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Protein
Submitted name:

Alanine aminotransferase

Gene

ALAT

Organism
Leishmania infantum
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. pyridoxal phosphate binding Source: InterPro
  2. transaminase activity Source: UniProtKB-KW

GO - Biological processi

  1. biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Alanine aminotransferaseImported
Gene namesi
Name:ALATImported
ORF Names:LINJ.12.0580Imported
OrganismiLeishmania infantumImported
Taxonomic identifieri5671 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
ProteomesiUP000008153: Chromosome 12

Structurei

3D structure databases

ProteinModelPortaliE9AGF0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

InParanoidiE9AGF0.
KOiK00814.
OMAiGFECPPE.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

E9AGF0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLRHAARSLS PKQCYISPRV IEAEYAVRGL IPARADEIKA DLATGRGSYA
60 70 80 90 100
FESLVYCNIG NPQSVGQMPL TFYRQVMALV DAPSLLEDAV IAARLPEDAV
110 120 130 140 150
ARARRYLAEI GTGTGAYTES FGYRFARAAV AEHINKLDHG VSPAATVNDI
160 170 180 190 200
CLTDGASMGA KLFLQLLVGG ASDAVMIPVP QYPLYSAQIA LLGGVKVPYF
210 220 230 240 250
LHESEGWAMK LPDLVAAYER CVTESGATPR LFVCINPGNP TGNVLERCVM
260 270 280 290 300
EDVVRFCHER GMLLLADEVY QENVYDTRRR FLSFREVVLG MPEPYCSETM
310 320 330 340 350
LVSLHSTSKG VIGECGRRGG YFCMTNLPAA LRQQVVKLCS INLCANVNGQ
360 370 380 390 400
LMTALMCSPP REGETSYAMH QRECDAIFTG MKERAELLAR ELGNVRGLSC
410 420 430 440 450
QPVEGAMYAF PRIVLPERYA QRNEELNAKE GRRLALDARW ALELLESSGI
460 470 480 490
VVVPGSGFGQ EPGTLHFRIT ILPPLEQIDR MVRAIREFQD RIYEQYA
Length:497
Mass (Da):54,878
Last modified:April 5, 2011 - v1
Checksum:iEF0C50FE4BBBBB57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR796444 Genomic DNA. Translation: CBZ08450.1.
RefSeqiXP_003392302.1. XM_003392254.1.

Genome annotation databases

GeneIDi10966172.
KEGGilif:LINJ.12.0580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR796444 Genomic DNA. Translation: CBZ08450.1.
RefSeqiXP_003392302.1. XM_003392254.1.

3D structure databases

ProteinModelPortaliE9AGF0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10966172.
KEGGilif:LINJ.12.0580.

Phylogenomic databases

InParanoidiE9AGF0.
KOiK00814.
OMAiGFECPPE.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JPCM5Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JPCM5Imported.
  3. "Chromosome and gene copy number variation allow genomic structural differences between species and strains of Leishmania."
    Hilley J.D., Rogers M., Wilkes J., Dickens N.J., Bates P., Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D., Saad W., Seeger K., Berriman M., Smith D.F., Hertz-Fowler C., Mottram J.C.
    Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: JPCM5.

Entry informationi

Entry nameiE9AGF0_LEIIN
AccessioniPrimary (citable) accession number: E9AGF0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: January 7, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.