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E9PAW7

- E9PAW7_HUMAN

UniProt

E9PAW7 - E9PAW7_HUMAN

Protein
Submitted name:

Transforming growth factor beta receptor type 3

Gene

TGFBR3

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. heparin binding Source: Ensembl
    2. transforming growth factor beta receptor activity, type III Source: Ensembl

    GO - Biological processi

    1. blastocyst development Source: Ensembl
    2. blood vessel development Source: Ensembl
    3. cardiac muscle cell proliferation Source: Ensembl
    4. cell growth Source: Ensembl
    5. definitive erythrocyte differentiation Source: Ensembl
    6. heart trabecula formation Source: Ensembl
    7. liver development Source: Ensembl
    8. negative regulation of epithelial cell migration Source: Ensembl
    9. negative regulation of epithelial cell proliferation Source: Ensembl
    10. negative regulation of epithelial to mesenchymal transition Source: Ensembl
    11. negative regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
    12. organ regeneration Source: Ensembl
    13. palate development Source: Ensembl
    14. pathway-restricted SMAD protein phosphorylation Source: Ensembl
    15. positive regulation of NF-kappaB transcription factor activity Source: Ensembl
    16. positive regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
    17. regulation of protein binding Source: Ensembl
    18. response to hypoxia Source: Ensembl
    19. transforming growth factor beta receptor complex assembly Source: Ensembl
    20. ventricular cardiac muscle tissue morphogenesis Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Transforming growth factor beta receptor type 3Imported
    Gene namesi
    Name:TGFBR3Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:11774. TGFBR3.

    Subcellular locationi

    GO - Cellular componenti

    1. cell surface Source: Ensembl
    2. endoplasmic reticulum Source: Ensembl
    3. extracellular space Source: Ensembl
    4. integral component of plasma membrane Source: Ensembl
    5. proteinaceous extracellular matrix Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiE9PAW7.
    BgeeiE9PAW7.

    Sequencei

    Sequence statusi: Fragment.

    E9PAW7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTSHYVIAIF ALMSSCLATA GPEPGALCEL SPVSA                   35
    Length:35
    Mass (Da):3,539
    Last modified:April 5, 2011 - v1
    Checksum:iDF8723B4E17A6464
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei35 – 351Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC099334 Genomic DNA. No translation available.
    AC114486 Genomic DNA. No translation available.
    AL162263 Genomic DNA. No translation available.
    AL390780 Genomic DNA. No translation available.
    AL445992 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000417833; ENSP00000395975; ENSG00000069702.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC099334 Genomic DNA. No translation available.
    AC114486 Genomic DNA. No translation available.
    AL162263 Genomic DNA. No translation available.
    AL390780 Genomic DNA. No translation available.
    AL445992 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000417833 ; ENSP00000395975 ; ENSG00000069702 .

    Organism-specific databases

    HGNCi HGNC:11774. TGFBR3.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi TGFBR3. human.
    NextBioi 35501365.

    Gene expression databases

    ArrayExpressi E9PAW7.
    Bgeei E9PAW7.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
      , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E.
      Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE9PAW7_HUMAN
    AccessioniPrimary (citable) accession number: E9PAW7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 19 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3