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E9BF59 (E9BF59_LEIDB) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histone deacetylase PIRNR PIRNR037913
EC=3.5.1.98 PIRNR PIRNR037913
Gene names
ORF Names:LDBPK_210740 EMBL CBZ33885.1
OrganismLeishmania donovani (strain BPK282A1) [Complete proteome]
Taxonomic identifier981087 [NCBI]
Taxonomic lineageEukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmaniinae › Leishmania ›

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone. PIRNR PIRNR037913

Subcellular location

Nucleus By similarity PIRNR PIRNR037913.

Sequence similarities

Belongs to the histone deacetylase family. HD Type 1 subfamily. PIRNR PIRNR037913

Sequences

Sequence LengthMass (Da)Tools
E9BF59 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 0E5EA4D37A4C8459

FASTA43047,389
        10         20         30         40         50         60 
MHAVHKDDAR APLLNTESRC RVALIDTSGY ASDMNISAFV PQHAMKPYRV LAAMEIVRSL 

        70         80         90        100        110        120 
KIDAHCRTVV PPLVKVEELM AYHTDTYLAN LGLHSCRSWL WNAETSKVFF SGDCPPVEGL 

       130        140        150        160        170        180 
MEHSIATASG TLMGAVLLNS GQVDVAVHWG GGMHHSKCGE CSGFCYVNDI VLGILELLKC 

       190        200        210        220        230        240 
HDRVLYVDID MHHGDGVDEA FCTSDRVFTL SLHKFGESFF PGTGHPRDVG YGRGRYYSMN 

       250        260        270        280        290        300 
LAVWDGITDF YYLGVFEHAL HSIVRRYSPD VIVLQCGADS LAGDRLGLLN LSSFGHGQCV 

       310        320        330        340        350        360 
QAVRDLGIPM LALGGGGYTI RNVAKLWAYE TSILTGHPLP PNTVLPVAEM PLSGWLFQDS 

       370        380        390        400        410        420 
PLLIVAQDRS NHVLPGLHCQ RAYQMMTEQI DRHVPHIQPH PRLQKASTEA AAVDKQVEDG 

       430 
TTAVEDFKRQ

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References

[1]"Whole genome sequencing of Leishmania donovani clinical lines reveals dynamic variation related to drug resistance."
Downing T., Imamura H., Sanders M., Decuypere S., Hertz-Fowler C., Clark T.G., Rijal S., Sundar S., Quail M.A., De Doncker S., Maes I., Vanaerschot M., Stark O., Schonian G., Dujardin J.C., Berriman M.
Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BPK282A1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FR799608 Genomic DNA. Translation: CBZ33885.1.
RefSeqXP_003860591.1. XM_003860543.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID13386404.
KEGGldo:LDBPK_210740.

Phylogenomic databases

HOGENOMHOG000225180.
KOK06067.

Family and domain databases

Gene3D3.40.800.20. 1 hit.
InterProIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERPTHR10625. PTHR10625. 1 hit.
PfamPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSPR01270. HDASUPER.
PR01271. HISDACETLASE.
ProtoNetSearch...

Entry information

Entry nameE9BF59_LEIDB
AccessionPrimary (citable) accession number: E9BF59
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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