Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

THO complex subunit 4

Gene

ALYREF

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
THO complex subunit 4Imported
Gene namesi
Name:ALYREFImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000183684.7
HGNCiHGNC:19071 ALYREF

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000183684

PTM / Processingi

Proteomic databases

EPDiE9PB61
MaxQBiE9PB61
PeptideAtlasiE9PB61
PRIDEiE9PB61

Expressioni

Gene expression databases

BgeeiENSG00000183684
GenevisibleiE9PB61 HS

Interactioni

Protein-protein interaction databases

IntActiE9PB61, 6 interactors

Structurei

3D structure databases

ProteinModelPortaliE9PB61
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini113 – 190RRMInterPro annotationAdd BLAST78

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili240 – 264Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0533 Eukaryota
ENOG4111JAW LUCA
GeneTreeiENSGT00410000025615
KOiK12881
OMAiYTRGDVN
OrthoDBiEOG091G0T4Z
PhylomeDBiE9PB61
TreeFamiTF313312

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR025715 FoP_C
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF13865 FoP_duplication, 1 hit
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM01218 FoP_duplication, 1 hit
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequencei

Sequence statusi: Complete.

E9PB61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPDSAPAMAD KMDMSLDDII KLNRSQRGGR GGGRGRGRAG SQGGRGGGAQ
60 70 80 90 100
AAARVNRGGG PIRNRPAIAR GAAGGGGRNR PAPYSRPKQL PDKWQHDLFD
110 120 130 140 150
SGFGGGAGVE TGGKLLVSNL DFGVSDADIQ ELFAEFGTLK KAAVHYDRSG
160 170 180 190 200
RSLGTADVHF ERKADALKAM KQYNGVPLDG RPMNIQLVTS QIDAQRRPAQ
210 220 230 240 250
SVNRGGMTRN RGAGGFGGGG GTRRGTRGGA RGRGRGAGRN SKQQLSAEEL
260
DAQLDAYNAR MDTS
Length:264
Mass (Da):27,558
Last modified:April 5, 2011 - v1
Checksum:i52BEF28686C9EB04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC145207 Genomic DNA No translation available.
RefSeqiNP_005773.3, NM_005782.3
UniGeneiHs.534385

Genome annotation databases

EnsembliENST00000505490; ENSP00000421592; ENSG00000183684
GeneIDi10189
KEGGihsa:10189
UCSCiuc002kbu.3 human

Similar proteinsi

Entry informationi

Entry nameiE9PB61_HUMAN
AccessioniPrimary (citable) accession number: E9PB61
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 25, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health