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E9PBE2

- E9PBE2_HUMAN

UniProt

E9PBE2 - E9PBE2_HUMAN

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Protein
Submitted name:

Signal transducer and activator of transcription 4

Gene
STAT4
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: Ensembl
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
  3. signal transducer activity Source: InterPro

GO - Biological processi

  1. cell proliferation Source: Ensembl
  2. cytokine-mediated signaling pathway Source: Ensembl
  3. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  4. protein phosphorylation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Signal transducer and activator of transcription 4Imported
Gene namesi
Name:STAT4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:11365. STAT4.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiE9PBE2.
BgeeiE9PBE2.

Structurei

3D structure databases

ProteinModelPortaliE9PBE2.
SMRiE9PBE2. Positions 2-79.

Family & Domainsi

Family and domain databases

Gene3Di1.10.532.10. 1 hit.
InterProiIPR001217. STAT.
IPR013799. STAT_TF_prot_interaction.
[Graphical view]
PANTHERiPTHR11801. PTHR11801. 1 hit.
PfamiPF02865. STAT_int. 1 hit.
[Graphical view]
SUPFAMiSSF48092. SSF48092. 1 hit.

Sequencei

Sequence statusi: Fragment.

E9PBE2-1 [UniParc]FASTAAdd to Basket

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MSQWNQVQQL EIKFLEQVDQ FYDDNFPMEI RHLLAQWIEN QDWEAASNNE   50
TMATILLQNL LIQLDEQLGR VSKEKNLLL 79
Length:79
Mass (Da):9,462
Last modified:April 5, 2011 - v1
Checksum:iC1D745781DDE13E7
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei79 – 791Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC067945 Genomic DNA. No translation available.
AC079777 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000450994; ENSP00000412397; ENSG00000138378.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC067945 Genomic DNA. No translation available.
AC079777 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E9PBE2.
SMRi E9PBE2. Positions 2-79.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000450994 ; ENSP00000412397 ; ENSG00000138378 .

Organism-specific databases

HGNCi HGNC:11365. STAT4.
GenAtlasi Search...

Miscellaneous databases

NextBioi 35501405.

Gene expression databases

ArrayExpressi E9PBE2.
Bgeei E9PBE2.

Family and domain databases

Gene3Di 1.10.532.10. 1 hit.
InterProi IPR001217. STAT.
IPR013799. STAT_TF_prot_interaction.
[Graphical view ]
PANTHERi PTHR11801. PTHR11801. 1 hit.
Pfami PF02865. STAT_int. 1 hit.
[Graphical view ]
SUPFAMi SSF48092. SSF48092. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PBE2_HUMAN
AccessioniPrimary (citable) accession number: E9PBE2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 9, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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