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Protein

Endochitinase 1

Gene

chit1

Organism
Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium anisopliae (strain ARSEF 23))
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods). Participates in the infection process and directly acts in the penetration process of the host cuticle (By similarity).By similarity

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei172Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Chitin degradation, Polysaccharide degradation, Virulence
LigandChitin-binding

Protein family/group databases

CAZyiGH18. Glycoside Hydrolase Family 18.

Names & Taxonomyi

Protein namesi
Recommended name:
Endochitinase 1 (EC:3.2.1.14)
Alternative name(s):
Chitinase 1
Gene namesi
Name:chit1
ORF Names:MAA_02685
OrganismiMetarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium anisopliae (strain ARSEF 23))
Taxonomic identifieri655844 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesClavicipitaceaeMetarhizium
Proteomesi
  • UP000002498 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000042986523 – 424Endochitinase 1Add BLAST402

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi74N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi78N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi96N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi248N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi347N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

SMRiE9ERT9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

KOiK01183.
OrthoDBiEOG092C2AAM.

Family and domain databases

InterProiView protein in InterPro
IPR011583. Chitinase_II.
IPR029070. Chitinase_insertion.
IPR001223. Glyco_hydro18_cat.
IPR001579. Glyco_hydro_18_chit_AS.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF00704. Glyco_hydro_18. 1 hit.
SMARTiView protein in SMART
SM00636. Glyco_18. 1 hit.
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF54556. SSF54556. 1 hit.
PROSITEiView protein in PROSITE
PS01095. CHITINASE_18. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E9ERT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSLFAQSLA IIATLQATLG LATPVSAPDT VTGKHAGGYV NAVYFTNWGI
60 70 80 90 100
YGRNYQPADL PASQISHVLY SFLNLSNNGT VYSGDSWADI DKHYPNDSWN
110 120 130 140 150
DVGNNVYGCV KQLYLLKKAN RNMKTMLSIG GWTWSTNFPA AASTAATRSN
160 170 180 190 200
FAKSAVTIMK DWGFDGIDVD WEYPADDAQA ANMVLLLQAV RDELDAYAAK
210 220 230 240 250
FAQGYHFQLS IAAPAGPANY NKLHLGDLGK VLDYINLMAY DFSGSWSNSS
260 270 280 290 300
AHNANLYANP GNLNATPFNT DDAVNDYIKG GVPASKIVLG MPIYGKSFQK
310 320 330 340 350
TNGIGKPFSG VGDGSWENGI WDYKVLPKAG ATVIYDDVAK GYYSYDNRTQ
360 370 380 390 400
ELISYDTPDI TKEKVTYLKS KGLGGSMFWE ASADRQGPDS LIGTSSNKLG
410 420
GPDTTENLLN YPDSKYDNMR KQMA
Length:424
Mass (Da):46,113
Last modified:April 5, 2011 - v1
Checksum:i9E460A593B3EE324
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADNJ02000004 Genomic DNA. Translation: EFZ01456.1.
RefSeqiXP_007818874.1. XM_007820683.1.

Genome annotation databases

EnsemblFungiiEFZ01456; EFZ01456; MAA_02685.
GeneIDi19256971.
KEGGimaj:MAA_02685.

Similar proteinsi

Entry informationi

Entry nameiCHI1_METRA
AccessioniPrimary (citable) accession number: E9ERT9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 9, 2014
Last sequence update: April 5, 2011
Last modified: May 10, 2017
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families