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E9LRR8

- E9LRR8_HUMAN

UniProt

E9LRR8 - E9LRR8_HUMAN

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Protein
Submitted name: POU domain transcription factor OCT4-pg4
Gene
POU5F1P4
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotations

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    POU domain transcription factor OCT4-pg4Imported
    Gene namesi
    Name:POU5F1P4Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    Nucleus By similarity UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    NucleusUniRule annotationSAAS annotations

    Family & Domainsi

    Sequence similaritiesi

    Contains POU-specific domain.SAAS annotations
    Contains homeobox DNA-binding domain.SAAS annotations

    Keywords - Domaini

    HomeoboxUniRule annotationSAAS annotations

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProiIPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR015585. POU_dom_5.
    IPR000327. POU_specific.
    [Graphical view]
    PANTHERiPTHR11636:SF15. PTHR11636:SF15. 1 hit.
    PfamiPF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view]
    PRINTSiPR00028. POUDOMAIN.
    SMARTiSM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00035. POU_1. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9LRR8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPAFLPPPGG GGDGPGGPEP GWVDPRTWLS FQGPPGGPGI GPGVGSGSEV    50
    WGIPPCPPLY EFCGGMAYCG PQVGVRLVPQ GGLETSQPEG EAGVRVESNS 100
    DGTSLEPCTV PPGAVKLEKE KLEQNPQESQ NIKALQKELE QFAKLLKQKR 150
    ITLGYTQADV GLTLGVLFGK VFSQTTICRF EGLQLSFKNV CKLRPLLQKW 200
    VEEADNNENL QETCKAETLL QARKRKRTSI ENRVRGNLEN LFLQCPKPTL 250
    QQISHIAQQL GLEKDVVRVW FCNRCQKGKQ SSSDYA 286
    Length:286
    Mass (Da):31,127
    Last modified:April 5, 2011 - v1
    Checksum:iB741539DB46EA044
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HQ122888 mRNA. Translation: ADW77508.1.
    HQ122889 mRNA. Translation: ADW77509.1.
    HQ122890 mRNA. Translation: ADW77510.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HQ122888 mRNA. Translation: ADW77508.1 .
    HQ122889 mRNA. Translation: ADW77509.1 .
    HQ122890 mRNA. Translation: ADW77510.1 .

    3D structure databases

    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    NextBioi 35501173.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProi IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR015585. POU_dom_5.
    IPR000327. POU_specific.
    [Graphical view ]
    PANTHERi PTHR11636:SF15. PTHR11636:SF15. 1 hit.
    Pfami PF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view ]
    PRINTSi PR00028. POUDOMAIN.
    SMARTi SM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00035. POU_1. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Expression of OCT4 pseudogenes in two human somatic tumours: glioma and breast carcinoma."
      Zhao S., Yuan Q., Guo Y., Liu S., Zhang Y., Wang J., Liu H., Wang F., Liu K., Ling E.-A., Hao A.
      Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Breast cancer HER2+ subtypeImported.

    Entry informationi

    Entry nameiE9LRR8_HUMAN
    AccessioniPrimary (citable) accession number: E9LRR8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: June 11, 2014
    This is version 15 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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