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E9PBI9

- E9PBI9_HUMAN

UniProt

E9PBI9 - E9PBI9_HUMAN

Protein

Syndecan

Gene

SDC2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Cell surface proteoglycan.UniRule annotation

    GO - Biological processi

    1. dendrite morphogenesis Source: Ensembl
    2. regulation of dendrite morphogenesis Source: Ensembl
    3. response to caffeine Source: Ensembl
    4. response to hypoxia Source: Ensembl
    5. wound healing Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    SyndecanUniRule annotation
    Gene namesi
    Name:SDC2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 8

    Organism-specific databases

    HGNCiHGNC:10659. SDC2.

    Subcellular locationi

    Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. neuronal cell body Source: Ensembl

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Keywords - PTMi

    Glycoprotein, Heparan sulfateUniRule annotation, Proteoglycan

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the syndecan proteoglycan family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    KOiK16336.

    Family and domain databases

    InterProiIPR003585. Neurexin-like.
    IPR001050. Syndecan.
    IPR027789. Syndecan/Neurexin_dom.
    [Graphical view]
    PANTHERiPTHR10915. PTHR10915. 1 hit.
    PfamiPF01034. Syndecan. 1 hit.
    [Graphical view]
    SMARTiSM00294. 4.1m. 1 hit.
    [Graphical view]
    PROSITEiPS00964. SYNDECAN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9PBI9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYLDNSSIEE ASGVYPIDDD DYASASGSGA DEDVESPELT TSRPLPKILL    50
    TSAAPKVETT TLNIQNKIPA QTKSPEETDK EKVHLSDSER KMDPAEEDTN 100
    VYTEKHSDSL FKRTEVLAAV IAGGVIGFLF AIFLILLLVY RMRKKDEGSY 150
    DLGERKPSSA AYQKAPTKEF YA 172
    Length:172
    Mass (Da):18,972
    Last modified:April 5, 2011 - v1
    Checksum:i616D44AC7977D6A2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP003477 Genomic DNA. No translation available.
    AP003548 Genomic DNA. No translation available.
    KC877279 Genomic DNA. No translation available.
    RefSeqiXP_005251077.1. XM_005251020.2.
    XP_006716677.1. XM_006716614.1.
    UniGeneiHs.1501.
    Hs.598247.

    Genome annotation databases

    EnsembliENST00000519914; ENSP00000428256; ENSG00000169439.
    ENST00000522911; ENSP00000427784; ENSG00000169439.
    GeneIDi6383.
    KEGGihsa:6383.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP003477 Genomic DNA. No translation available.
    AP003548 Genomic DNA. No translation available.
    KC877279 Genomic DNA. No translation available.
    RefSeqi XP_005251077.1. XM_005251020.2.
    XP_006716677.1. XM_006716614.1.
    UniGenei Hs.1501.
    Hs.598247.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000519914 ; ENSP00000428256 ; ENSG00000169439 .
    ENST00000522911 ; ENSP00000427784 ; ENSG00000169439 .
    GeneIDi 6383.
    KEGGi hsa:6383.

    Organism-specific databases

    CTDi 6383.
    HGNCi HGNC:10659. SDC2.
    GenAtlasi Search...

    Phylogenomic databases

    KOi K16336.

    Miscellaneous databases

    GenomeRNAii 6383.
    NextBioi 35501421.

    Family and domain databases

    InterProi IPR003585. Neurexin-like.
    IPR001050. Syndecan.
    IPR027789. Syndecan/Neurexin_dom.
    [Graphical view ]
    PANTHERi PTHR10915. PTHR10915. 1 hit.
    Pfami PF01034. Syndecan. 1 hit.
    [Graphical view ]
    SMARTi SM00294. 4.1m. 1 hit.
    [Graphical view ]
    PROSITEi PS00964. SYNDECAN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence and analysis of human chromosome 8."
      Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T.
      , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S.
      Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
    5. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE9PBI9_HUMAN
    AccessioniPrimary (citable) accession number: E9PBI9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3