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E9PB15 (PTG3L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative protein PTGES3L
Alternative name(s):
Prostaglandin E synthase 3-like
Gene names
Name:PTGES3L
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length166 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Sequence similarities

Belongs to the p23/wos2 family.

Contains 1 CS domain.

Caution

Product of a dubious gene prediction.

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: E9PB15-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9BTE6-2)

The sequence of this isoform can be found in the external entry Q9BTE6.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Based on a readthrough transcript which may produce a PTGES3L-AARSD1 fusion protein. No experimental confirmation available.
Isoform 3 (identifier: Q9BTE6-3)

The sequence of this isoform can be found in the external entry Q9BTE6.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Based on a readthrough transcript which may produce a PTGES3L-AARSD1 fusion protein. No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 166166Putative protein PTGES3L
PRO_0000418440

Regions

Domain46 – 154109CS

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: F960941BA0FC90C1

FASTA16619,074
        10         20         30         40         50         60 
MFSLPLNCSP DHIRRGSCWG RPQDLKIAAP AWNSKCHPGA GAAMARQHAR TLWYDRPRYV 

        70         80         90        100        110        120 
FMEFCVEDST DVHVLIEDHR IVFSCKNADG VELYNEIEFY AKVNSKPVWL SVDFDNWRDW 

       130        140        150        160 
EGDEEMELAH VEHYAELLKK VSTKRPPPAM DDLDDDSDSA DDATSN 

« Hide

Isoform 2 [UniParc].

See Q9BTE6.

Isoform 3 [UniParc].

See Q9BTE6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC055866 Genomic DNA. No translation available.
RefSeqNP_001136125.1. NM_001142653.1.
UniGeneHs.317403.

3D structure databases

ProteinModelPortalE9PB15.
SMRE9PB15. Positions 47-121.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

DNASU80755.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000453594; ENSP00000394415; ENSG00000267060. [E9PB15-1]
GeneID100885848.
KEGGhsa:100885848.
UCSCuc010whh.2. human. [E9PB15-1]

Organism-specific databases

CTD100885848.
GeneCardsGC17M041120.
HGNCHGNC:43943. PTGES3L.
neXtProtNX_E9PB15.
GenAtlasSearch...

Gene expression databases

ArrayExpressE9PB15.
BgeeE9PB15.

Family and domain databases

Gene3D2.60.40.790. 1 hit.
InterProIPR007052. CS_dom.
IPR008978. HSP20-like_chaperone.
[Graphical view]
SUPFAMSSF49764. SSF49764. 1 hit.
PROSITEPS51203. CS. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi100885848.
NextBio34057621.

Entry information

Entry namePTG3L_HUMAN
AccessionPrimary (citable) accession number: E9PB15
Entry history
Integrated into UniProtKB/Swiss-Prot: September 5, 2012
Last sequence update: April 5, 2011
Last modified: April 16, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 17

Human chromosome 17: entries, gene names and cross-references to MIM