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E9PAP3

- E9PAP3_HUMAN

UniProt

E9PAP3 - E9PAP3_HUMAN

Protein
Submitted name:

CASP8 and FADD-like apoptosis regulator

Gene

CFLAR

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. regulation of apoptotic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CASP8 and FADD-like apoptosis regulatorImported
    Gene namesi
    Name:CFLARImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:1876. CFLAR.

    PTM / Processingi

    Proteomic databases

    PRIDEiE9PAP3.

    Expressioni

    Gene expression databases

    ArrayExpressiE9PAP3.
    BgeeiE9PAP3.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PAP3.
    SMRiE9PAP3. Positions 4-169.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK04724.
    OMAiLYILHIP.

    Family and domain databases

    Gene3Di1.10.533.10. 2 hits.
    InterProiIPR011029. DEATH-like_dom.
    IPR001875. DED.
    [Graphical view]
    PfamiPF01335. DED. 2 hits.
    [Graphical view]
    SMARTiSM00031. DED. 2 hits.
    [Graphical view]
    SUPFAMiSSF47986. SSF47986. 2 hits.
    PROSITEiPS50168. DED. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9PAP3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAEVIHQVE EALDTDEKEM LLFLCRDVAI DVVPPNVRDL LDILRERGKL    50
    SVGDLAELLY RVRRFDLLKR ILKMDRKAVE THLLRNPHLV SDYRVLMAEI 100
    GEDLDKSDVS SLIFLMKDYM GRGKISKEKS FLDLVVELEK LNLVAPDQLD 150
    LLEKCLKNIH RIDLKTKIQK YKQSGGWNGT WMTKASFSLW LEIASLYILH 200
    IPDLPTPLPC IFMISAKCCQ AVLNISVFKK ESGICTGWQS YGHSGVLHVC 250
    Length:250
    Mass (Da):28,584
    Last modified:April 5, 2011 - v1
    Checksum:iC5B5FEC0DD80FDF5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007283 Genomic DNA. No translation available.
    RefSeqiXP_005246995.1. XM_005246938.1.
    UniGeneiHs.390736.
    Hs.731912.

    Genome annotation databases

    EnsembliENST00000395148; ENSP00000378580; ENSG00000003402.
    GeneIDi8837.
    KEGGihsa:8837.
    UCSCiuc002uwy.3. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007283 Genomic DNA. No translation available.
    RefSeqi XP_005246995.1. XM_005246938.1.
    UniGenei Hs.390736.
    Hs.731912.

    3D structure databases

    ProteinModelPortali E9PAP3.
    SMRi E9PAP3. Positions 4-169.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi E9PAP3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000395148 ; ENSP00000378580 ; ENSG00000003402 .
    GeneIDi 8837.
    KEGGi hsa:8837.
    UCSCi uc002uwy.3. human.

    Organism-specific databases

    CTDi 8837.
    HGNCi HGNC:1876. CFLAR.
    GenAtlasi Search...

    Phylogenomic databases

    KOi K04724.
    OMAi LYILHIP.

    Miscellaneous databases

    ChiTaRSi CFLAR. human.
    GenomeRNAii 8837.
    NextBioi 35501357.

    Gene expression databases

    ArrayExpressi E9PAP3.
    Bgeei E9PAP3.

    Family and domain databases

    Gene3Di 1.10.533.10. 2 hits.
    InterProi IPR011029. DEATH-like_dom.
    IPR001875. DED.
    [Graphical view ]
    Pfami PF01335. DED. 2 hits.
    [Graphical view ]
    SMARTi SM00031. DED. 2 hits.
    [Graphical view ]
    SUPFAMi SSF47986. SSF47986. 2 hits.
    PROSITEi PS50168. DED. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE9PAP3_HUMAN
    AccessioniPrimary (citable) accession number: E9PAP3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3