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Protein
Submitted name:

cAMP-responsive element modulator

Gene

CREM

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cAMP-responsive element modulatorImported
Gene namesi
Name:CREMImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:2352. CREM.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000095794.

PTM / Processingi

Proteomic databases

MaxQBiE9PB41.
PaxDbiE9PB41.
PeptideAtlasiE9PB41.

Expressioni

Gene expression databases

BgeeiENSG00000095794.
ExpressionAtlasiE9PB41. baseline and differential.
GenevisibleiE9PB41. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000265372.

Structurei

3D structure databases

ProteinModelPortaliE9PB41.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 88BZIP (basic-leucine zipper)InterPro annotationAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili62 – 89Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3584. Eukaryota.
ENOG410ZZJZ. LUCA.
GeneTreeiENSGT00390000008655.

Family and domain databases

InterProiIPR004827. bZIP.
IPR001630. Leuzip_CREB.
[Graphical view]
PfamiPF00170. bZIP_1. 1 hit.
[Graphical view]
PRINTSiPR00041. LEUZIPPRCREB.
SMARTiSM00338. BRLZ. 1 hit.
[Graphical view]
PROSITEiPS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PB41-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTYQIRAPT AALPQGVVMA ASPGSLHSPQ QLAEEATRKR ELRLMKNREA
60 70 80 90
AKECRRRKKE YVKCLESRVA VLEVQNKKLI EELETLKDIC SPKTDY
Length:96
Mass (Da):10,969
Last modified:April 5, 2011 - v1
Checksum:iF892E56D09734983
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117336 Genomic DNA. No translation available.
AL157783 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000474362; ENSP00000419018; ENSG00000095794.
UCSCiuc001ixy.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117336 Genomic DNA. No translation available.
AL157783 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9PB41.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000265372.

Proteomic databases

MaxQBiE9PB41.
PaxDbiE9PB41.
PeptideAtlasiE9PB41.

Protocols and materials databases

DNASUi1390.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000474362; ENSP00000419018; ENSG00000095794.
UCSCiuc001ixy.4. human.

Organism-specific databases

HGNCiHGNC:2352. CREM.
OpenTargetsiENSG00000095794.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3584. Eukaryota.
ENOG410ZZJZ. LUCA.
GeneTreeiENSGT00390000008655.

Miscellaneous databases

ChiTaRSiCREM. human.

Gene expression databases

BgeeiENSG00000095794.
ExpressionAtlasiE9PB41. baseline and differential.
GenevisibleiE9PB41. HS.

Family and domain databases

InterProiIPR004827. bZIP.
IPR001630. Leuzip_CREB.
[Graphical view]
PfamiPF00170. bZIP_1. 1 hit.
[Graphical view]
PRINTSiPR00041. LEUZIPPRCREB.
SMARTiSM00338. BRLZ. 1 hit.
[Graphical view]
PROSITEiPS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9PB41_HUMAN
AccessioniPrimary (citable) accession number: E9PB41
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 30, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.