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Protein

Hexokinase

Gene

LMXM_21_0240

Organism
Leishmania mexicana (strain MHOM/GT/2001/U1103)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:LMXM_21_0240Imported
OrganismiLeishmania mexicana (strain MHOM/GT/2001/U1103)Imported
Taxonomic identifieri929439 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
ProteomesiUP000007259 Componenti: Chromosome 21

Interactioni

Protein-protein interaction databases

STRINGi929439.XP_003875264.1.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000162670.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9AUZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGENRREKTI SSSPSTRPPP SGLPHVSLSP SLTVSPLTPP APHIHARAST
60 70 80 90 100
SNPHVLATPQ PPSTLHRATP ILSSPTHTPP SPSPLPSTPS QWPPANLLSH
110 120 130 140 150
IAIRDSDSEE MRYIKQRLAL ASLATQFTMS PEKMKQLTMY MIHEMVEGLE
160 170 180 190 200
GRPSTVRMLP SFVYTSDPAK ATGVYYALDL GGTNFRVLRV SLRGGKVDDR
210 220 230 240 250
TDSKFVIPKS ALVGDATDLF DFIAQSVKKM MSENAPEDLE KRVPLGFTFS
260 270 280 290 300
FPVDQKAVNK GLLIKWTKGF STKNVEGSDV VELLQASLRR VRVNVNVVAL
310 320 330 340 350
CNDTVGTLVA RYFVDTDVQV GVIIGTGSNA CYFERASAVT KDPAVSARGN
360 370 380 390 400
AVTPINMECG NFDSKYKYAL PITVYDDEMD AITPNRENQR QEKLVSGMYL
410 420 430 440 450
GEISRRLIVH LAHLGCLPRG LVDGLCKPWA FESKHMGMVA ADQMPGLQFT
460 470 480 490 500
RELIKRVAGV DVTDTSDLHT IREACCLVRN RAAQQGSVFT AAPMLKTRTQ
510 520 530 540 550
GLATVAVDGS VYEKTPSFQR LYQECITSIL GSTSNAKVVL QRDGSGVGAA
560
MICALAVNKK
Length:560
Mass (Da):60,911
Last modified:April 5, 2011 - v1
Checksum:i30B8437C30975430
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR799574 Genomic DNA. Translation: CBZ26772.1.
RefSeqiXP_003875264.1. XM_003875215.1.

Genome annotation databases

GeneIDi13454092.
KEGGilmi:LMXM_21_0240.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR799574 Genomic DNA. Translation: CBZ26772.1.
RefSeqiXP_003875264.1. XM_003875215.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi929439.XP_003875264.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi13454092.
KEGGilmi:LMXM_21_0240.

Phylogenomic databases

HOGENOMiHOG000162670.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MHOM/GT/2001/U1103Imported.

Entry informationi

Entry nameiE9AUZ1_LEIMU
AccessioniPrimary (citable) accession number: E9AUZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 22, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.