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Protein
Submitted name:

CASP8 and FADD-like apoptosis regulator

Gene

CFLAR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CASP8 and FADD-like apoptosis regulatorImported
Gene namesi
Name:CFLARImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000003402.19
HGNCiHGNC:1876 CFLAR

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000003402

PTM / Processingi

Proteomic databases

MaxQBiE9PAP3
PeptideAtlasiE9PAP3
PRIDEiE9PAP3

Expressioni

Gene expression databases

BgeeiENSG00000003402
ExpressionAtlasiE9PAP3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PAP3
SMRiE9PAP3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 73DEDInterPro annotationAdd BLAST73
Domaini92 – 170DEDInterPro annotationAdd BLAST79

Phylogenomic databases

eggNOGiKOG3573 Eukaryota
ENOG410ZQIE LUCA
GeneTreeiENSGT00530000064199

Family and domain databases

InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR001875 DED_dom
PfamiView protein in Pfam
PF01335 DED, 2 hits
SMARTiView protein in SMART
SM00031 DED, 2 hits
SUPFAMiSSF47986 SSF47986, 2 hits
PROSITEiView protein in PROSITE
PS50168 DED, 2 hits

Sequencei

Sequence statusi: Complete.

E9PAP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAEVIHQVE EALDTDEKEM LLFLCRDVAI DVVPPNVRDL LDILRERGKL
60 70 80 90 100
SVGDLAELLY RVRRFDLLKR ILKMDRKAVE THLLRNPHLV SDYRVLMAEI
110 120 130 140 150
GEDLDKSDVS SLIFLMKDYM GRGKISKEKS FLDLVVELEK LNLVAPDQLD
160 170 180 190 200
LLEKCLKNIH RIDLKTKIQK YKQSGGWNGT WMTKASFSLW LEIASLYILH
210 220 230 240 250
IPDLPTPLPC IFMISAKCCQ AVLNISVFKK ESGICTGWQS YGHSGVLHVC
Length:250
Mass (Da):28,584
Last modified:April 5, 2011 - v1
Checksum:iC5B5FEC0DD80FDF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007283 Genomic DNA No translation available.
RefSeqiNP_001294972.1, NM_001308043.1
UniGeneiHs.390736
Hs.731912

Genome annotation databases

EnsembliENST00000395148; ENSP00000378580; ENSG00000003402
GeneIDi8837
UCSCiuc002uwy.4 human

Similar proteinsi

Entry informationi

Entry nameiE9PAP3_HUMAN
AccessioniPrimary (citable) accession number: E9PAP3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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