SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E8YVP3

- E8YVP3_9BURK

UniProt

E8YVP3 - E8YVP3_9BURK

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Isocitrate dehydrogenase, NADP-dependent
Gene
BC1001_4557
Organism
Burkholderia sp. CCGE1001
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei146 – 1461Substrate By similarityUniRule annotation
Sitei256 – 2561Critical for catalysis By similarityUniRule annotation
Metal bindingi351 – 3511Magnesium or manganese By similarity
Sitei421 – 4211Critical for catalysis By similarityUniRule annotation
Binding sitei548 – 5481Substrate By similarityUniRule annotation
Metal bindingi549 – 5491Magnesium or manganese By similarity
Metal bindingi553 – 5531Magnesium or manganese By similarity

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciBSP640510:GI28-4626-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
ORF Names:BC1001_4557Imported
OrganismiBurkholderia sp. CCGE1001Imported
Taxonomic identifieri640510 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000007095: Chromosome 2

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni133 – 1408Substrate binding By similarityUniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

E8YVP3-1 [UniParc]FASTAAdd to Basket

« Hide

MSTPPKIIYT LTDEAPALAT YSLLPIVKAF TRSSGVNVET RDISLAGRII    50
AAFPDYLSPE QKGSDDLAEL GGLTTRPEAN IIKLPNISAS VPQLKAAITE 100
LRDQGYKLPP YPDVATTDTE KDVKARYDKI KGSAVNPVLR EGNSDRRAPL 150
SVKNYARKHP HKMGAWTADS KSHVAHMSGG DFYGSEKSAL IAAAGAVKIE 200
LTAADGTKTV LKEKTPVQAG EVIDASVLSK NALRSFIEKE ISDAKANGVL 250
FSVHLKATMM KVSDPIIFGH VVSVFYKDVL TKHADALAQA GFNPNNGIGD 300
LYARLKDLPA ETAAQIEADI KAQYEQRPQL AMVNSDKGIT SLHVPSDVIV 350
DASMPAMIRE SGKMWGADGA LHDAKAVIPD RCYAGVYQAV IEDCKKNGAF 400
DPVTMGTVPN VGLMAQAAEE YGSHDKTFQI PANGVVRVTD ASGAVLIEQP 450
VEAGDIWRMC QTKDAPVQDW VKLAVNRARA TNTPAVFWLD AARAHDAQII 500
KKVEQYLKDH DTNGLDIRIM TPVEATKFSL ERIRAGKDTI SVTGNVLRDY 550
LTDLFPIMEL GTSAKMLSIV PLMAGGGMFE TGAGGSAPKH VQQLVEEGFL 600
RWDSLGEFLA LAASLEHLSS AYHNPKAQVL AKTLDQATGK FLDNDKSPAR 650
KVGGLDNRGS HFYLAMYWAE ALAEQTEDAA LQAQFAGVAK AMAANEAKIL 700
EELRAAQGKP VDIGGYYRPN VELTSKAMRP SATLNQIVDS IA 742
Length:742
Mass (Da):79,907
Last modified:April 5, 2011 - v1
Checksum:iA171ADEEF9833659
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002520 Genomic DNA. Translation: ADX57946.1.
RefSeqiWP_013591051.1. NC_015137.1.
YP_004231006.1. NC_015137.1.

Genome annotation databases

EnsemblBacteriaiADX57946; ADX57946; BC1001_4557.
GeneIDi10226149.
KEGGibug:BC1001_4557.
PATRICi46902192. VBIBurSp1058_4767.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002520 Genomic DNA. Translation: ADX57946.1 .
RefSeqi WP_013591051.1. NC_015137.1.
YP_004231006.1. NC_015137.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADX57946 ; ADX57946 ; BC1001_4557 .
GeneIDi 10226149.
KEGGi bug:BC1001_4557.
PATRICi 46902192. VBIBurSp1058_4767.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci BSP640510:GI28-4626-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CCGE1001Imported.

Entry informationi

Entry nameiE8YVP3_9BURK
AccessioniPrimary (citable) accession number: E8YVP3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 3, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi