SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E9ED72

- DAPB_METAQ

UniProt

E9ED72 - DAPB_METAQ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable dipeptidyl-aminopeptidase B

Gene
DAPB, MAC_07820
Organism
Metarhizium acridum (strain CQMa 102)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline By similarity.

Catalytic activityi

Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei759 – 7591Charge relay system By similarity
Active sitei836 – 8361Charge relay system By similarity
Active sitei869 – 8691Charge relay system By similarity

GO - Molecular functioni

  1. aminopeptidase activity Source: UniProtKB-KW
  2. serine-type peptidase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Aminopeptidase, Hydrolase, Protease, Serine protease

Names & Taxonomyi

Protein namesi
Recommended name:
Probable dipeptidyl-aminopeptidase B (EC:3.4.14.5)
Short name:
DPAP B
Gene namesi
Name:DAPB
ORF Names:MAC_07820
OrganismiMetarhizium acridum (strain CQMa 102)
Taxonomic identifieri655827 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesClavicipitaceaemitosporic ClavicipitaceaeMetarhizium
ProteomesiUP000002499: Unassembled WGS sequence

Subcellular locationi

Vacuole membrane; Single-pass type II membrane protein By similarity
Note: Lysosome-like vacuoles By similarity.

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 9393Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei94 – 11421Helical; Signal-anchor for type II membrane protein; Reviewed predictionAdd
BLAST
Topological domaini115 – 934820Vacuolar Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. vacuolar membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 934934Probable dipeptidyl-aminopeptidase BPRO_0000412148Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi354 – 3541N-linked (GlcNAc...) Reviewed prediction
Glycosylationi576 – 5761N-linked (GlcNAc...) Reviewed prediction
Glycosylationi818 – 8181N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S9B family.

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiEOG72VHFG.

Family and domain databases

Gene3Di2.140.10.30. 1 hit.
3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view]
PfamiPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

E9ED72-1 [UniParc]FASTAAdd to Basket

« Hide

MAPPFTDDPE SQRPSTSRLS QDSLSSVSTT SLVFDRIQEE MDRDPSSSRS    50
ARRDLLSATK DEGDYEDASE TGAFLGQPGV PLQRQPMDRG FRRILIIIGA 100
VFVGAWLAGL GVFVLSGSYR HESDSEHDPD AISRGSGKAV TMDQVFGGFW 150
SAKSRSISWI ADPDGGDGLL LEVGTANGYL VVEDVRADKQ GTDTTSRQTA 200
DTQPAKPRVL MKDPYFMYNG EIKRPEWNEP SPDLKKVLLA VNLEKNWRHS 250
FQATYFILHV ETAQIQPLVP DNVNAKVQLA NWSPKSDAIS FTMDNNIYIR 300
RLNQANDVVQ ITKDGGPEYF YGIPDWVYEE EVLAGRSATW WSDDGNYLAF 350
LRTNETAVPE YAIEYYIQRP SGKKPAVGEE AYPEIRKIKY PKPGAHNPVV 400
DVQYYDVSKG DVFSISAPDE FPDKDRIISN VLWAGNKVLL KQSNRVGDFL 450
KVILVDPSER KAKIVNSINI AEIDGGWFEI SHTMTYIPAD PSKGRQQDGY 500
VDTVIHEGYE HIGYFTPIDN PKPIMLTSGS WEVEDAPSAV DLDNNLVYFV 550
ATKESSIQRH VYSVKLDGSN LTPLTNTSSE GYYAVSFSSR SGFALLSYQG 600
PKIPYQKVIS TPSIPIEFSR TIEDNAGLAD KAKKHELPIL KYGTLQLPNG 650
ISVNYLERRP PHFNPKKKYP ILFQQYSGPK SQTVTKKFAV NFQSYVASSL 700
GYLVVTIDPR GTGFLGRQHR VVVRSQLGVL EAQDHIAAAK HYSSLPYVDP 750
SRLAIWGWSY GGFQTLKTLE VDAGDTFSYG MAVAPVTDWR FYDSIYTERY 800
MRLPQDNAAG YDASAVHNAT ALGMSKRFLI MHGSADDNVH FQNSLKLLDY 850
LDLARIENYD VHVFPDSDHG IAFHGANRMV YDSKSEFSVL FSWILSPMLT 900
LSGLNNWLVN AFNGEWLKIA DPKPIDTKKR RHVS 934
Length:934
Mass (Da):104,515
Last modified:April 5, 2011 - v1
Checksum:i89ED7648E4BC6754
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GL698555 Genomic DNA. Translation: EFY86155.1.
RefSeqiXP_007814160.1. XM_007815969.1.

Genome annotation databases

GeneIDi19252131.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GL698555 Genomic DNA. Translation: EFY86155.1 .
RefSeqi XP_007814160.1. XM_007815969.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 19252131.

Phylogenomic databases

OrthoDBi EOG72VHFG.

Family and domain databases

Gene3Di 2.140.10.30. 1 hit.
3.40.50.1820. 1 hit.
InterProi IPR029058. AB_hydrolase.
IPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view ]
Pfami PF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view ]
SUPFAMi SSF53474. SSF53474. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequencing and comparative transcriptomics of the model entomopathogenic fungi Metarhizium anisopliae and M. acridum."
    Gao Q., Jin K., Ying S.-H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X., Xie X.-Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S., Zhong Y., Ma L.-J.
    , St Leger R.J., Zhao G.-P., Pei Y., Feng M.-G., Xia Y., Wang C.
    PLoS Genet. 7:E1001264-E1001264(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CQMa 102.

Entry informationi

Entry nameiDAPB_METAQ
AccessioniPrimary (citable) accession number: E9ED72
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: April 5, 2011
Last modified: July 9, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi