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Protein
Submitted name:

Epididymis tissue protein Li 173

Gene

SERPING1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Protein family/group databases

MEROPSiI04.024.

Names & Taxonomyi

Protein namesi
Submitted name:
Epididymis tissue protein Li 173Imported
Submitted name:
Serpin peptidase inhibitor clade G member 1 isoform 1Imported
Gene namesi
Name:SERPING1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 500478Sequence analysisPRO_5007654542Add
BLAST

Proteomic databases

PaxDbiE9KL26.
PRIDEiE9KL26.

Expressioni

Gene expression databases

BgeeiE9KL26.
GenevisibleiE9KL26. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000278407.

Structurei

3D structure databases

ProteinModelPortaliE9KL26.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini151 – 498348SERPINInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
KOiK04001.

Family and domain databases

InterProiIPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SMARTiSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9KL26-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASRLTLLTL LLLLLAGDRA SSNPNATSSS SQDPESLQDR GEGKVATTVI
60 70 80 90 100
SKMLFVEPIL EVSSLPTTNS TTNSATKITA NTTDEPTTQP TTEPTTQPTI
110 120 130 140 150
QPTQPTTQLP TDSPTQPTTG SFCPGPVTLC SDLESHSTEA VLGDALVDFS
160 170 180 190 200
LKLYHAFSAM KKVETNMAFS PFSIASLLTQ VLLGAGENTK TNLESILSYP
210 220 230 240 250
KDFTCVHQAL KGFTTKGVTS VSQIFHSPDL AIRDTFVNAS RTLYSSSPRV
260 270 280 290 300
LSNNSDANLE LINTWVAKNT NNKISRLLDS LPSDTRLVLL NAIYLSAKWK
310 320 330 340 350
TTFDPKKTRM EPFHFKNSVI KVPMMNSKKY PVAHFIDQTL KAKVGQLQLS
360 370 380 390 400
HNLSLVILVP QNLKHRLEDM EQALSPSVFK AIMEKLEMSK FQPTLLTLPR
410 420 430 440 450
IKVTTSQDML SIMEKLEFFD FSYDLNLCGL TEDPDLQVSA MQHQTVLELT
460 470 480 490 500
ETGVEAAAAS AISVARTLLV FEVQQPFLFV LWDQQHKFPV FMGRVYDPRA
Length:500
Mass (Da):55,154
Last modified:April 5, 2011 - v1
Checksum:i8B5E874833EA6C05
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei500 – 5001Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU727623 mRNA. Translation: ADU87625.1.
KU177948 mRNA. Translation: ALQ33406.1.
RefSeqiNP_000053.2. NM_000062.2.
NP_001027466.1. NM_001032295.1.
UniGeneiHs.384598.

Genome annotation databases

GeneIDi710.
KEGGihsa:710.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU727623 mRNA. Translation: ADU87625.1.
KU177948 mRNA. Translation: ALQ33406.1.
RefSeqiNP_000053.2. NM_000062.2.
NP_001027466.1. NM_001032295.1.
UniGeneiHs.384598.

3D structure databases

ProteinModelPortaliE9KL26.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000278407.

Protein family/group databases

MEROPSiI04.024.

Proteomic databases

PaxDbiE9KL26.
PRIDEiE9KL26.

Protocols and materials databases

DNASUi710.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi710.
KEGGihsa:710.

Organism-specific databases

CTDi710.

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
KOiK04001.

Miscellaneous databases

GenomeRNAii710.

Gene expression databases

BgeeiE9KL26.
GenevisibleiE9KL26. HS.

Family and domain databases

InterProiIPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SMARTiSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiPS00284. SERPIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins."
    Li J., Liu F., Wang H., Liu X., Liu J., Li N., Wan F., Wang W., Zhang C., Jin S., Liu J., Zhu P., Liu Y.
    Mol. Cell. Proteomics 9:2517-2528(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Li J.Y.
    Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiE9KL26_HUMAN
AccessioniPrimary (citable) accession number: E9KL26
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 6, 2016
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.