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E9PAW7

- E9PAW7_HUMAN

UniProt

E9PAW7 - E9PAW7_HUMAN

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Protein
Submitted name:

Transforming growth factor beta receptor type 3

Gene

TGFBR3

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. heparin binding Source: Ensembl
  2. transforming growth factor beta receptor activity, type III Source: Ensembl

GO - Biological processi

  1. blastocyst development Source: Ensembl
  2. blood vessel development Source: Ensembl
  3. cardiac muscle cell proliferation Source: Ensembl
  4. cell growth Source: Ensembl
  5. definitive erythrocyte differentiation Source: Ensembl
  6. heart trabecula formation Source: Ensembl
  7. liver development Source: Ensembl
  8. negative regulation of epithelial cell migration Source: Ensembl
  9. negative regulation of epithelial cell proliferation Source: Ensembl
  10. negative regulation of epithelial to mesenchymal transition Source: Ensembl
  11. negative regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  12. organ regeneration Source: Ensembl
  13. palate development Source: Ensembl
  14. pathway-restricted SMAD protein phosphorylation Source: Ensembl
  15. positive regulation of NF-kappaB transcription factor activity Source: Ensembl
  16. positive regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  17. regulation of protein binding Source: Ensembl
  18. response to hypoxia Source: Ensembl
  19. transforming growth factor beta receptor complex assembly Source: Ensembl
  20. ventricular cardiac muscle tissue morphogenesis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transforming growth factor beta receptor type 3Imported
Gene namesi
Name:TGFBR3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:11774. TGFBR3.

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: Ensembl
  2. endoplasmic reticulum Source: Ensembl
  3. extracellular space Source: Ensembl
  4. integral component of plasma membrane Source: Ensembl
  5. proteinaceous extracellular matrix Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE9PAW7.
ExpressionAtlasiE9PAW7. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063861.

Sequencei

Sequence statusi: Fragment.

E9PAW7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30
MTSHYVIAIF ALMSSCLATA GPEPGALCEL SPVSA
Length:35
Mass (Da):3,539
Last modified:April 5, 2011 - v1
Checksum:iDF8723B4E17A6464
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei35 – 351Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC099334 Genomic DNA. No translation available.
AC114486 Genomic DNA. No translation available.
AL162263 Genomic DNA. No translation available.
AL390780 Genomic DNA. No translation available.
AL445992 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000417833; ENSP00000395975; ENSG00000069702.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC099334 Genomic DNA. No translation available.
AC114486 Genomic DNA. No translation available.
AL162263 Genomic DNA. No translation available.
AL390780 Genomic DNA. No translation available.
AL445992 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000417833 ; ENSP00000395975 ; ENSG00000069702 .

Organism-specific databases

HGNCi HGNC:11774. TGFBR3.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00530000063861.

Miscellaneous databases

ChiTaRSi TGFBR3. human.
NextBioi 35501365.

Gene expression databases

Bgeei E9PAW7.
ExpressionAtlasi E9PAW7. baseline and differential.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PAW7_HUMAN
AccessioniPrimary (citable) accession number: E9PAW7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3