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Protein
Submitted name:

Interferon-alpha

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processAntiviral defenseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon-alphaImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_500324169832 – 193Sequence analysisAdd BLAST162

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiE9LHD1.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000021594.

Family & Domainsi

Sequence similaritiesi

Belongs to the alpha/beta interferon family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

CDDicd00095. IFab. 1 hit.
Gene3Di1.20.1250.10. 1 hit.
InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR000471. Interferon_alpha/beta/delta.
IPR015588. Interferon_beta.
PANTHERiPTHR11691. PTHR11691. 1 hit.
PTHR11691:SF56. PTHR11691:SF56. 1 hit.
PfamiView protein in Pfam
PF00143. Interferon. 1 hit.
PRINTSiPR00266. INTERFERONAB.
SMARTiView protein in SMART
SM00076. IFabd. 1 hit.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00252. INTERFERON_A_B_D. 1 hit.

Sequencei

Sequence statusi: Complete.

E9LHD1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVPASPQHP RGYGIPLLTL LLKALATTAS ACNHLRPQDA TFSHDSLQLL
60 70 80 90 100
RDMAPTLPQL CPQHNASCSF NDTILDTSNT RQADKTTHDI LQHLFKILSS
110 120 130 140 150
PSTPAHWNDS QRQSLLNRIH RYTQHLEQCL DSSDTRSRTR WPRNLHLTIK
160 170 180 190
KHFSCLHTFL QDNDYSACAW EHVRLQARAW FLHIHNLTGN TRT
Length:193
Mass (Da):22,100
Last modified:April 5, 2011 - v1
Checksum:i59A6344ED5191F40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ008781 mRNA. Translation: ADU60333.1.
UniGeneiGga.801.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ008781 mRNA. Translation: ADU60333.1.
UniGeneiGga.801.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000021594.

Proteomic databases

PaxDbiE9LHD1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd00095. IFab. 1 hit.
Gene3Di1.20.1250.10. 1 hit.
InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR000471. Interferon_alpha/beta/delta.
IPR015588. Interferon_beta.
PANTHERiPTHR11691. PTHR11691. 1 hit.
PTHR11691:SF56. PTHR11691:SF56. 1 hit.
PfamiView protein in Pfam
PF00143. Interferon. 1 hit.
PRINTSiPR00266. INTERFERONAB.
SMARTiView protein in SMART
SM00076. IFabd. 1 hit.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00252. INTERFERON_A_B_D. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE9LHD1_CHICK
AccessioniPrimary (citable) accession number: E9LHD1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 15, 2017
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.