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: InterPro tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-CH group of donors Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9PBJ5 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 7F3417D2C871A210	FASTA	616	67,300
	10 20 30 40 50 60 MSGVRGLSRL LSARRLALAK AWPTVLQTGT RGFHFTVDGN KRASAKVSDS ISAQYPVVDH 70 80 90 100 110 120 EFDAVVVGAG GAGLRAAFGL SEAGFNTACV TKLFPTRSHT VAAQLENYGM PFSRTEDGKI 130 140 150 160 170 180 YQRAFGGQSL KFGKGGQAHR CCCVADRTGH SLLHTLYGRS LRYDTSYFVE YFALDLLMEN 190 200 210 220 230 240 GECRGVIALC IEDGSIHRIR AKNTVVATGG YGRTYFSCTS AHTSTGDGTA MITRAGLPCQ 250 260 270 280 290 300 DLEFVQFHPT GIYGAGCLIT EGCRGEGGIL INSQGERFME RYAPVAKDLA SRDVVSRSMT 310 320 330 340 350 360 LEIREGRGCG PEKDHVYLQL HHLPPEQLAT RLPGISETAM IFAGVDVTKE PIPVLPTVHY 370 380 390 400 410 420 NMGGIPTNYK GQVLRHVNGQ DQIVPGLYAC GEAACASVHG ANRLGANSLL DLVVFGRACA 430 440 450 460 470 480 LSIEESCRPG DKVPPIKPNA GEESVMNLDK LRFADGSIRT SELRLSMQKS MQNHAAVFRV 490 500 510 520 530 540 GSVLQEGCGK ISKLYGDLKH LKTFDRGMVW NTDLVETLEL QNLMLCALQT IYGAEARKES 550 560 570 580 590 600 RGAHAREDYK VRIDEYDYSK PIQGQQKKPF EEHWRKHTLS YVDVGTGKVT LEYRPVIDKT 610 LNEADCATVP PAIRSY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and comparative analysis of human chromosome 5." Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S. , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M. Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC021087 Genomic DNA. No translation available.
IPI	IPI00964764.
3D structure databases
ProteinModelPortal	E9PBJ5.
SMR	E9PBJ5. Positions 52-616.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000510361; ENSP00000427703; ENSG00000073578.
UCSC	uc011clw.2. human.
Organism-specific databases
HGNC	HGNC:10680. SDHA.
GenAtlas	Search...
Gene expression databases
ArrayExpress	E9PBJ5.
Bgee	E9PBJ5.
Family and domain databases
Gene3D	1.20.58.100. 1 hit.
InterPro	IPR003953. FAD_bind_dom. IPR015939. Fum_Rdtase/Succ_DH_flav-like_C. IPR011281. Succ_DH_flav_su_fwd. IPR014006. Succ_Dhase_FrdA_Gneg. [Graphical view]
PANTHER	PTHR11632:SF5. PTHR11632:SF5. 1 hit.
Pfam	PF00890. FAD_binding_2. 1 hit. PF02910. Succ_DH_flav_C. 1 hit. [Graphical view]
SUPFAM	SSF46977. Succ_DH_flav_C. 1 hit.
TIGRFAMs	TIGR01816. sdhA_forward. 1 hit. TIGR01812. sdhA_frdA_Gneg. 1 hit.
ProtoNet	Search...
Other
NextBio	35501424.

Entry information

Entry name

E9PBJ5_HUMAN

Accession

Primary (citable) accession number: E9PBJ5

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.