ID   E9LHD1_CHICK            Unreviewed;       193 AA.
AC   E9LHD1;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   24-JAN-2024, entry version 50.
DE   SubName: Full=Interferon-alpha {ECO:0000313|EMBL:ADU60333.1};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031 {ECO:0000313|EMBL:ADU60333.1};
RN   [1] {ECO:0000313|EMBL:ADU60333.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Yu X., Sheng Z., Wang J.;
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Has antiviral activities. {ECO:0000256|ARBA:ARBA00002718}.
CC   -!- SIMILARITY: Belongs to the alpha/beta interferon family.
CC       {ECO:0000256|ARBA:ARBA00011033, ECO:0000256|RuleBase:RU000436}.
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DR   EMBL; HQ008781; ADU60333.1; -; mRNA.
DR   AlphaFoldDB; E9LHD1; -.
DR   VEuPathDB; HostDB:geneid_396398; -.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR   GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR   GO; GO:0005126; F:cytokine receptor binding; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   CDD; cd00095; IFab; 1.
DR   Gene3D; 1.20.1250.10; -; 1.
DR   InterPro; IPR009079; 4_helix_cytokine-like_core.
DR   InterPro; IPR000471; Interferon_alpha/beta/delta.
DR   PANTHER; PTHR11691:SF37; INTERFERON OMEGA-1; 1.
DR   PANTHER; PTHR11691; TYPE I INTERFERON; 1.
DR   Pfam; PF00143; Interferon; 1.
DR   PRINTS; PR00266; INTERFERONAB.
DR   SMART; SM00076; IFabd; 1.
DR   SUPFAM; SSF47266; 4-helical cytokines; 1.
DR   PROSITE; PS00252; INTERFERON_A_B_D; 1.
PE   2: Evidence at transcript level;
KW   Antiviral defense {ECO:0000256|ARBA:ARBA00023118,
KW   ECO:0000256|RuleBase:RU000436}; Cytokine {ECO:0000256|RuleBase:RU000436};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           32..193
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003241698"
SQ   SEQUENCE   193 AA;  22100 MW;  59A6344ED5191F40 CRC64;
     MAVPASPQHP RGYGIPLLTL LLKALATTAS ACNHLRPQDA TFSHDSLQLL RDMAPTLPQL
     CPQHNASCSF NDTILDTSNT RQADKTTHDI LQHLFKILSS PSTPAHWNDS QRQSLLNRIH
     RYTQHLEQCL DSSDTRSRTR WPRNLHLTIK KHFSCLHTFL QDNDYSACAW EHVRLQARAW
     FLHIHNLTGN TRT
//