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E9CV02 (DPEP2_COCPS) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative dipeptidase CPSG_01350

EC=3.4.13.19
Gene names
ORF Names:CPSG_01350
OrganismCoccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus) [Complete proteome]
Taxonomic identifier443226 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesCoccidioides

Protein attributes

Sequence length461 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolyzes a wide range of dipeptides By similarity.

Catalytic activity

Hydrolysis of dipeptides.

Cofactor

Zinc By similarity.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the peptidase M19 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 461461Putative dipeptidase CPSG_01350
PRO_0000411217

Regions

Transmembrane35 – 5218Helical; Potential

Sites

Metal binding901Zinc 1; catalytic By similarity
Metal binding921Zinc 1; catalytic By similarity
Metal binding2031Zinc 1; catalytic By similarity
Metal binding2031Zinc 2; catalytic By similarity
Metal binding2741Zinc 2; catalytic By similarity
Metal binding2951Zinc 2; catalytic By similarity
Binding site2301Substrate By similarity
Binding site3061Substrate By similarity
Binding site3661Substrate By similarity

Amino acid modifications

Glycosylation3791N-linked (GlcNAc...) Potential
Disulfide bond142 ↔ 232 By similarity

Sequences

Sequence LengthMass (Da)Tools
E9CV02 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 1BE71D05BCD42F28

FASTA46151,063
        10         20         30         40         50         60 
MSARDNEKGS ARSQPSHAAA SEIENVPRPS RQQSWTGTMI KVFIICACAG IVSKYIIPLD 

        70         80         90        100        110        120 
SIFKSVHIDP HDYATRANRI LSTTPLIDGH NDLPYLIRLE TKNKIYDHEK LPFRTGLLSH 

       130        140        150        160        170        180 
TDQIKIQEGK LGGQFWSVFV ECATDPNAEI DDPTWAVRDT LEQIDVTKRL VQEYPDLLEY 

       190        200        210        220        230        240 
CESASCAKAA FKRGKVGSFL GIEGGHQIGN SLASLRQVYD LGVRYITVTH NCDNAFATAA 

       250        260        270        280        290        300 
STVAVGKPDL GLTDFGREFV KEMNRLGMLV DLSHVSHQTM RDILSVTKAP VMFSHSSSYA 

       310        320        330        340        350        360 
LSKHLRNVPD DVLNGVTKNG GVVMVTFVPS FLKVDDPASA TIHDAVDHIL HVAKVAGWDH 

       370        380        390        400        410        420 
VGIGSDFDGT ADVPEGLENV SKYPRLIELL LERGVTDEQA RKLIGENILR VWSNVEEIAE 

       430        440        450        460 
NIRALGEKPN EETWSGRKWT AAIDIPMPFM FKDSADKRKE L 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GL636487 Genomic DNA. Translation: EFW21193.1.

3D structure databases

ProteinModelPortalE9CV02.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

OrthoDBEOG7XM371.

Family and domain databases

InterProIPR000180. Renal_dipep_AS.
IPR008257. Renal_dipep_fam.
[Graphical view]
PANTHERPTHR10443. PTHR10443. 1 hit.
PfamPF01244. Peptidase_M19. 1 hit.
[Graphical view]
PROSITEPS00869. RENAL_DIPEPTIDASE_1. 1 hit.
PS51365. RENAL_DIPEPTIDASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDPEP2_COCPS
AccessionPrimary (citable) accession number: E9CV02
Entry history
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: April 5, 2011
Last modified: June 11, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries