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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia sp. CCGE1001
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei265 – 2651UniRule annotation
Active sitei707 – 7071UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBSP640510:GI28-827-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:BC1001_0820Imported
OrganismiBurkholderia sp. CCGE1001Imported
Taxonomic identifieri640510 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000007095 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi640510.BC1001_0820.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8YG73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSGSARSA RRNTASPNAS IDDAAASPAA ASSTVETTQP PKAKRATSGE
60 70 80 90 100
KAANAAKAVK AEKTSAPVKA DKTVKTSKAD KSGEAAPSAK KGKAKAAGKA
110 120 130 140 150
PVLQAVSEDT VMAAPKTNGR TRDDKDHPLF QDIRYLGRLL GDVLREQEGD
160 170 180 190 200
AVFDVVETIR QTAVRFRRED DNAAAQTLDK KLRSLSPEQT VSVVRAFSYF
210 220 230 240 250
SHLANIAEDR HRNRRHRIHA LAGSAAQPGS IAYALERLVE AGAAATPVLQ
260 270 280 290 300
QFFNDALIVP VLTAHPTEVQ RKSILDAEHD VARLLAERDQ QLTDRERAQN
310 320 330 340 350
ERMLRARVTS LWQTRMLRDS RLTVADEIEN ALSYYRATFL EEIPALYADI
360 370 380 390 400
EEALKEHGLE ARLPPFFQMG SWIGGDRDGN PNVTAETLEH AIARQAEVIF
410 420 430 440 450
EHYLEQVHKL GAELSVSNLL AGASDELKAL AEISPDRSPH RTDEPYRRAL
460 470 480 490 500
IGMYTRLAAS ARVRLGEGAV PLRSAGRGAA PIRATPYDDA SEFVRDLHVL
510 520 530 540 550
MDSLAAHHGA PLAAPRLAPL ARAAEVFGFH LASIDLRQSS DIHEAVIAEL
560 570 580 590 600
LKRAGVHDDY AALDESAKLE VLLAELAQPR PLRLPYAEYS DLVKSELGVL
610 620 630 640 650
EQARVTREKF GARAVRNYII SHTETVSDLV EVMLLQKETG LLQGRLGNAD
660 670 680 690 700
NPAKAALMVI PLFETIPDLR NAPHIMRDLL ALPGADSIIE HQGNEQEVML
710 720 730 740 750
GYSDSNKDGG FLTSNWELYR AELALVSLFN ERGITLRLFH GRGGTVGRGG
760 770 780 790 800
GPTYQAILSQ PPGTVDGQIR LTEQGEVIAS KFGNPEIGRR NLETVVAATL
810 820 830 840 850
EASLLPHGNA PADLPAFEET MQQLSDAAMA SYRALVYETP GFKEYFFEST
860 870 880 890 900
PISEIAELNI GSRPASRKLQ DPKHRKIEDL RAIPWGFSWG QCRLLLTGWY
910 920 930 940 950
GFGSAVAAYL DSAPSDAERG RRLSLLKKMH KSWPFFSTLL SNMDMVLAKT
960 970 980 990 1000
DLAVASRYAA LVSDKKLRKH VFERIVAEWE RTSKVLSEIT GKRERLAENP
1010 1020 1030 1040 1050
LLARSIKNRF PYLDPLNHLQ VELLKRHRAG DTNARVRRGI HLTINGIAAG

LRNTG
Length:1,055
Mass (Da):115,782
Last modified:April 5, 2011 - v1
Checksum:i1594CE4F7A669C83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002519 Genomic DNA. Translation: ADX54274.1.
RefSeqiWP_013587529.1. NC_015136.1.

Genome annotation databases

EnsemblBacteriaiADX54274; ADX54274; BC1001_0820.
KEGGibug:BC1001_0820.
PATRICi46894142. VBIBurSp1058_0845.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002519 Genomic DNA. Translation: ADX54274.1.
RefSeqiWP_013587529.1. NC_015136.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi640510.BC1001_0820.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADX54274; ADX54274; BC1001_0820.
KEGGibug:BC1001_0820.
PATRICi46894142. VBIBurSp1058_0845.

Phylogenomic databases

KOiK01595.

Enzyme and pathway databases

BioCyciBSP640510:GI28-827-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CCGE1001Imported.

Entry informationi

Entry nameiE8YG73_9BURK
AccessioniPrimary (citable) accession number: E8YG73
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 22, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.