Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Endochitinase 3

Gene

chi3

Organism
Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium anisopliae (strain ARSEF 23))
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods). Participates in the infection process and directly acts in the penetration process of the host cuticle. Involved in heat-shock adaptation (By similarity).By similarity

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei170Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Chitin degradation, Polysaccharide degradation, Virulence
LigandChitin-binding

Protein family/group databases

CAZyiGH18. Glycoside Hydrolase Family 18.

Names & Taxonomyi

Protein namesi
Recommended name:
Endochitinase 3 (EC:3.2.1.14)
Alternative name(s):
Chitinase 3
Gene namesi
Name:chi3
ORF Names:MAA_01212
OrganismiMetarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium anisopliae (strain ARSEF 23))
Taxonomic identifieri655844 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesClavicipitaceaeMetarhizium
Proteomesi
  • UP000002498 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000042986920 – 317Endochitinase 3Add BLAST298

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi25N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi49N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi169N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi245N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

SMRiE9ENC6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

KOiK01183.
OrthoDBiEOG092C49QH.

Family and domain databases

InterProiView protein in InterPro
IPR001223. Glyco_hydro18_cat.
IPR001579. Glyco_hydro_18_chit_AS.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF00704. Glyco_hydro_18. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiView protein in PROSITE
PS01095. CHITINASE_18. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E9ENC6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFVRNALVVT GLLAALTQAA PAERNTSRHK LTVYWGAEDD TTTLDDVCND
60 70 80 90 100
SSYDVVNLAF LSHFFSGGGY PRMSIGNLDG PSRAQKKAGA TGLQDGSSLV
110 120 130 140 150
KSIKNCQSKG KPVILSMGGA TDYSDVQLHS DAQGQQIANT VWDLFLGGTD
160 170 180 190 200
HKELRPFGDV KLDGVDLDNE TNDGTGYLAM AKQFKANFQK DTSKKYYITA
210 220 230 240 250
APQCPYPDQS EPLDVCRLLD WVQVQFYNNG NCNIAQSGFA TAVKNWSRGI
260 270 280 290 300
GSGVQLYIGA LASGADGDEG YVDAAVLNRA IDQVKAMDLP NFGGAMLWEA
310
QLAVNNGNYQ KEIKANL
Length:317
Mass (Da):34,157
Last modified:April 5, 2011 - v1
Checksum:i58EAE71E549E9399
GO

Sequence cautioni

The sequence EFZ04138 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADNJ02000008 Genomic DNA. Translation: EFZ04138.2. Different initiation.
RefSeqiXP_007817401.2. XM_007819210.2.

Genome annotation databases

EnsemblFungiiEFZ04138; EFZ04138; MAA_01212.
GeneIDi19255498.
KEGGimaj:MAA_01212.

Similar proteinsi

Entry informationi

Entry nameiCHI3_METRA
AccessioniPrimary (citable) accession number: E9ENC6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 9, 2014
Last sequence update: April 5, 2011
Last modified: May 10, 2017
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families