UniProtKB - E9LR91 (E9LR91_HUMAN)
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Protein
POU domain protein
Gene
POU5F1P4
Organism
Homo sapiens (Human)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 223 – 282 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 60 |
GO - Molecular functioni
- DNA binding transcription factor activity Source: UniProtKB-UniRule
- sequence-specific DNA binding Source: InterPro
GO - Biological processi
- transcription, DNA-templated Source: UniProtKB-UniRule
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationSAAS annotation |
Biological process | Transcription, Transcription regulationPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: POU domain proteinUniRule annotation |
Gene namesi | Name:POU5F1P4Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationSAAS annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 131 – 205 | POU-specificInterPro annotationAdd BLAST | 75 | |
Domaini | 221 – 281 | HomeoboxInterPro annotationAdd BLAST | 61 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 132 – 152 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysis, HomeoboxPROSITE-ProRule annotationSAAS annotationFamily and domain databases
CDDi | cd00086. homeodomain. 1 hit. |
InterProi | View protein in InterPro IPR009057. Homeobox-like_sf. IPR017970. Homeobox_CS. IPR001356. Homeobox_dom. IPR010982. Lambda_DNA-bd_dom_sf. IPR013847. POU. IPR000327. POU_dom. IPR015585. POU_dom_5. |
PANTHERi | PTHR11636:SF86. PTHR11636:SF86. 1 hit. |
Pfami | View protein in Pfam PF00046. Homeobox. 1 hit. PF00157. Pou. 1 hit. |
PRINTSi | PR00028. POUDOMAIN. |
SMARTi | View protein in SMART SM00389. HOX. 1 hit. SM00352. POU. 1 hit. |
SUPFAMi | SSF46689. SSF46689. 1 hit. SSF47413. SSF47413. 1 hit. |
PROSITEi | View protein in PROSITE PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS00035. POU_1. 1 hit. PS00465. POU_2. 1 hit. PS51179. POU_3. 1 hit. |
i Sequence
Sequence statusi: Complete.
E9LR91-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPAFLPPPGG GGDGPGGPEP GWVDPRTWLS FQGPPGGPGI GPGVGSGSEV
60 70 80 90 100
WGIPPCPPLY EFCGGMAYCG PQVGVRLVPQ GGLETSQPEG EAGVRVESNS
110 120 130 140 150
DGTSLEPCTV PPGAVKLEKE KLEQNPQESQ NIKALQKELE QFAKLLKQKR
160 170 180 190 200
ITLGYTQADV GHTLGVLFGK VFSQTTICRF EGLQLSFKNM CKLRPLLQKW
210 220 230 240 250
VEEADNNENL QETCKAETLL QARKRKRTSI ENRVRGSLEN LFLQCPKPTL
260 270 280
QQISHIAQQL GLEKDVVRVW FCNRCQKGKQ SSSDYA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HQ122682 mRNA. Translation: ADW77331.1. |
UniGenei | Hs.632482. |
Similar proteinsi
Entry informationi
Entry namei | E9LR91_HUMAN | |
Accessioni | E9LR91Primary (citable) accession number: E9LR91 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 5, 2011 |
Last sequence update: | April 5, 2011 | |
Last modified: | March 28, 2018 | |
This is version 47 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |